@riccardobrambilla.bsky.social
Professor of Neuroscience and Neuropsychopharmacology. Interested in developing therapeutics for Neurodevelopmental Disorders and Neurodegenerative Diseases
Reposted
Exciting news! Our most important work is out as preprint!
We suggest sildenafil as a treatment for mitochondrial disease Leigh syndrome, from stem and organoid model to mice and off-label use.
Next step is the clinical trial starting early next year!
www.medrxiv.org/content/10.1...
We suggest sildenafil as a treatment for mitochondrial disease Leigh syndrome, from stem and organoid model to mice and off-label use.
Next step is the clinical trial starting early next year!
www.medrxiv.org/content/10.1...
Pluripotent stem cell-based drug discovery uncovers sildenafil as a treatment for mitochondrial disease
Mitochondrial disease encompasses inherited disorders affecting mitochondrial function. A severe and untreatable form of mitochondrial disease is Leigh syndrome (LS) causing psychomotor regression and...
www.medrxiv.org
May 19, 2025 at 12:19 PM
Exciting news! Our most important work is out as preprint!
We suggest sildenafil as a treatment for mitochondrial disease Leigh syndrome, from stem and organoid model to mice and off-label use.
Next step is the clinical trial starting early next year!
www.medrxiv.org/content/10.1...
We suggest sildenafil as a treatment for mitochondrial disease Leigh syndrome, from stem and organoid model to mice and off-label use.
Next step is the clinical trial starting early next year!
www.medrxiv.org/content/10.1...
Reposted
Regional differences in progenitor metabolism shape brain growth during development: Cell www.cell.com/cell/fulltex...
Regional differences in progenitor metabolism shape brain growth during development
Brain-wide birthdate mapping reveals that while hindbrain neurogenesis is transient,
forebrain neurogenesis is temporally sustained through spatiotemporal regulation of
progenitor mitochondrial functi...
www.cell.com
May 2, 2025 at 11:10 AM
Regional differences in progenitor metabolism shape brain growth during development: Cell www.cell.com/cell/fulltex...
Reposted
We are hiring!
@aurinaarn.bsky.social and I are jointly looking for a talented Postdoc in Systems and Comp Neuro at Monash (AUS).
If you like neuroimaging 🧠, comp models 💻, genetics 🧬, brain disorders 🤕, and/or evolution 🐵🐭, this could be the job for you!!
careers.pageuppeople.com/513/cw/en/jo...
@aurinaarn.bsky.social and I are jointly looking for a talented Postdoc in Systems and Comp Neuro at Monash (AUS).
If you like neuroimaging 🧠, comp models 💻, genetics 🧬, brain disorders 🤕, and/or evolution 🐵🐭, this could be the job for you!!
careers.pageuppeople.com/513/cw/en/jo...
Job Search
careers.pageuppeople.com
April 17, 2025 at 4:33 AM
We are hiring!
@aurinaarn.bsky.social and I are jointly looking for a talented Postdoc in Systems and Comp Neuro at Monash (AUS).
If you like neuroimaging 🧠, comp models 💻, genetics 🧬, brain disorders 🤕, and/or evolution 🐵🐭, this could be the job for you!!
careers.pageuppeople.com/513/cw/en/jo...
@aurinaarn.bsky.social and I are jointly looking for a talented Postdoc in Systems and Comp Neuro at Monash (AUS).
If you like neuroimaging 🧠, comp models 💻, genetics 🧬, brain disorders 🤕, and/or evolution 🐵🐭, this could be the job for you!!
careers.pageuppeople.com/513/cw/en/jo...
Reposted
Excited to share that our latest review on how environmental factor and molecular pathways shape personality disorders is now highlighted on @psypost.bsky.social!
Read the full text here: doi.org/10.1016/j.ne...
#PsychiatricResearch #RasERK #mTOR #MitochondrialDysfunction #OxidativeStress
Read the full text here: doi.org/10.1016/j.ne...
#PsychiatricResearch #RasERK #mTOR #MitochondrialDysfunction #OxidativeStress
Scientists explore molecular links between stress, brain function, and personality disorders
A recent review highlights how stress, trauma, and environment may biologically rewire the brain in people with personality disorders.
www.psypost.org
April 15, 2025 at 3:00 PM
Excited to share that our latest review on how environmental factor and molecular pathways shape personality disorders is now highlighted on @psypost.bsky.social!
Read the full text here: doi.org/10.1016/j.ne...
#PsychiatricResearch #RasERK #mTOR #MitochondrialDysfunction #OxidativeStress
Read the full text here: doi.org/10.1016/j.ne...
#PsychiatricResearch #RasERK #mTOR #MitochondrialDysfunction #OxidativeStress