Sensory symptoms in FND are:
✅ Highly prevalent
✅ Diverse
✅ Often disabling
✅ Frequently persistent
✅ Poorly captured by traditional sensory testing
They should be routinely asked about and addressed.
They are a core feature of FND - not an afterthought.
Sensory symptoms in FND are:
✅ Highly prevalent
✅ Diverse
✅ Often disabling
✅ Frequently persistent
✅ Poorly captured by traditional sensory testing
They should be routinely asked about and addressed.
They are a core feature of FND - not an afterthought.
Some report limbs feeling “dead”, absent, or not belonging to them.
This mirrors disturbances seen in stroke and CRPS involving higher-level sensory integration networks.
Some report limbs feeling “dead”, absent, or not belonging to them.
This mirrors disturbances seen in stroke and CRPS involving higher-level sensory integration networks.
Reduced accuracy or confidence in sensing internal bodily signals may amplify or distort sensory experiences.
Reduced accuracy or confidence in sensing internal bodily signals may amplify or distort sensory experiences.
High rates of sensory hypersensitivity (sound/light/touch) overlap with migraine and autism-related sensory traits, which point to potential shared predictive processing mechanisms.
High rates of sensory hypersensitivity (sound/light/touch) overlap with migraine and autism-related sensory traits, which point to potential shared predictive processing mechanisms.
Cold extremities, swelling, and colour changes are not uncommon in motor-FND (e.g. functional dystonia), suggesting altered peripheral circulation (consistent with previous descriptions of overlap with complex regional pain syndrome #CRPS).
Cold extremities, swelling, and colour changes are not uncommon in motor-FND (e.g. functional dystonia), suggesting altered peripheral circulation (consistent with previous descriptions of overlap with complex regional pain syndrome #CRPS).
FND often co-occurs with conditions that cause sensory symptoms (e.g. radiculopathy, carpal tunnel syndrome, etc) which often act as predisposing or perpetuating factors for FND.
FND often co-occurs with conditions that cause sensory symptoms (e.g. radiculopathy, carpal tunnel syndrome, etc) which often act as predisposing or perpetuating factors for FND.
Many people experience sensory symptoms associated with panic (e.g. tingling, dizziness, hot/cold) without feeling anxious (“panic without panic”).
Autonomic arousal may be misinterpreted in some individuals.
Many people experience sensory symptoms associated with panic (e.g. tingling, dizziness, hot/cold) without feeling anxious (“panic without panic”).
Autonomic arousal may be misinterpreted in some individuals.
Experiences of depersonalisation/derealisation are common in motor-FND.
Reports of insensate limbs or unnoticed injuries suggest impaired integration of sensory signals, consistent with the concept of compartmentalisation.
Experiences of depersonalisation/derealisation are common in motor-FND.
Reports of insensate limbs or unnoticed injuries suggest impaired integration of sensory signals, consistent with the concept of compartmentalisation.
Sensory and motor symptoms may be mutually consequential - two sides of the same coin.
These two processes are intrinsically linked and processed together within the brain. Improving one may result in improvement in the other.
Sensory and motor symptoms may be mutually consequential - two sides of the same coin.
These two processes are intrinsically linked and processed together within the brain. Improving one may result in improvement in the other.
Potential mechanistic explanations:
Potential mechanistic explanations:
Exploring what patients mean by their words is crucial in assessment.
Exploring what patients mean by their words is crucial in assessment.
Only one-third of motor-FND reported improvement in sensory symptoms at 12 months.
Only one-third of motor-FND reported improvement in sensory symptoms at 12 months.
Self-reported hypersensitivity was more common in FND (to light 63% FND vs 20% stroke; sound 65% FND vs 15% stroke).
Self-reported hypersensitivity was more common in FND (to light 63% FND vs 20% stroke; sound 65% FND vs 15% stroke).
These signs may still hold value as part of the accumulation of evidence in making a diagnosis.
Clinical context is important.
These signs may still hold value as part of the accumulation of evidence in making a diagnosis.
Clinical context is important.
Added little information to assessment.
Often detected abnormalities patients didn’t report.
Added little information to assessment.
Often detected abnormalities patients didn’t report.
Complete sensory loss in an area?
• 27% of motor-FND vs 11% stroke
Classic “glove and stocking” patterns?
• 20% of motor-FND vs 3% of stroke
Complete sensory loss in an area?
• 27% of motor-FND vs 11% stroke
Classic “glove and stocking” patterns?
• 20% of motor-FND vs 3% of stroke
While both groups reported numbness, people with motor-FND described a broader spectrum including: “dead” or an absent limb (19% motor-FND vs 1% stroke).
This is not a rare phenomenon for people with motor-FND.
While both groups reported numbness, people with motor-FND described a broader spectrum including: “dead” or an absent limb (19% motor-FND vs 1% stroke).
This is not a rare phenomenon for people with motor-FND.
When asked to list symptoms...
70% of motor-FND reported sensory symptoms without prompting.
96% endorsed them after prompting.
That’s higher than stroke (31% unprompted, 67% prompted).
When asked to list symptoms...
70% of motor-FND reported sensory symptoms without prompting.
96% endorsed them after prompting.
That’s higher than stroke (31% unprompted, 67% prompted).
Our new prospective case-control study compares sensory symptoms of 102 people with motor-FND vs 75 people with recent #stroke.
Here’s what we found 🧵
Our new prospective case-control study compares sensory symptoms of 102 people with motor-FND vs 75 people with recent #stroke.
Here’s what we found 🧵