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We are thrilled to announce Parasite Day with PEERs in Parasitology (PiP), on June 27, 2025, from 9:00 am to 1:00 pm EDT! This virtual symposium will spotlight groundbreaking work in parasitology by scientists from historically excluded backgrounds.
We are thrilled to announce Parasite Day with PEERs in Parasitology (PiP), on June 27, 2025, from 9:00 am to 1:00 pm EDT! This virtual symposium will spotlight groundbreaking work in parasitology by scientists from historically excluded backgrounds.
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PfAnchor is essential for apicoplast fission and inheritance in malaria parasites. Targeting this process could open up new avenues for antimalarial therapies!
Check out the full story and let us know what you think!
#U_ExM #malaria #cellbiology #apicoplast #parasites #preprint
PfAnchor is essential for apicoplast fission and inheritance in malaria parasites. Targeting this process could open up new avenues for antimalarial therapies!
Check out the full story and let us know what you think!
#U_ExM #malaria #cellbiology #apicoplast #parasites #preprint
PfAnchor interacts with PfDyn2, a dynamin-like GTPase. This is the first evidence of an apicoplast-specific dynamin adaptor in malaria parasites—think of it as the missing link in organelle fission!
PfAnchor interacts with PfDyn2, a dynamin-like GTPase. This is the first evidence of an apicoplast-specific dynamin adaptor in malaria parasites—think of it as the missing link in organelle fission!
Treating parasites with azithromycin (which disrupts apicoplast structure) rescues the division defect caused by PfAnchor loss. This shows that PfAnchor’s role is tightly linked to the apicoplast’s unique shape.
Treating parasites with azithromycin (which disrupts apicoplast structure) rescues the division defect caused by PfAnchor loss. This shows that PfAnchor’s role is tightly linked to the apicoplast’s unique shape.
Conditional depletion of PfAnchor doesn’t just mess up apicoplast fission—it causes incomplete cytokinesis and kills the parasite. No PfAnchor, no proper cell division!
Conditional depletion of PfAnchor doesn’t just mess up apicoplast fission—it causes incomplete cytokinesis and kills the parasite. No PfAnchor, no proper cell division!
Using U-ExM, we could literally expand the parasites and see PfAnchor hugging the apicoplast throughout the blood-stage. It’s like zooming in with a biological magnifying glass!
Using U-ExM, we could literally expand the parasites and see PfAnchor hugging the apicoplast throughout the blood-stage. It’s like zooming in with a biological magnifying glass!
PfAnchor (Pf3D7_0613600) was hiding in plain sight—previously uncharacterized but highly conserved in Plasmodium! We found that it localizes to the apicoplast, a plastid essential for parasite survival.
PfAnchor (Pf3D7_0613600) was hiding in plain sight—previously uncharacterized but highly conserved in Plasmodium! We found that it localizes to the apicoplast, a plastid essential for parasite survival.
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