Richa Shah
@richashah.bsky.social
Cancer researcher, Lab manager. Committed to translating research findings into cancer treatments.
Excited to share our new research article from Sidi Lab @sidilab.bsky.social Here we show how step-wise phosphorylation and SUMOylation of PIDD1 help in the maintenance of PIDDosome assembly! Thanks to everyone who made it possible!
Here’s the link: www.nature.com/articles/s41...
Here’s the link: www.nature.com/articles/s41...
Stepwise phosphorylation and SUMOylation of PIDD1 drive PIDDosome assembly in response to DNA repair failure - Nature Communications
After DNA damage a caspase-2 activating PIDDosome can be formed. Here the authors identify sequential post-translational modifications of PIDD1 which orchestrate PIDDosome formation in space and time.
www.nature.com
January 30, 2025 at 1:49 AM
Excited to share our new research article from Sidi Lab @sidilab.bsky.social Here we show how step-wise phosphorylation and SUMOylation of PIDD1 help in the maintenance of PIDDosome assembly! Thanks to everyone who made it possible!
Here’s the link: www.nature.com/articles/s41...
Here’s the link: www.nature.com/articles/s41...