Rabi Hanna - Cell & Gene therapy Doc
@rabihannamd.bsky.social
Chief of Pediatric hem-Onc & BMT @ClevelandClinic #CleClinicCancer @cleclinickids #CleClinicPedsCancer #ChildhoodCancer #pedcsm #bmtsm. Posts are my own opinion.
Grateful to our amazing @CleClinic_PHO team for shining so brightly at #LightTheNight 🌟 Your passion and advocacy bring hope to leukemia & lymphoma patients and families every day. Together, we’re lighting the path toward a cure. ❤️🕯️ #LLS #TeamClevelandClinic @bloodcancerunited.bsky.social
October 5, 2025 at 11:02 PM
Grateful to our amazing @CleClinic_PHO team for shining so brightly at #LightTheNight 🌟 Your passion and advocacy bring hope to leukemia & lymphoma patients and families every day. Together, we’re lighting the path toward a cure. ❤️🕯️ #LLS #TeamClevelandClinic @bloodcancerunited.bsky.social
You want to feel good and 🤩👏… come to @velosano . Nothing feels as good as being with previous #ChildhoodCancer patients who are now #Survivors and #riding for the #Cure
September 6, 2025 at 5:49 PM
You want to feel good and 🤩👏… come to @velosano . Nothing feels as good as being with previous #ChildhoodCancer patients who are now #Survivors and #riding for the #Cure
Here we go ; safe ride to all #Riders @bikeVeloSano 25 miles. 🙏thank you so much for all you do to raise $ for #CancerResearch at @ClevelandClinic 💯 for the #Cure . Cancer impact goes beyond one patient , one family … it affects the community and together 💪 can make an impact
September 6, 2025 at 5:48 PM
Here we go ; safe ride to all #Riders @bikeVeloSano 25 miles. 🙏thank you so much for all you do to raise $ for #CancerResearch at @ClevelandClinic 💯 for the #Cure . Cancer impact goes beyond one patient , one family … it affects the community and together 💪 can make an impact
Mentorship is a powerful way to give back in #PedsHemOnc. I am so honored to be among #mentors at the American society of pediatric hematology - oncology speedy mentorship supporting the next generation boosts career satisfaction, fosters personal growth & strengthens our field for the future.
May 9, 2025 at 4:43 PM
Mentorship is a powerful way to give back in #PedsHemOnc. I am so honored to be among #mentors at the American society of pediatric hematology - oncology speedy mentorship supporting the next generation boosts career satisfaction, fosters personal growth & strengthens our field for the future.
Dr. Caitlyn Duffy from @stjude.bsky.social presented great talk at poem_group about Implementation science in leukemia
1- discussed the 17 year odessy - translation of discovery to delivery
2- EPIS implementation framework
1- discussed the 17 year odessy - translation of discovery to delivery
2- EPIS implementation framework
May 1, 2025 at 2:42 PM
Dr. Caitlyn Duffy from @stjude.bsky.social presented great talk at poem_group about Implementation science in leukemia
1- discussed the 17 year odessy - translation of discovery to delivery
2- EPIS implementation framework
1- discussed the 17 year odessy - translation of discovery to delivery
2- EPIS implementation framework
So grateful to be invited to #POEM 4th Scientific Conference! Connecting with ped oncologists to improve care & access for kids with cancer has been truly inspiring. 👏🎉 Dr. rawad rihani and Dr. Gevory Tamamyan for fantastic reception to start #POEM2025 #PediatricOncology #CancerCare
May 1, 2025 at 1:32 AM
So grateful to be invited to #POEM 4th Scientific Conference! Connecting with ped oncologists to improve care & access for kids with cancer has been truly inspiring. 👏🎉 Dr. rawad rihani and Dr. Gevory Tamamyan for fantastic reception to start #POEM2025 #PediatricOncology #CancerCare
Thank you 👏 Dr. Jim Fernandez for organising great conference #PrimaryImmunodeficiency at @ClevelandClinic and great talk about #IVIG . It is amazing to see the use increase significantly.
Did you know it takes 8-9 months to make IVIG and it approximately collected from 15,000 donors
Did you know it takes 8-9 months to make IVIG and it approximately collected from 15,000 donors
April 5, 2025 at 12:35 PM
Thank you 👏 Dr. Jim Fernandez for organising great conference #PrimaryImmunodeficiency at @ClevelandClinic and great talk about #IVIG . It is amazing to see the use increase significantly.
Did you know it takes 8-9 months to make IVIG and it approximately collected from 15,000 donors
Did you know it takes 8-9 months to make IVIG and it approximately collected from 15,000 donors
Great advice by Troy Torgerson about what to do when you have VUS “variable unknown significance “ at @clevelandclinic.bsky.social #PrimaryImmuneDeficiency symposium
April 4, 2025 at 7:33 PM
Great advice by Troy Torgerson about what to do when you have VUS “variable unknown significance “ at @clevelandclinic.bsky.social #PrimaryImmuneDeficiency symposium
The fight against # ChildhhodCancer is not just medical challenge - it is calling - beyond medication to wholistic care
So proud of our music therapist 🎉👏 Emily Ervin @CleClinicKids for supporting kids - see picture below 👇 with one of our kids cutting her hair
So proud of our music therapist 🎉👏 Emily Ervin @CleClinicKids for supporting kids - see picture below 👇 with one of our kids cutting her hair
March 30, 2025 at 5:50 PM
The fight against # ChildhhodCancer is not just medical challenge - it is calling - beyond medication to wholistic care
So proud of our music therapist 🎉👏 Emily Ervin @CleClinicKids for supporting kids - see picture below 👇 with one of our kids cutting her hair
So proud of our music therapist 🎉👏 Emily Ervin @CleClinicKids for supporting kids - see picture below 👇 with one of our kids cutting her hair
So proud and inspired by our team : Preston , Katie and Stacey participating in @clevelandclinic.bsky.social #StBaldrick shave for the cure event
We are doing what we do to support kids & their families and organisations like St Baldrick so we can do research to find more cure and better therapies
We are doing what we do to support kids & their families and organisations like St Baldrick so we can do research to find more cure and better therapies
March 30, 2025 at 4:53 PM
So proud and inspired by our team : Preston , Katie and Stacey participating in @clevelandclinic.bsky.social #StBaldrick shave for the cure event
We are doing what we do to support kids & their families and organisations like St Baldrick so we can do research to find more cure and better therapies
We are doing what we do to support kids & their families and organisations like St Baldrick so we can do research to find more cure and better therapies
So excited to welcome our #Pediatric residents at @clevelandclinic.bsky.social
To join all our care givers in our mission “Caring for life, researching for health, educating those who serve”
To join all our care givers in our mission “Caring for life, researching for health, educating those who serve”
March 21, 2025 at 4:59 PM
So excited to welcome our #Pediatric residents at @clevelandclinic.bsky.social
To join all our care givers in our mission “Caring for life, researching for health, educating those who serve”
To join all our care givers in our mission “Caring for life, researching for health, educating those who serve”
Great job 👏 👏 by Dr. Mark Walters @uscfb.bsky.social to present RUBY study sponsored @editasmed -Gene therapy for #SCD
- sustained normal hemoglobin and hgb F above >40%
- F cells >>99.3%
- pain free in 27/28 patients
- improved QOL
- sustained normal hemoglobin and hgb F above >40%
- F cells >>99.3%
- pain free in 27/28 patients
- improved QOL
February 13, 2025 at 2:05 AM
Great job 👏 👏 by Dr. Mark Walters @uscfb.bsky.social to present RUBY study sponsored @editasmed -Gene therapy for #SCD
- sustained normal hemoglobin and hgb F above >40%
- F cells >>99.3%
- pain free in 27/28 patients
- improved QOL
- sustained normal hemoglobin and hgb F above >40%
- F cells >>99.3%
- pain free in 27/28 patients
- improved QOL
Thrilled to be again in Kuwait and excited to hear about #PedBMT program growth presented by Dr Sondus Alsharidah at the 4th Kuwait 🇰🇼 Ped BMT & Gene therapy conference. 👏🎉 work. BMT is not quick surgery and rather a long journey and best care is local where patients families can be supported
January 21, 2025 at 6:23 AM
Thrilled to be again in Kuwait and excited to hear about #PedBMT program growth presented by Dr Sondus Alsharidah at the 4th Kuwait 🇰🇼 Ped BMT & Gene therapy conference. 👏🎉 work. BMT is not quick surgery and rather a long journey and best care is local where patients families can be supported
What a fantastic late breaking abstract fantastic by Françoise Bernaudin @ASH_hematology #ASH24: long term outcomes in DREPAGREFFE study evaluating all-HSCT in # SCD with abnormal cerebral velocity.
- alloSCT provided better primary prevention of stroke, ⬆️social QoL, working memory
- alloSCT provided better primary prevention of stroke, ⬆️social QoL, working memory
December 10, 2024 at 4:55 PM
What a fantastic late breaking abstract fantastic by Françoise Bernaudin @ASH_hematology #ASH24: long term outcomes in DREPAGREFFE study evaluating all-HSCT in # SCD with abnormal cerebral velocity.
- alloSCT provided better primary prevention of stroke, ⬆️social QoL, working memory
- alloSCT provided better primary prevention of stroke, ⬆️social QoL, working memory
Congratulations 👏🎉 Dr John Tisdale for receiving well deserved recognitions and The Ernest Beutler Lecture award #ASH24 @ash-hematology.bsky.social
His work on #GeneTherapy and #BMT IN #SCD opened the path for many treatments and saved so many lives .
His work on #GeneTherapy and #BMT IN #SCD opened the path for many treatments and saved so many lives .
December 10, 2024 at 12:13 AM
Congratulations 👏🎉 Dr John Tisdale for receiving well deserved recognitions and The Ernest Beutler Lecture award #ASH24 @ash-hematology.bsky.social
His work on #GeneTherapy and #BMT IN #SCD opened the path for many treatments and saved so many lives .
His work on #GeneTherapy and #BMT IN #SCD opened the path for many treatments and saved so many lives .
congratulations 👏🎉 to Dr. Sean Morrison who received this year @ash-hematology.bsky.social #ASH24 E. Donnall Thomas lecture award for his work on hematopoietic stem cell biology. Interesting work on importance of BM niche #BMT interesting work on impact of B blockers on engraftment
December 9, 2024 at 5:29 PM
congratulations 👏🎉 to Dr. Sean Morrison who received this year @ash-hematology.bsky.social #ASH24 E. Donnall Thomas lecture award for his work on hematopoietic stem cell biology. Interesting work on importance of BM niche #BMT interesting work on impact of B blockers on engraftment
Sen Zhan , PhD presented data at #ASH24 plenary session- PF4 impact on murine and human HSC aging .
This could provide targeted therapies for HSC rejuvenation and potential strategies improve the course of age-related immune dysfunction and hematopoietic diseases
#aging #HSC
This could provide targeted therapies for HSC rejuvenation and potential strategies improve the course of age-related immune dysfunction and hematopoietic diseases
#aging #HSC
December 8, 2024 at 11:01 PM
Two more points made by Dr. Rau #ASH24
1- despite that Blina has not been tested in Adolescents /HR-ALL but we could probably extrapolate that Blina could also decrease Relapse risk
2- increased risk of grade 3+ infections beyond cycles of Blina
#ChildhoodCancer
cure more Pts , and to cure better
1- despite that Blina has not been tested in Adolescents /HR-ALL but we could probably extrapolate that Blina could also decrease Relapse risk
2- increased risk of grade 3+ infections beyond cycles of Blina
#ChildhoodCancer
cure more Pts , and to cure better
December 8, 2024 at 10:49 PM
Two more points made by Dr. Rau #ASH24
1- despite that Blina has not been tested in Adolescents /HR-ALL but we could probably extrapolate that Blina could also decrease Relapse risk
2- increased risk of grade 3+ infections beyond cycles of Blina
#ChildhoodCancer
cure more Pts , and to cure better
1- despite that Blina has not been tested in Adolescents /HR-ALL but we could probably extrapolate that Blina could also decrease Relapse risk
2- increased risk of grade 3+ infections beyond cycles of Blina
#ChildhoodCancer
cure more Pts , and to cure better
Dr. Rachel Rau presented Children Oncology Group study ALL1731 study at plenary session #ASH24 👏👏
1- Blina decreased BM relapse significantly across all risk factors including ; hypodyploid , +MRD , Latino ethnicity, etc
2- no change in CNS relapse
#ChildhoodCancer #Leukemia
1- Blina decreased BM relapse significantly across all risk factors including ; hypodyploid , +MRD , Latino ethnicity, etc
2- no change in CNS relapse
#ChildhoodCancer #Leukemia
December 8, 2024 at 10:47 PM
Dr. Rachel Rau presented Children Oncology Group study ALL1731 study at plenary session #ASH24 👏👏
1- Blina decreased BM relapse significantly across all risk factors including ; hypodyploid , +MRD , Latino ethnicity, etc
2- no change in CNS relapse
#ChildhoodCancer #Leukemia
1- Blina decreased BM relapse significantly across all risk factors including ; hypodyploid , +MRD , Latino ethnicity, etc
2- no change in CNS relapse
#ChildhoodCancer #Leukemia
Congratulations 🎉and very well deserved to Dr. Elaine Gluckman for receiving #ASH24 WALLACE H. COULTER AWARD - life time achievement in Hematology . She pioneered cord blood transplantation and made great advances in care of non-malignant blood disorder patients
December 8, 2024 at 10:10 PM
Congratulations 🎉and very well deserved to Dr. Elaine Gluckman for receiving #ASH24 WALLACE H. COULTER AWARD - life time achievement in Hematology . She pioneered cord blood transplantation and made great advances in care of non-malignant blood disorder patients
Update fromBbluebird bio HGB-206 group C and HG -210 study regarding Lovo-cel for #SCD at #ASH24.
- Data about 58 patients
- 86.8% achieved complete resolution of all VOE
- 94.7% had complete reduction of severe VOE
- Model to predict likelihood of VOE-CR and sVOE-CR at 6 months
- Data about 58 patients
- 86.8% achieved complete resolution of all VOE
- 94.7% had complete reduction of severe VOE
- Model to predict likelihood of VOE-CR and sVOE-CR at 6 months
December 8, 2024 at 6:51 PM
Impressive results about Exa-Cel in TDT from @vertexpharma.bsky.social at #ASH24
- 54 patients
- 98% (53/54) had achieved Transfusion free x12 months
- the remaining patient is free of RBC Tx for at least 8 months
Similar results about safety and efficacy in #SCD
- 54 patients
- 98% (53/54) had achieved Transfusion free x12 months
- the remaining patient is free of RBC Tx for at least 8 months
Similar results about safety and efficacy in #SCD
December 8, 2024 at 6:45 PM
Impressive results about Exa-Cel in TDT from @vertexpharma.bsky.social at #ASH24
- 54 patients
- 98% (53/54) had achieved Transfusion free x12 months
- the remaining patient is free of RBC Tx for at least 8 months
Similar results about safety and efficacy in #SCD
- 54 patients
- 98% (53/54) had achieved Transfusion free x12 months
- the remaining patient is free of RBC Tx for at least 8 months
Similar results about safety and efficacy in #SCD
BEACON study initial data @beamforall.bsky.social IN #AS24
- BASE editing in Hgb1/2 for #SCD :7 patients
- less collection cycles
- faster engraftment in ANC (17 days) and PLT (19 days)
- one death
- high level of hgb F (>60%) with improvement in total hemoglobin and less hemolysis
- BASE editing in Hgb1/2 for #SCD :7 patients
- less collection cycles
- faster engraftment in ANC (17 days) and PLT (19 days)
- one death
- high level of hgb F (>60%) with improvement in total hemoglobin and less hemolysis
December 8, 2024 at 6:44 PM
BEACON study initial data @beamforall.bsky.social IN #AS24
- BASE editing in Hgb1/2 for #SCD :7 patients
- less collection cycles
- faster engraftment in ANC (17 days) and PLT (19 days)
- one death
- high level of hgb F (>60%) with improvement in total hemoglobin and less hemolysis
- BASE editing in Hgb1/2 for #SCD :7 patients
- less collection cycles
- faster engraftment in ANC (17 days) and PLT (19 days)
- one death
- high level of hgb F (>60%) with improvement in total hemoglobin and less hemolysis