RadfordLab
@radford-lab.bsky.social
Radford Brockwell and Calabrese labs post here
See our latest paper on BAM action. Great work to the team and super collaborations with @naranson.bsky.social @antoncalabrese.bsky.social and @Jean Francois collet. Have a read rdcu.be/eJjDp
Molecular insights into how the motions of the β-barrel and POTRA domains of BamA are coupled for efficient function
Nature Communications - BamA is the catalytic core of the BAM complex, which inserts proteins into bacterial outer membranes. Here, the authors show that hinge flexibility between BamA’s...
rdcu.be
October 4, 2025 at 9:32 AM
See our latest paper on BAM action. Great work to the team and super collaborations with @naranson.bsky.social @antoncalabrese.bsky.social and @Jean Francois collet. Have a read rdcu.be/eJjDp
Delighted to see our new DMS of amyloid formation and predication of amyloid stability vs sequence changes out at PNAS. Brilliant work Conor! doi.org/10.1073/pnas...
Employing deep mutational scanning in the Escherichia coli periplasm to decode the thermodynamic landscape for amyloid formation | PNAS
Deep mutational scanning (DMS) assays provide a powerful method to generate large-scale
datasets essential for advancing AI-driven predictions in b...
doi.org
September 17, 2025 at 9:29 PM
Delighted to see our new DMS of amyloid formation and predication of amyloid stability vs sequence changes out at PNAS. Brilliant work Conor! doi.org/10.1073/pnas...
Our review on CPEB and memory published today- thanks to all authors. Enjoy the read
September 8, 2025 at 9:36 AM
Our review on CPEB and memory published today- thanks to all authors. Enjoy the read
Delighted to see Jon Machin's lovely OMP folding and assembly work on the front cover of JMB (doi: 10.1016/j.jmb.2025.169346) and in this Faraday Discussion article (doi: 10.1039/d4fd00180). Congratulations on your great work Jonathan!
August 30, 2025 at 12:15 PM
Delighted to see Jon Machin's lovely OMP folding and assembly work on the front cover of JMB (doi: 10.1016/j.jmb.2025.169346) and in this Faraday Discussion article (doi: 10.1039/d4fd00180). Congratulations on your great work Jonathan!
Interested in amyloid polymorphs? Our latest paper with PhD student Jack Connor is just out. Have a read and do try out his analysis on your favourite amyloid structures! doi.org/10.1016/j.st...
July 29, 2025 at 12:07 PM
Interested in amyloid polymorphs? Our latest paper with PhD student Jack Connor is just out. Have a read and do try out his analysis on your favourite amyloid structures! doi.org/10.1016/j.st...
Delighted to share our latest paper on OMPs and the effects of their interactions on OMP catalysis in the bacterial outer membrane. The latest super work from Jonathan Machin. See doi.org/10.1016/j.jm...
July 22, 2025 at 9:03 PM
Delighted to share our latest paper on OMPs and the effects of their interactions on OMP catalysis in the bacterial outer membrane. The latest super work from Jonathan Machin. See doi.org/10.1016/j.jm...
Great day celebrating Katy Dewison’s PhD. Good luck in all you do in the future Katy in your postdoc at Aarhus. We will miss you’
July 22, 2025 at 7:42 AM
Great day celebrating Katy Dewison’s PhD. Good luck in all you do in the future Katy in your postdoc at Aarhus. We will miss you’
Super FASEB meeting on protein misfolding and amyloid fibre polymorphs in Phoenix Arizona. Hot science and a hot place (45C)! Katy and Jack did a great job presenting their data in talks and posters.
July 4, 2025 at 2:31 AM
Super FASEB meeting on protein misfolding and amyloid fibre polymorphs in Phoenix Arizona. Hot science and a hot place (45C)! Katy and Jack did a great job presenting their data in talks and posters.
So proud our lab was awarded Gold LEAF status for sustainability. Thanks to Nasir Khan, Tabitha Howe and @antoncalabrese.bsky.social for making it happen for us all! Keep up the good work!
June 13, 2025 at 6:18 PM
So proud our lab was awarded Gold LEAF status for sustainability. Thanks to Nasir Khan, Tabitha Howe and @antoncalabrese.bsky.social for making it happen for us all! Keep up the good work!
Two prizes in one day! So proud of Maddie Gilbert and Katy Dewison who each was awarded a prize for their PhD thesis work in the Faculty of Biological Sciences on Alzheimer’s and Parkinson’s disease respectively.
June 7, 2025 at 9:01 AM
Two prizes in one day! So proud of Maddie Gilbert and Katy Dewison who each was awarded a prize for their PhD thesis work in the Faculty of Biological Sciences on Alzheimer’s and Parkinson’s disease respectively.
Reposted by RadfordLab
Beautiful and inspiring talk by Sheena Radford of the @radford-lab.bsky.social at the Astbury Centre for Structural Molecular Biology (@astbury-bsl.bsky.social) from the University of Leeds (@universityofleeds.bsky.social) at our annual Bijvoet Symposium!
May 12, 2025 at 10:11 AM
Beautiful and inspiring talk by Sheena Radford of the @radford-lab.bsky.social at the Astbury Centre for Structural Molecular Biology (@astbury-bsl.bsky.social) from the University of Leeds (@universityofleeds.bsky.social) at our annual Bijvoet Symposium!
Honoured to sign the book to become an international member of the National Academy of Sciences. Proud to receive this in recognition of all the work of many group members and collaborators over the years. Thank you all.
April 26, 2025 at 3:13 PM
Honoured to sign the book to become an international member of the National Academy of Sciences. Proud to receive this in recognition of all the work of many group members and collaborators over the years. Thank you all.
Our commentary on flow and amyloid formation published today www.pnas.org/doi/10.1073/pnas.2504573122
April 16, 2025 at 6:13 PM
Our commentary on flow and amyloid formation published today www.pnas.org/doi/10.1073/pnas.2504573122
At last our paper is out at JACS and we made the front cover! Thanks to Phospho animation for the image. See doi.org/10.1021/jacs....
April 10, 2025 at 2:13 PM
At last our paper is out at JACS and we made the front cover! Thanks to Phospho animation for the image. See doi.org/10.1021/jacs....
Had a wonderful time at ADAM10 in Gothenburg with old and new friends! Thank you for a great 3 days of amyloid science.
March 23, 2025 at 10:14 AM
Had a wonderful time at ADAM10 in Gothenburg with old and new friends! Thank you for a great 3 days of amyloid science.
Reposted by RadfordLab
Looking forward #ADAM10 kick-off 🇸🇪 3 days of all things amyloid and great opportunity to meet old friends and making new ones! Thanks @professorpernilla.bsky.social and Elin Esbjorner et al for such a great program. Reach out if you are around
www.chalmers.se/en/conferenc...
www.chalmers.se/en/conferenc...
March 19, 2025 at 10:07 AM
Looking forward #ADAM10 kick-off 🇸🇪 3 days of all things amyloid and great opportunity to meet old friends and making new ones! Thanks @professorpernilla.bsky.social and Elin Esbjorner et al for such a great program. Reach out if you are around
www.chalmers.se/en/conferenc...
www.chalmers.se/en/conferenc...
Reposted by RadfordLab
Just some of the amazing scientists @universityofleeds.bsky.social in FBS, #international women’s day
March 8, 2025 at 7:44 AM
Just some of the amazing scientists @universityofleeds.bsky.social in FBS, #international women’s day
Proud to be part of this great article with @ldaubrey.bsky.social . Of interest to all working on amyloid polymorphs see doi.org/10.1016/j.jmb.2025.169008
March 2, 2025 at 12:21 PM
Proud to be part of this great article with @ldaubrey.bsky.social . Of interest to all working on amyloid polymorphs see doi.org/10.1016/j.jmb.2025.169008
Delighted our latest paper on amyloid polymorphs is published in JACS- doi 10.1021/jacs.4c16743. Well done all- very proud!
February 23, 2025 at 2:04 PM
Delighted our latest paper on amyloid polymorphs is published in JACS- doi 10.1021/jacs.4c16743. Well done all- very proud!
Reposted by RadfordLab
February 16, 2025 at 10:33 PM
Super visit to UTSWCentre for Alzheimer and Neurodegeneration yesterday and to see Nikos Louros- a great host in a frozen and cold Dallas!
February 14, 2025 at 1:40 PM
Super visit to UTSWCentre for Alzheimer and Neurodegeneration yesterday and to see Nikos Louros- a great host in a frozen and cold Dallas!
Are you interested in proteins as exciting, dynamic interacting species. Come and join our meeting on March 28th 2025. Places are limited so register ASAP (£25 only!) at sheena-radford-lab.uk/fida.php.
New news- thanks to British Biophys Soc travel bursaries will be available for ECR registrants.
New news- thanks to British Biophys Soc travel bursaries will be available for ECR registrants.
January 28, 2025 at 10:52 PM
Are you interested in proteins as exciting, dynamic interacting species. Come and join our meeting on March 28th 2025. Places are limited so register ASAP (£25 only!) at sheena-radford-lab.uk/fida.php.
New news- thanks to British Biophys Soc travel bursaries will be available for ECR registrants.
New news- thanks to British Biophys Soc travel bursaries will be available for ECR registrants.
Do come snd join our excellent meeting. All welcome for a great day of science of proteins in action. And all for £25!! We would love to see you and our conference venue is great too!
Are you interested in proteins as exciting, dynamic interacting species. Come and join us- March 28th 2025.
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
January 20, 2025 at 12:14 PM
Do come snd join our excellent meeting. All welcome for a great day of science of proteins in action. And all for £25!! We would love to see you and our conference venue is great too!
Reposted by RadfordLab
Are you interested in proteins as exciting, dynamic interacting species. Come and join us- March 28th 2025.
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
January 11, 2025 at 4:25 PM
Are you interested in proteins as exciting, dynamic interacting species. Come and join us- March 28th 2025.
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
Places are limited so please register ASAP at sheena-radford-lab.uk/fida.php. (£25.00 registration only, including excellent catering).
Reposted by RadfordLab
Brilliant talk (introduced by our VC Lisa Roberts) on the formation of a temporal series of amyloid aggregates in driving human diseases by Sheena Radford at our distinguished lecturer series. @lsiexeter.bsky.social a
LSI / Biosciences @ Exeter.
LSI / Biosciences @ Exeter.
January 15, 2025 at 4:36 PM
Brilliant talk (introduced by our VC Lisa Roberts) on the formation of a temporal series of amyloid aggregates in driving human diseases by Sheena Radford at our distinguished lecturer series. @lsiexeter.bsky.social a
LSI / Biosciences @ Exeter.
LSI / Biosciences @ Exeter.