I think NHLBI mostly ignored with instructions about multi-year funding as well (and perhaps others).

So, for R01s, NCI, committed 110% of the funds from FY24 in FY25, yet made 91% as many awards, and 440/589 = 75% as many new awards.

Similar patterns are seen for other mechanism, likely reflecting the effect of multi-year funding.

4/n

In 2024, there were about 17,616 new projects awarded by the NIH. In 2025, this number was 11,190 (my number includes things like supplements). That is an ~37% cut in funding of new projects by the NIH.

Here are the results in terms of the number of projects.

The number of funded projects in FY2025 is 4014 fewer than the number for FY2024.

2/3

NCI:

2022 - 2963 new grants awarded
2023 - 2966 new grants
2024 - 2612
2025 - 1431

😐

NIAID:

2022 - 2258 new grants
2023 - 2182 new grants
2024 - 2217
2025 - 1584

😐

Also, of the 128 new R01, 35 of them have been issued as multi-year. Three two-year, six three year and 26 four year. That is another ~ 41 new R01 that will not be funded this year due to the multi-year funding policy