Ronan Doyle
banner
ronandoyle.bsky.social
Ronan Doyle
@ronandoyle.bsky.social
Clinical bioinformatician at St Thomas' Hospital in London, UK (Synnovis).

Working on infectious disease diagnostics. Pathogen genomics and metagenomics.
The new version of the protocol can be found at: www.protocols.io/view/pan-mic...

A big thank you for all the hard work from all sites involved! (3/3)
Pan-microbial metagenomics protocol v1.2
Version 1.2 of the pan-microbial metagenomics protocol enhances the depletion of human DNA in clinical samples and improves the detection of microorganisms and resistance genes....
www.protocols.io
October 20, 2025 at 10:35 AM
It is an improvement on the method that has been used in botho ur single-centre ICU paper published last month in Lancet Microbe, and the preprint results reported by GOSH in their paediatric intensive care setting:

www.thelancet.com/journals/lan...

www.medrxiv.org/content/10.1...

(2/3)
Rapid pan-microbial metagenomics for pathogen detection and personalised therapy in the intensive care unit: a single-centre prospective observational study
Respiratory metagenomics for ICU patients showed good performance and turnaround time, and diverse clinical and public health benefits. This ability to inform both personalised patient therapy and inf...
www.thelancet.com
October 20, 2025 at 10:35 AM
Reposted by Ronan Doyle
Next speaker was Luke Blagdon Snell with Same-day pan-microbial metagenomics for personalized therapy and pathogen surveillance on the intensive care unit: a single-centre prospective study (escmid.reg.key4events.com/AbstractList...).
Same-day pan-microbial metagenomics for personalised therapy and pathogen surveillance on the intensive care unit: a single-centre prospective study
escmid.reg.key4events.com
April 13, 2025 at 4:03 AM
Reposted by Ronan Doyle
Robbie Hammond presented next with Implementing same-day respiratory metagenomic diagnostics in paediatric intensive care (escmid.reg.key4events.com/AbstractList...). Their method had a turnaround time of 6 hours.
Implementing same-day respiratory metagenomic diagnostics in paediatric intensive care
escmid.reg.key4events.com
April 13, 2025 at 4:03 AM