I'm deeply honored to receive the 16th Hypertension Research Award for an outstanding paper from the Japanese Society of Hypertension!!

This award is not mine – it is ours who are involved in the J-MICC Study and all related people through my journey.

🧬 PRSs in practice (2/5): Do higher-risk polygenic risk score (PRS) results really cause distress?

Evidence so far doesn’t suggest substantial or lasting psychological harm — though research remains limited.

👉 rdcu.be/eNeKN

#Genomics #PolygenicRiskScores #Risk #MentalHealth #Depression #Anxiety

Our paper is out from Jour al of Nutrition! Abdominal
obesity defined by *Body roundness index* (BRI) has a U-shaped association with mortality.

www.sciencedirect.com/science/arti...

3 posters from our lab in #ASHG2025 🧬 pls stop by and join us!

1️⃣ Okumiyama H: ABCA1 DNAm -> cognitive function (15th, 8072W)
2️⃣ Tsuboi Y: AHRR DNAm -> cancer (17th, 9024F)
3️⃣ Me: Education PGS -> Lifestyles & Diseases (17th, 9175F)

Look forward to autumn breeze in Boston🇺🇸

Now published! Our paper on:
(1) Accurate sequencing of sperm at scale
(2) Positive selection of spermatogenesis driver mutations across the exome
(3) Offspring disease risks from male reproductive aging
[1/n]
www.nature.com/articles/s41...

Excited to share that I’m launching a Computational Genetics Lab spanning MGB Personalized Medicine, Cardiovascular Research Center at MGH, @harvardmed.bsky.social, and @broadinstitute.org. Our research focuses on the genetics of common diseases, with a particular emphasis on cardiovascular disease.

Interested in integrating our R tools into Galaxy?

👉 apply if you like:

- #rstats SW development
- contributing to @bioconductor.bsky.social and @galaxyproject.bsky.social
- large-scale #metabolomics data analysis
- hiking ⛰️

📍 Bolzano, 🇮🇹
⏲️ 3 year position

🔗 info and apply: bit.ly/46AMawx

🚨 This will become a curated list of awesome tools for complex trait genetics, **add yours**! it may become a review in which case those who contribute are invited as co-authors.

I probably won't have time to make a video out of this.

But the materials are available online, and should be pretty self-explanatory.

Hope this is useful to some people.

privefl.github.io/statgen-cour...