Rudnicki Lab
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rudnicki-lab.bsky.social
Rudnicki Lab
@rudnicki-lab.bsky.social
Hello everyone! Welcome to the official Bluesky account for the Rudnicki Lab. We study the biology of skeletal muscle stem cells 🔬🧫🧬 | Ottawa, ON, Canada 🇨🇦
John Saber, a PhD candidate from our lab recently and successfully defended his thesis at the University of Ottawa 🎉

Congratulations on this amazing achievement! He did an amazing job in the lab and in his project. 🧫🔬🧬
January 31, 2025 at 3:43 PM
Ending this year the best way ✨️

🚨PUBLICATION ALERT🚨

"Intrinsic muscle stem cell dysfunction contributes to impaired regeneration in the mdx mouse, Marie Esper et al."
onlinelibrary.wiley.com/doi/10.1002/...
Intrinsic Muscle Stem Cell Dysfunction Contributes to Impaired Regeneration in the mdx Mouse
Background Duchenne muscular dystrophy (DMD) is a devastating disease characterized by progressive muscle wasting that leads to diminished lifespan. In addition to the inherent weakness of dystrophi...
onlinelibrary.wiley.com
December 26, 2024 at 4:31 PM
December is filled with exciting news! 🔬
🚨PUBLICATION ALERT🚨
"Wnt7a is required for regeneration of dystrophic skeletal muscle by Uxia Gurriaran-Rodriguez et al."

skeletalmusclejournal.biomedcentral.com/articles/10....
Wnt7a is required for regeneration of dystrophic skeletal muscle - Skeletal Muscle
Intramuscular injection of Wnt7a has been shown to accelerate and augment skeletal muscle regeneration and to ameliorate dystrophic progression in mdx muscle, a model for Duchenne muscular dystrophy (...
skeletalmusclejournal.biomedcentral.com
December 20, 2024 at 10:55 PM
🚨PUBLICATION ALERT🚨

Newest paper from our lab 🎉: "Identification of the Wnt signal peptide that directs secretion on extracellular vesicles by Uxia Gurriaran-Rodriguez et al."

www.science.org/doi/10.1126/...
Identification of the Wnt signal peptide that directs secretion on extracellular vesicles
A signal peptide that directs Wnt secretion on EVs was identified, and the structural mechanism for this secretion elucidated.
www.science.org
December 11, 2024 at 9:51 PM
❄️ Rudnicki lab holiday lunch 2024 ❄️☃️
December 11, 2024 at 1:15 AM
Hot off the press!🔬
Many years of research in our lab have paved the way for a possible treatment of Duchenne Muscular Dystrophy.
ottawacitizen.com/news/local-n...
An Ottawa scientist's discovery offers rare hope for patients with devastating genetic disease
An Ottawa stem cell researcher's groundbreaking discovery offers rare hope for patients with the genetic disease.
ottawacitizen.com
November 27, 2024 at 10:04 PM