Rong Ye
rong-ye.bsky.social
Rong Ye
@rong-ye.bsky.social
Chemistry PhD Candidate at Dong Group, UChicago
Reposted by Rong Ye
Our latest achievement is now online in Tetrahedron Letters, published as part of a special issue honoring Prof. Song Lin @songlin1.bsky.social for receiving the Tetrahedron Young Investigator Award.
sciencedirect.com/science/arti...
Congratulations to Xin and all co-authors!
Advances in vicinal dicarbo-C–H-functionalization of five-membered heteroarenes via palladium/norbornene cooperative catalysis
Direct introduction of two carbon substituents to less functionalized aromatic cores has been an attractive objective for late-stage modification and …
sciencedirect.com
July 23, 2025 at 6:44 PM
Reposted by Rong Ye
Last weekend, we had a wonderful farewell party for Congjun and Miao at Guangbin's house.
Congjun will join UC Boulder as a tenure-track Assistant Professor, and Miao will be starting at Merck as a Senior Scientist.
Wishing them both the best of luck!
July 8, 2025 at 5:55 PM
Reposted by Rong Ye
Proud to add one more reagent to EROS!
In this article, we summarized the synthesis and application of the N-methylbicyclo[2.2.1]hept-2-ene-2-carboxamide, a co-catalyst in the palladium/norbornene cooperative catalysis.
Congrats to Dr. Shinyoung Choi!
onlinelibrary.wiley.com/doi/10.1002/...
N‐methylbicyclo[2.2.1]hept‐2‐ene‐2‐carboxamide
[2394994-09-1] C9H13NO (MW 151.21) InChI = 1S/C9H13NO/c1-10-9(11)8-5-6-2-3-7(8)4-6/h5-7H,2-4H2,1H3,(H,10,11) InChIKey = BYXAMVZFVXOYIF-UHFFFAOYSA-N (reagent used as a co-catalyst...
onlinelibrary.wiley.com
July 3, 2025 at 7:13 PM
Reposted by Rong Ye
🚀New advance toward asymmetric α‑Alkylation of Aldehydes.
✨Lead by Kezhi, we report a branched-selective α-alkylation of aldehydes with unactivated olefins — enabled by a pyrazole mediator and a chiral Ir catalyst. Congrats!
pubs.acs.org/doi/full/10....
Toward Iridium-Catalyzed Asymmetric Branched-Selective α-Alkylation of Aldehydes with Unactivated Alkenes Enabled by a Pyrazole Mediator
Aldehyde α-alkylation remains a challenging transformation. On the other hand, given the wide availability of alkenes, it has been an attractive objective to use unactivated alkenes as alkylating agen...
pubs.acs.org
June 25, 2025 at 6:49 PM
Reposted by Rong Ye
🔥 Scalable achievement in enantioselective homologation.
🔥 Our work on "Enantioconvergent carbenoid insertion into carbon−boron bonds" is now online on Nature Synthesis rdcu.be/etopg
🎉Congratulations to Qiqiang!
🙏Thanks to our collaborator Liu group
Enantioconvergent carbenoid insertion into carbon–boron bonds
Nature Synthesis - An enantioconvergent approach for direct asymmetric insertion of racemic carbon-, oxygen-, nitrogen-, sulfur- and silicon-substituted carbenoids into carbon–boron bonds is...
rdcu.be
June 25, 2025 at 6:50 PM
Reposted by Rong Ye
🚨Just out in Nature!
We have offered a general method for 1,2-difunctionlization of arenes via a differential 1,2-diborylation!
rdcu.be/esXq8
www.nature.com/articles/s41...
Congratulations to Jingfeng!
June 23, 2025 at 9:59 PM
Reposted by Rong Ye
Out First Release in @science.org today, Zining Zhang in @donglab.bsky.social swaps out ketones for sulfur in saturated carbon rings through two modes of radical trapping www.science.org/doi/10.1126/...
Carbonyl-to-sulfur swap enabled by sequential double carbon-carbon bond activation
In drug development, replacement of a skeletal carbon with a sulfur atom can result in analogs of bioactive compounds with improved properties. Currently, the sulfur analogs are almost exclusively pre...
www.science.org
June 12, 2025 at 7:04 PM
Reposted by Rong Ye
How do you turn a carbonyl into sulfur?

In this work, Zining from our lab developed a carbonyl-to-sulfur swap enabled by a rationally designed N′-alkyl-hydrazonamide (NAHA) reagent that promotes double C-C bond activation.

www.science.org/doi/10.1126/...
June 12, 2025 at 9:13 PM
Reposted by Rong Ye
Thrilled to share our latest achievement in C-C activation: Downsizing lactams via Rh-catalyzed C-C activation.
www.sciencedirect.com/science/arti...
Congratulations to Rui and Kangmin!
Downsizing lactams via Rh-catalyzed C–C activation
Ring-contraction reactions are valuable transformations to access harder-to-synthesize smaller-sized rings from more-available larger-sized precursors…
www.sciencedirect.com
June 10, 2025 at 7:08 PM