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renardlab.bsky.social
Renard Lab
@renardlab.bsky.social
37 followers 18 following 16 posts
Data Analytics and Computational Statistics research group @HPI ✨ Account run by Prof. Bernhard Renard, Yannick Hartmaring, and Ferdous Nasri.
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Reposted by Renard Lab
pascivers.bsky.social
Despite hundreds of published models for cancer drug response prediction, none are used in clinical practice.

Why?

In our preprint, we outline key challenges and introduce a living benchmark to help the field move forward.

Check out the thread by my co–first author @judith-bernett.bsky.social:
judith-bernett.bsky.social Judith Bernett @judith-bernett.bsky.social · Jun 3
🧬🖥️So excited to show you the outcome of @pascivers.bsky.social and my latest project: "From Hype to Health Check: Critical Evaluation of Drug Response Prediction Models with DrEval" doi.org/10.1101/2025.05.26.655288, published with M. Picciani, M. Wilhelm, K. Baum & @itisalist.bsky.social.
🧵1/10
Overview of the DrEval framework. Via input options, implemented state-of-the-art models can be compared against baselines of varying complexity. We address obstacles to progress in the field at each point in our pipeline: Our framework is available on PyPI and nf-core and we follow FAIReR standards for optimal reproducibility. DrEval is easily extendable as demonstrated here with a pseudocode implementation of a proteomics-based random forest. Custom viability data can be preprocessed with CurveCurator, leading to more consistent data and metrics. DrEval supports five widely used datasets with application-aware train/test splits that enable detecting weak generalization. Models are free to use provided or custom cell line– and drug features. The pipeline supports randomization-based ablation studies and performs robust hyperparameter tuning for all models. Evaluation is conducted using meaningful, bias-resistant metrics to avoid inflated results from artifacts such as Simpson’s paradox. All results are compiled into an interactive HTML report. Created in https://BioRender.com.
June 3, 2025 at 2:58 PM
renardlab.bsky.social
What a run! 🏃‍♀️🏃‍♂️
Last week, our group took part in the Berlin #Firmenlauf, and we had an amazing time out there, running, cheering each other on, and just enjoying the energy of the event! #TeamVibes

Thanks to everyone who made it such a memorable day 🤗 #ScienceInSneakers @hpi.bsky.social
@y.hartmar
May 30, 2025 at 9:39 AM
Reposted by Renard Lab
helenekretzmer.bsky.social
We’re excited to share that our paper on rapid molecular classification of brain tumors has just been published in Nature Medicine!
March 2, 2025 at 4:01 PM
renardlab.bsky.social
We're proud to have Akin present his ongoing master's thesis project at the European Crohn's and Colitis Organisation (ECCO)
Congress 2025!
Akin joyously standing in front of his poster titled “Morning administration of biological therapy is associated with decreased risk of treatment failure in patients with Inflammatory Bowel Disease” at the European Crohn’s and Colitis Organisation (ECCO) congress!
March 6, 2025 at 7:48 AM
renardlab.bsky.social
Check out the awesome opportunity to join the group of one of the brilliant minds at our chair!
jmbartoszewicz.bsky.social Jakub Bartoszewicz @jmbartoszewicz.bsky.social · Feb 11
I'm setting up my lab at @hpi.bsky.social, on the edge of vibrant Berlin! PhD/postdoc positions in AI for safe synthetic biology & infectious diseases (AMR), in collab with @melanianowicka.bsky.social.

Apply by Feb 24: email firstname.lastname@hpi.de with “[Open-25]” in the subject. DM for details!
February 11, 2025 at 1:05 PM
renardlab.bsky.social
Ferdous Nasri presenting her work on the 'Spatio-temporal immunity index tool for infectious diseases' at the Digital Health Summit at University of Cape Town in South Africa!
Ferdous smiling in front of her poster.
February 7, 2025 at 4:33 PM
renardlab.bsky.social
💐Congratulations to ✨ Dr. Susanne Ibing! 🎓

Susanne, @sibing.bsky.social, successfully defended her doctoral dissertation @hpi.bsky.social this month on “Computational Strategies for Chronic Disease Characterization and Treatment by Leveraging Electronic Health Records and Omics Data” 🩻🧬👩🏼‍💻
Dr. Susanne Ibing joyously shaking hands with Prof. Bernhard Renard! Susanne defends her dissertation in front of the fully-packed room. Dr. Susanne standing proudly wearing her graduation hat and robe in front of the HPI Digital Health building smiling with all the people that participated in her dissertation defence.
January 31, 2025 at 3:02 PM
renardlab.bsky.social
New paper: Electronic Health Records-Based Identification of Newly Diagnosed Crohn’s Disease Cases

By Susanne Ibing @sibing.bsky.social , Julian Hugo, et al., now available in Artificial Intelligence in Medicine.

authors.elsevier.com/a/1kA113KEGa...

🧵 1/6 Thread below:
authors.elsevier.com
January 2, 2025 at 2:53 PM
renardlab.bsky.social
Happy New Year and a warm hello world from our group! 🥳😄
Picture of the group members smiling standing in a meeting room facing the camera.
January 2, 2025 at 2:07 PM