Reinier de Vries
@reinierdevries.bsky.social
PhD student in the Computational Biomolecular Dynamics group at the Max Planck Institute for Multidisciplinary Sciences | Molecular Dynamics | Potassium Channels
We identify two distinct binding sites in the MthK cavity. We show that binding of Ca2+ to the upper binding site, below the SF, near Phe87, blocks K+ permeation and that this binding is voltage dependent. Ca2+ only binds here under positive voltage, permeation under negative voltage is unaffected.
August 19, 2025 at 7:49 AM
We identify two distinct binding sites in the MthK cavity. We show that binding of Ca2+ to the upper binding site, below the SF, near Phe87, blocks K+ permeation and that this binding is voltage dependent. Ca2+ only binds here under positive voltage, permeation under negative voltage is unaffected.
Reposted by Reinier de Vries
Poster Session #bps2025 on Sunday, February 16 starting at 1:45 pm in the West Exhibit Hall including posters of Aaron, Sara @saragabrielli.bsky.social, Ole, Bartosz, Chen, Reinier
plan.core-apps.com/bpsam2025/ev...
plan.core-apps.com/bpsam2025/ev...
February 14, 2025 at 2:09 PM
Poster Session #bps2025 on Sunday, February 16 starting at 1:45 pm in the West Exhibit Hall including posters of Aaron, Sara @saragabrielli.bsky.social, Ole, Bartosz, Chen, Reinier
plan.core-apps.com/bpsam2025/ev...
plan.core-apps.com/bpsam2025/ev...