Antoine Rimbert
@rimbert-a.bsky.social
Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...
Robust pleiotropy-decomposed polygenic scores identify distinct contributions to elevated coronary artery disease polygenic risk
Author summary Aggregating genetic variants into a polygenic risk score (PRS) can predict an individual’s risk for complex diseases such as coronary artery disease (CAD). However, people with high PRS...
dx.plos.org
July 1, 2025 at 7:38 AM
Checkout this article I found at PLOS: dx.plos.org/10.1371/jour...
Commander complex regulates lysosomal function and is implicated in Parkinson’s disease risk | Science www.science.org/doi/10.1126/...
Commander complex regulates lysosomal function and is implicated in Parkinson’s disease risk
Variants in GBA1 resulting in decreased lysosomal glucocerebrosidase (GCase) activity are a common risk factor for Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Incomplete penetrance o...
www.science.org
April 11, 2025 at 4:19 AM
Commander complex regulates lysosomal function and is implicated in Parkinson’s disease risk | Science www.science.org/doi/10.1126/...
JCI - Human genetics of metabolic dysfunction–associated steatotic liver disease: from variants to cause to precision treatment www.jci.org/articles/vie...
JCI -
Human genetics of metabolic dysfunction–associated steatotic liver disease: from variants to cause to precision treatment
www.jci.org
April 7, 2025 at 1:40 PM
JCI - Human genetics of metabolic dysfunction–associated steatotic liver disease: from variants to cause to precision treatment www.jci.org/articles/vie...
Long-term body mass index trajectories and the risk of type 2 diabetes mellitus and atherosclerotic cardiovascular disease using healthcare data from UK Biobank participants - Atherosclerosis www.atherosclerosis-journal.com/article/S002...
Long-term body mass index trajectories and the risk of type 2 diabetes mellitus and atherosclerotic cardiovascular disease using healthcare data from UK Biobank participants
Most epidemiological studies ignore long-term burden, gain and variability in body
weight in assessing cardiometabolic disease risk. We investigated the associations
of body mass index (BMI) trajector...
www.atherosclerosis-journal.com
April 1, 2025 at 5:30 AM
Long-term body mass index trajectories and the risk of type 2 diabetes mellitus and atherosclerotic cardiovascular disease using healthcare data from UK Biobank participants - Atherosclerosis www.atherosclerosis-journal.com/article/S002...
ER nests are specialized ER subdomains in Arabidopsis where peroxisomes and lipid droplets form: Developmental Cell www.cell.com/developmenta...
ER nests are specialized ER subdomains in Arabidopsis where peroxisomes and lipid droplets form
Wright et al. used live-cell fluorescence microscopy of Arabidopsis seedlings stably
transformed with various reporter constructs to identify discrete ER domains (ER nests)
where peroxisomes and lipid...
www.cell.com
April 1, 2025 at 5:20 AM
ER nests are specialized ER subdomains in Arabidopsis where peroxisomes and lipid droplets form: Developmental Cell www.cell.com/developmenta...