SalehLab
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salehlabparis.bsky.social
SalehLab
@salehlabparis.bsky.social
Immunity, insects, viruses, idealism and everything else.
Institut Pasteur
Paris
So happy to be part of #ImmunoCambodia 2025! Magnificent setting, great Science. Master classes in the morning, art of grant writing in afternoon. Such a range of nationalities between students and instructors. What energy! Everyone is here to learn and to be inspired. #ImmunoEducation #IUISCourse
November 25, 2025 at 3:28 PM
This #WorldMosquitoDay, @salehlabparis.bsky.social is proud to be part of the fight against mosquitoes and the viruses they transmit. 🦟🔬 #ResearchForHealth #ScienceInAction
Photo credit: our own Annabelle Henrion-Lacritick 👩‍🔬
August 20, 2025 at 11:04 AM
Smiling as I attend the @amersocvirology.bsky.social meeting in Montreal - my first as Chair of Virology at @pasteur.fr. The hall is packed with 1,600+ brilliant minds. Great to reconnect with colleagues and to see first hand so much emerging talent.
#LoveVirology
July 16, 2025 at 8:55 PM
Thrilled to receive @anrs-mie.bsky.social grant with @lambrechtslab.bsky.social & @retrogenomics.bsky.social! Making mosquitoes intolerant to arboviruses. Thanks @pasteur.fr, @inserm.fr & @cnrs.fr for support. Exciting times for #ARBORETRO project! Stay tunned.
April 10, 2025 at 3:09 PM
For #IWD2025, the men from @salehlabparis.bsky.social share #ForAllWomenAndGirls:
We celebrate women’s strength, resilience, and achievements. Let’s honor those who fight every day, and stand united against discrimination and violence—equality is a right, and together we can build a fairer world.
March 8, 2025 at 1:07 PM
Kicking off the new year in style! Activities included: finding the best "galette de rois" -yummy seasonal french pastry- of Paris (Mori Yoshida came in top again!), crowning of royalty, and of course a new beautiful group photo. #FoodieLife #TeamBuilding #ProudPI #LoveScience
January 9, 2025 at 9:33 PM
What a pleasure to have hosted Shaeri Mukherjee for a minisabbatical in our lab! 🌟 Her brilliant science and insights have enriched us in so many ways. We’re already missing her! Thanks to @pasteur.fr and @UCSF for making this possible. 🧬💡#LoveScience #PILife #NewFriends
December 13, 2024 at 2:29 AM
The best part of being a PI? Moments like this: running into Yasu Suzuki (not yet in BS) and @virotick.bsky.social, former Saleh Lab alumni, at #MBSJ2024 in Fukuoka. They're both PIs now, and I was so proud, I nearly burst out of my clothes! 🥹 #FullCircle #LoveScience #WomenInSTEM #LoveVirology
November 29, 2024 at 1:10 AM
Hello! I will be presenting today at #MBSJ2024, in Fukuoka, at the symposium organized by -former Saleh lab member- Professor Yasu Suzuki and Prof Yasuko Orba. I will be discussing the work of @cassandrakoh.bsky.social on mosquito viromes. Come if you are around!
November 28, 2024 at 12:57 AM
Hello Tokyo friends, I will be presenting our work on retrotransposons and antiviral immunity in insects tomorrow at 7 pm at @tokyouniversity.bsky.social. Please stop by to say hi if you are around!
November 19, 2024 at 1:25 PM
Persistent viral infections are extremely common in laboratory fly stocks and our study demonstrates that they have profound physiological impacts. Check out our preprint to see even more! 10/11
November 17, 2023 at 4:05 PM
Even more surprising? Ectopic activation of Sting in mock-infected flies recapitulated the homeostatic disruption seen in infected guts and shortened lifespan just as much as viral infection. 8/11
November 17, 2023 at 4:04 PM
Yes it can! Viral infection did not induce intestinal stem cell proliferation in Relish or Sting mutants and the transcriptomes of mutant flies showed a clear absence of the mitogenic signaling that was seen in wild-type flies. The mutants also had prolonged lifespans! 7/11
November 17, 2023 at 4:03 PM
How does viral infection induce intestinal stem cell proliferation? To find out we turned to RNA-seq 🧬. Drosophila A virus infection induced a strong NF-kB transcriptional response involving Relish and Sting. Could this response to infection modulate cellular turnover? 6/11
November 17, 2023 at 4:03 PM
We wondered if increased cellular turnover is an antiviral mechanism or a tolerance strategy that is required to repair damage caused by viral infection. To our surprise, inhibiting intestinal stem cell proliferation actually prolonged the lifespan of infected flies!  5/11
November 17, 2023 at 4:02 PM
We saw that the organization of the intestinal epithelium was disrupted in Drosophila A virus-infected flies. The guts of these flies also resembled those of aged flies - consistently high levels of intestinal stem cell proliferation and accumulation of Escargot + cells. 4/11
November 17, 2023 at 4:01 PM
Find @salehlabparis.bsky.social members, Mauro and Eugenia, at the International Conference on Nucleic Acid Immunity, in Dresden. Thanks to the organizers for the talk and the poster slot to present our results. #NucleicAcidsRock #LoveImmunity #LoveScience
October 26, 2023 at 7:22 AM