Romain Barthélémy
@rombarthelemy.bsky.social
ICU physician, Hôpital Lariboisière, Paris, France
#Hemodynamics #Monitoring #Echo #AcuteBrainInjury #CriticalCare #NeuroCriticalCare #Physiology #Rstats
#Hemodynamics #Monitoring #Echo #AcuteBrainInjury #CriticalCare #NeuroCriticalCare #Physiology #Rstats
Therefore, yes. There is a separate effect in hypoxia with vasodilators: one from impairment of HPV and one from the increase in CO
November 17, 2025 at 10:11 AM
Therefore, yes. There is a separate effect in hypoxia with vasodilators: one from impairment of HPV and one from the increase in CO
If PaO2 increase with PEEP but CO decrease, it’s not alveolar recruitment
We most recently tried to highlight this in this paper
pubmed.ncbi.nlm.nih.gov/33223045/
We most recently tried to highlight this in this paper
pubmed.ncbi.nlm.nih.gov/33223045/
Haemodynamic impact of positive end-expiratory pressure in SARS-CoV-2 acute respiratory distress syndrome: oxygenation versus oxygen delivery - PubMed
Haemodynamic impact of positive end-expiratory pressure in SARS-CoV-2 acute respiratory distress syndrome: oxygenation versus oxygen delivery
pubmed.ncbi.nlm.nih.gov
November 17, 2025 at 10:08 AM
If PaO2 increase with PEEP but CO decrease, it’s not alveolar recruitment
We most recently tried to highlight this in this paper
pubmed.ncbi.nlm.nih.gov/33223045/
We most recently tried to highlight this in this paper
pubmed.ncbi.nlm.nih.gov/33223045/
There’s an impact of change in CO on Qs/Qt, it has been known for decades and the same magnitude of effect is observed whether CO is manipulated pharmacologically or mechanically
pubmed.ncbi.nlm.nih.gov/422447/
pubmed.ncbi.nlm.nih.gov/422447/
Influence of cardiac output on intrapulmonary shunt - PubMed
The effect of changing cardiac output on intrapulmonary shunt was studied in the setting of hemorrhagic pulmonary edema induced by intravenous oleic acid in 17 alpha-chloralose-anesthetized dogs. The dogs were mechanically ventilated and cardiac output was alternately depressed and augmented using e …
pubmed.ncbi.nlm.nih.gov
November 17, 2025 at 10:08 AM
There’s an impact of change in CO on Qs/Qt, it has been known for decades and the same magnitude of effect is observed whether CO is manipulated pharmacologically or mechanically
pubmed.ncbi.nlm.nih.gov/422447/
pubmed.ncbi.nlm.nih.gov/422447/
In the case of milrinone used in treatment of cerebral vasospam following SAH, we observed an increase in hypoxemia as well as an increase in CO
pubmed.ncbi.nlm.nih.gov/38579430/
pubmed.ncbi.nlm.nih.gov/38579430/
Systemic tolerance of intravenous milrinone administration for cerebral vasospasm secondary to non-traumatic subarachnoid hemorrhage - PubMed
Intravenous milrinone for CVS treatment seems associated with significant impact on systemic hemodynamics leading sometimes to treatment discontinuation.
pubmed.ncbi.nlm.nih.gov
November 17, 2025 at 9:06 AM
In the case of milrinone used in treatment of cerebral vasospam following SAH, we observed an increase in hypoxemia as well as an increase in CO
pubmed.ncbi.nlm.nih.gov/38579430/
pubmed.ncbi.nlm.nih.gov/38579430/
Pure vasodilators might decrease hypoxic pulmonary vasodilation, but in the case of inodilators (milrinone), the increase in CO will lead to an increase in Qs/Qt
November 17, 2025 at 9:04 AM
Pure vasodilators might decrease hypoxic pulmonary vasodilation, but in the case of inodilators (milrinone), the increase in CO will lead to an increase in Qs/Qt
I think the appropriate outcome is still undefined
December 15, 2024 at 1:53 PM
I think the appropriate outcome is still undefined
I can't believe it doesn't change the prognosis for survivors (which is the only real patient-centered outcome).
December 10, 2024 at 11:27 AM
I can't believe it doesn't change the prognosis for survivors (which is the only real patient-centered outcome).