Raj Rajnarayanan
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rajlabn.bsky.social
Raj Rajnarayanan
@rajlabn.bsky.social
5.2K followers 200 following 330 posts
@Rajlabn in Twitter | My posts are my own
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rajlabn.bsky.social
Note: My initial dashboard missed a few sequences with missing nucleotides. Thanks to @josetteschoenma.bsky.social and @siamosolocani.bsky.social for nucleotide queries which pick up all BA.3.2* as of now.
November 9, 2025 at 6:43 PM
rajlabn.bsky.social
Pango issue, spotting & designation history:
github.com/cov-lineages...
November 9, 2025 at 6:42 PM
rajlabn.bsky.social
Excellent thread on BA.3 from @ryanhisner.bsky.social bsky.app/profile/ryan...
ryanhisner.bsky.social Ryan Hisner @ryanhisner.bsky.social · Mar 12
Do you remember BA.3—the weakling cousin of BA.1 & BA.2 that seemed to take the worst from each & had weaker ACE2 binding than even the ancestral Wuhan Virus?

After three years, BA.3 is back.

And it is transmitting.

Who saw this coming?
1/13
November 9, 2025 at 6:41 PM
rajlabn.bsky.social
BA.3.2 exhibits robust antibody evasion + low ACE2-binding capability (Guo et al, 2025; thelancet.com/journals/lan...
November 9, 2025 at 6:40 PM
rajlabn.bsky.social
Status of #COVID19 in #NewYork (#Bellwether State)

XFG.2, XFG.14.1, XFG.3.4.1, XFG.3 and XFG.4.2 are the top circulating #SARSCoV2 lineages in NY

#COVID19 hospitalizations - trending down| #WasteWater #SARSCoV2 -no recent update |
@HealthNYGov

2/n
November 8, 2025 at 7:09 AM
rajlabn.bsky.social
Thanks to all the countries that are supporting #SARSCoV2 testing & rapidly submitting sequences to @GISAID

Top submitters (> 100 Seqs w/ collection dates in the last 30 days): #UnitedKingdom #Canada #USA #France #Spain #Germany #Netherlands #Australia #Slovenia

3/n
November 5, 2025 at 4:08 AM
rajlabn.bsky.social
This analysis includes #SARSCoV2 sequences submitted to
@GISAID with sample collection dates on or after 10/04/2025 (3,862 sequences)

Note: 171,095 SARSCoV2 seqs w/ collection dates on or after 01/01/2025 are available in GISAID/NCBI

2/n
November 5, 2025 at 4:07 AM
rajlabn.bsky.social
Thanks to all the countries that are supporting #SARSCoV2 testing & rapidly submitting sequences to @GISAID

Top submitters (> 100 Seqs w/ collection dates in the last 30 days): #UnitedKingdom #USA #France #Canada #Spain #Netherlands #Australia #Germany #Italy

3/n
October 27, 2025 at 5:27 AM
rajlabn.bsky.social
This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 09/25/2025 (4,684 sequences)

Note: 164,341 SARSCoV2 seqs w/ collection dates on or after 01/01/2025 are available in GISAID/NCBI

2/n
October 27, 2025 at 5:26 AM
rajlabn.bsky.social
These are sequences with sample collection dates in the last 30 days - I can check if this is missing some seqs
October 17, 2025 at 4:01 PM
rajlabn.bsky.social
Following BA.3.2.2* in #WesternAustralia closely

4/n
October 17, 2025 at 5:11 AM
rajlabn.bsky.social
Thanks to all the countries that are supporting #SARSCoV2 testing & rapidly submitting sequences to @GISAID

Top submitters (> 100 Seqs w/ collection dates in the last 30 days): #Canada #USA #UnitedKingdom #Spain #France #Australia #Netherlands #Italy #Germany

3/n
October 17, 2025 at 5:11 AM
rajlabn.bsky.social
This analysis includes #SARSCoV2 sequences submitted to
@GISAID with sample collection dates on or after 09/16/2025 (5,714 sequences)

Note: 157,144 SARSCoV2 seqs w/ collection dates on or after 01/01/2025 are available in GISAID/NCBI

2/n
October 17, 2025 at 5:10 AM
rajlabn.bsky.social
This analysis includes #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 08/29/2025 (4,212 sequences)

Note: 146,261 seqs w/ collection dates on or after 01/01/2025 are available in GISAID/NCBI

2/n
October 6, 2025 at 6:30 AM
rajlabn.bsky.social
XFG* mutations under watch

Spike K529T is worth watching (its one of the signature mutations of XFG.14 lineage)
September 15, 2025 at 4:11 AM
rajlabn.bsky.social
Status of #COVID19 in #California

XFG.3, XFG, XFG.2 and PQ.2 are the top circulating #SARSCoV2 lineages in CA |[🚨Low sequence count]

#COVID19 hospitalizations -low | #WasteWater #SARSCoV2 - Very High | @capublichealth.bsky.social
September 15, 2025 at 4:10 AM
rajlabn.bsky.social
Status of #COVID19 in #NewYork (#Bellwether State)

XFG and XFG.3 are the top circulating #SARSCoV2 lineages in NY [🚨low sequence count]

#COVID19 hospitalizations - trending up| #WasteWater #SARSCoV2 -low | @HealthNYGov

2/n
September 15, 2025 at 4:07 AM
rajlabn.bsky.social
XFG.3* is the top circulating variant group in the world!

Top XFG sub-lineages in circulation (>=1%)

XFG.3, XFG, XFG.5, XFG.2, XFG.3.4.1, XFG.4.1,
XFG.9, XFG.8, XFG.3.1, XFG.3.4, XFG.6, XFG.3.4.3,
XFG.14.1, XFG.3.4.2, XFG.22, XFG.10, XFG.4, XFG.3.1.2,
XFG.21

102 XFG sub-lineages:

3/n
September 14, 2025 at 7:21 AM
rajlabn.bsky.social
Thanks to all the countries that are supporting #SARSCoV2 testing & rapidly submitting sequences to @GISAID

Top submitters #USA #Spain #UK #Canada #Australia #NewZealand #France #Brazil #Italy #SouthKorea #Netherlands #PuertoRico #Japan #Denmark #Ukraine #Singapore #China
2/n
September 14, 2025 at 7:20 AM