Ravi Radhakrishnan
@ravi-radhak.bsky.social
Science, Engineering, Medicine Nerd, Outdoors, Travel, Art Enthusiast, Husband, Parent of 3 children (two 2-legged and one 4-legged)
Excited and grateful to @upenn.edu Engineers for covering our lab!
blog.seas.upenn.edu/penn-enginee...
blog.seas.upenn.edu/penn-enginee...
Penn Engineers Explore How Tumor Mechanics and Tiny Messengers Could Shape the Future of Cancer Research - Penn Engineering Blog
When Ph.D. student Kshitiz Parihar began combing through dozens of research papers on two seemingly different topics — tumor mechanics and extracellular vesicles, tiny packages … Read More ›
blog.seas.upenn.edu
September 20, 2025 at 3:41 AM
Excited and grateful to @upenn.edu Engineers for covering our lab!
blog.seas.upenn.edu/penn-enginee...
blog.seas.upenn.edu/penn-enginee...
Reposted by Ravi Radhakrishnan
Online today!
Wei Guo and team show that, in response to CAR T cell targeting, solid tumors increase the secretion of small extracellular vesicles carrying tumor antigens that are transferred to CAR T cells, resulting in fratricide and reduced antitumor activity.
www.nature.com/articles/s43...
Wei Guo and team show that, in response to CAR T cell targeting, solid tumors increase the secretion of small extracellular vesicles carrying tumor antigens that are transferred to CAR T cells, resulting in fratricide and reduced antitumor activity.
www.nature.com/articles/s43...
Overcoming extracellular vesicle-mediated fratricide improves CAR T cell treatment against solid tumors - Nature Cancer
Zhong et al. show that, in response to chimeric antigen receptor (CAR) T cell targeting, solid tumors increase the secretion of small extracellular vesicles carrying tumor antigens that are transferre...
www.nature.com
April 15, 2025 at 9:41 AM
Online today!
Wei Guo and team show that, in response to CAR T cell targeting, solid tumors increase the secretion of small extracellular vesicles carrying tumor antigens that are transferred to CAR T cells, resulting in fratricide and reduced antitumor activity.
www.nature.com/articles/s43...
Wei Guo and team show that, in response to CAR T cell targeting, solid tumors increase the secretion of small extracellular vesicles carrying tumor antigens that are transferred to CAR T cells, resulting in fratricide and reduced antitumor activity.
www.nature.com/articles/s43...