Congrats Ish! Well deserved.

Congrats Sebastian!

Outstanding

Huge losses across the board - but for the US pain research and treatment community in particular this is a dark day.

We acknowledge and greatly appreciate financial support from the National Institutes of Health. Not only for the direct funding of this work, but for funding decades of foundational work that forms the knowledge base that enabled these recent advances. Without NIH funding this wouldn't have happened

This new class of agonists shows signaling bias, substantially improved peripheral restriction compared to previously reported "peripherally-restricted" CB1 ligands. The result is a dramatic reduction in analgesic tolerance and unwanted CNS-mediated side effects.

Led by the lab of Sush Majumdar, we worked with labs of Ron Dror, Kaavya Krishna Kumar, Michael Cameron, Amynhah Pradhan and Bryan Kobilka to develop a next-generation cannabinoid CB1 agonist

Such an honor to get to work with this incredible group of humans. gereaulab.wustl.edu/people-page/