Pabi Sahoo
banner
sahoolab.bsky.social
Pabi Sahoo
@sahoolab.bsky.social
Assistant Professor at Rutgers University | Molecular Neurobiologist | Neural Repair | Neurodevelopment
Very exciting results from the Fanzilber lab!
May 16, 2025 at 3:52 PM
Reposted by Pabi Sahoo
ATP - not only a fuel source! Intriguing work from Marco Terenzio and colleagues at the OIST

www.science.org/doi/full/10....
Loss of intracellular ATP affects axoplasmic viscosity and pathological protein aggregation in mammalian neurons
The protective role of ATP in neurons reduces protein aggregation and neurodegeneration.
www.science.org
April 26, 2025 at 7:22 PM
Pretty cool!
March 7, 2025 at 9:29 PM
Our CNS regeneration work has now been published in @PNAS. It was a huge undertaking in collaboration with @Twiss @Benowitz @WardLab_Emory @KristyWelshhans @Marktuszynski @jenniferDulin
@ArthurEnglish @JohnHolule labs. Thank you all, and @MerkinPnnrCtr, for funding.

www.pnas.org/doi/10.1073/...
Disruption of G3BP1 granules promotes mammalian CNS and PNS axon regeneration | PNAS
Depletion or inhibition of core stress granule proteins, G3BP1 in mammals and TIAR-2 in Caenorhabditis elegans, increases the growth of spontaneous...
www.pnas.org
February 28, 2025 at 2:16 PM
First peer reviewed article from our lab is now out. If you are new to stress granule field, you will find this manuscript helpful. Big shout out to @Meghal Desai @keyagulati @Manasi Agrawal, @Shruti Ghumra Thanks @MerkinPnnrCtr for funding 🙏🏼

journals.lww.com/nrronline/ab...
Stress granules: guardians of cellular health and triggers... : Neural Regeneration Research
play a critical role in minimizing cellular damage during stress. Composed of heterogeneous ribonucleoprotein complexes, stress granules are enriched not only in mRNAs but also in noncoding RNAs and v...
journals.lww.com
February 25, 2025 at 2:32 PM
G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration: Cell Reports www.cell.com/cell-reports...
G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration
Boraas et al. identify that mRNAs and the stress granule RNA-binding protein G3BP1 form ribonucleoprotein (RNP) complexes at FAs. These RNPs regulate FA protein mobility and cell migration under norma...
www.cell.com
February 1, 2025 at 3:15 PM