🗓️ October 28, 12pm EST
Join us for a Space on Tropical AKI, Part 2
🎧 Set your reminder twitter.com/i/spaces/1gq...
🧠 Before the session, test your knowledge!
Take the quiz 👉 theisn.outgrow.us/Tropical_AKI
Let’s see how much you know about Tropical AKI before the experts dive in! 💪🌴
🗓️ October 28, 12pm EST
Join us for a Space on Tropical AKI, Part 2
🎧 Set your reminder twitter.com/i/spaces/1gq...
🧠 Before the session, test your knowledge!
Take the quiz 👉 theisn.outgrow.us/Tropical_AKI
Let’s see how much you know about Tropical AKI before the experts dive in! 💪🌴
🔆Happy to contribute in this #videoabstract
🎉Thank you @theisn.org and @dilushiwijay.bsky.social for the opportunity
@myadla.bsky.social @arvindcanchi.bsky.social
By @kajareeg.bsky.social & @dilushiwijay.bsky.social
🔆Happy to contribute in this #videoabstract
🎉Thank you @theisn.org and @dilushiwijay.bsky.social for the opportunity
@myadla.bsky.social @arvindcanchi.bsky.social
May have renoprotective effects as per their molecular mechanism, but the evidence to date applies only to heart failure.
Future studies in CKD are needed, perhaps? 🤔
May have renoprotective effects as per their molecular mechanism, but the evidence to date applies only to heart failure.
Future studies in CKD are needed, perhaps? 🤔
They reduce HF hospitalisations, preserve GFR, slow CKD progression and improve outcomes in CRS.
🔹 Trials: DAPA-HF, EMPA-KIDNEY show mortality & renal benefits.
Do check out the link for the new SGLT2i toolkit there: theisn.org/initiatives/...
They reduce HF hospitalisations, preserve GFR, slow CKD progression and improve outcomes in CRS.
🔹 Trials: DAPA-HF, EMPA-KIDNEY show mortality & renal benefits.
Do check out the link for the new SGLT2i toolkit there: theisn.org/initiatives/...
doi.org/10.1161/CIRC...
doi.org/10.1161/CIRC...
🔹 Loop diuretics = cornerstone
🔹 Use high doses for diuretic resistance; consider thiazides for synergy.
🔹 UF for refractory cases, but monitor renal function closely.
🔹 Aggressive diuresis improves outcomes even with transient ↑ creatinine.
🔹 Loop diuretics = cornerstone
🔹 Use high doses for diuretic resistance; consider thiazides for synergy.
🔹 UF for refractory cases, but monitor renal function closely.
🔹 Aggressive diuresis improves outcomes even with transient ↑ creatinine.
1️⃣ Decongestion (diuretics/ultrafiltration).
2️⃣ Neurohormonal modulation (RAASI, SGLT2i).
3️⃣ Volume assessment (CVP, intrarenal Doppler).
4️⃣ Treat underlying systemic disease (e.g., sepsis).
5️⃣ Multidisciplinary care
doi.org/10.3390/hear...
1️⃣ Decongestion (diuretics/ultrafiltration).
2️⃣ Neurohormonal modulation (RAASI, SGLT2i).
3️⃣ Volume assessment (CVP, intrarenal Doppler).
4️⃣ Treat underlying systemic disease (e.g., sepsis).
5️⃣ Multidisciplinary care
doi.org/10.3390/hear...
CRS management is about balance. It’s a tightrope walk between relieving congestion & preserving renal function. Let’s talk strategies.
Here is the strategy for acute cases, doi.org/10.3390/hear...
CRS management is about balance. It’s a tightrope walk between relieving congestion & preserving renal function. Let’s talk strategies.
Here is the strategy for acute cases, doi.org/10.3390/hear...
doi.org/10.3390/jpm1...
doi.org/10.3390/jpm1...
Here is a list
Here is a list
We look at:
Biomarkers: NT-proBNP, cystatin C, NGAL, KIM-1
Imaging: Echo (CVP, LVEF), renal US (exclude obstruction)
Volume status: Clinical exam + POCUS
We look at:
Biomarkers: NT-proBNP, cystatin C, NGAL, KIM-1
Imaging: Echo (CVP, LVEF), renal US (exclude obstruction)
Volume status: Clinical exam + POCUS
For years, we thought hypoperfusion drove CRS.
🔥Turns out, congestion is the bigger villain. High venous pressure, intra-abdominal pressure (IAP), and renal compression all hurt GFR.
doi.org/10.3389/fphy...
For years, we thought hypoperfusion drove CRS.
🔥Turns out, congestion is the bigger villain. High venous pressure, intra-abdominal pressure (IAP), and renal compression all hurt GFR.
doi.org/10.3389/fphy...
—it’s a cocktail of mechanisms: 🩺
Central players:
Congestion → ↓ Renal perfusion
RAAS & SNS activation → Maladaptive changes
Inflammation & oxidative stress → Organ damage
doi.org/10.1161/CIR....
—it’s a cocktail of mechanisms: 🩺
Central players:
Congestion → ↓ Renal perfusion
RAAS & SNS activation → Maladaptive changes
Inflammation & oxidative stress → Organ damage
doi.org/10.1161/CIR....
nature.com/articles/nrn...
Types of CRS:
1️⃣ Type I: Acute HF → AKI
2️⃣ Type II: Chronic HF → CKD
3️⃣ Type III: AKI → Acute HF
4️⃣ Type IV: CKD → Chronic HF
5️⃣ Type V: Systemic diseases (e.g., sepsis) → Combined dysfunction
nature.com/articles/nrn...
Types of CRS:
1️⃣ Type I: Acute HF → AKI
2️⃣ Type II: Chronic HF → CKD
3️⃣ Type III: AKI → Acute HF
4️⃣ Type IV: CKD → Chronic HF
5️⃣ Type V: Systemic diseases (e.g., sepsis) → Combined dysfunction
Did you know the heart & kidneys are so intertwined that dysfunction in one can wreak havoc on the other?
Let's dive into CRS today.
A lucid read for every nephrology & cardiology fellow 🫀🩺
#MedTwitter
#ISNTweetorial
Did you know the heart & kidneys are so intertwined that dysfunction in one can wreak havoc on the other?
Let's dive into CRS today.
A lucid read for every nephrology & cardiology fellow 🫀🩺
#MedTwitter
#ISNTweetorial
Join the ISN in raising awareness of IgA Nephropathy (#IgAN), a rare but impactful kidney disease.
📚 Explore the ISN's dedicated IgAN resources, all available through the Rare Kidney Diseases Toolkit: www.theisn.org/initiatives/...
Join the ISN in raising awareness of IgA Nephropathy (#IgAN), a rare but impactful kidney disease.
📚 Explore the ISN's dedicated IgAN resources, all available through the Rare Kidney Diseases Toolkit: www.theisn.org/initiatives/...
🔗 http://lite.spr.ly/6...
#ISNGKHA #WHA78 #KidneyHealthMatters #UHC
🔗 http://lite.spr.ly/6...
#ISNGKHA #WHA78 #KidneyHealthMatters #UHC
#Nephpearls #NephSky
🗓️ May 22
🕑 3:00 pm CEST
👉🏼 twitter.com/i/spaces/1jM...
#Nephpearls #NephSky
🗓️ May 22
🕑 3:00 pm CEST
👉🏼 twitter.com/i/spaces/1jM...
We're looking forward to what’s coming next, so stay tuned!
We're looking forward to what’s coming next, so stay tuned!
#VideoAbstract by @drsumanbehera.bsky.social
#VideoAbstract by @drsumanbehera.bsky.social
🧑🤝🧑1.3 billion people live with HTN, but only 1 in 5 meet BP goals.
⚠️HTN silently drives stroke, heart & kidney failure—and 57% of global deaths.
Check this beautiful Infographic by @gabyneph.bsky.social
#ISNTweetorial #WorldHypertensionDay
🧑🤝🧑1.3 billion people live with HTN, but only 1 in 5 meet BP goals.
⚠️HTN silently drives stroke, heart & kidney failure—and 57% of global deaths.
Check this beautiful Infographic by @gabyneph.bsky.social
#ISNTweetorial #WorldHypertensionDay
📌HTN remains the leading global contributor to reno cardiovascular death and disability.
📌Take this evidence-based quiz from ISN SoMe team members to assess your knowledge and improve patient care. Here’s the link for the quiz: theisn.outgrow.us/HTN_2025
📌HTN remains the leading global contributor to reno cardiovascular death and disability.
📌Take this evidence-based quiz from ISN SoMe team members to assess your knowledge and improve patient care. Here’s the link for the quiz: theisn.outgrow.us/HTN_2025
Since its launch, World Kidney Day has raised global awareness of kidney health. The 2025 campaign #AreYourKidneysOK highlights the importance of #EarlyDetection in preventing and managing kidney disease.
🔗 Learn more: www.worldkidneyday.o...
#KidneyHealthMatters
Since its launch, World Kidney Day has raised global awareness of kidney health. The 2025 campaign #AreYourKidneysOK highlights the importance of #EarlyDetection in preventing and managing kidney disease.
🔗 Learn more: www.worldkidneyday.o...
#KidneyHealthMatters
Get them checked! And spread kidney awareness! #WorldKidneyDay #NephSky #MedSky @theisn.org @sandhyasuresh.bsky.social @raphapalma.bsky.social
Get them checked! And spread kidney awareness! #WorldKidneyDay #NephSky #MedSky @theisn.org @sandhyasuresh.bsky.social @raphapalma.bsky.social