Hai Qi
@qi-tsinghua.bsky.social
Immunologist, Professor, working Tsinghua Univ, Institute for Immunology; on X/twitter: @Qi_Tisnghua
Web: ldi2009.tsinghua.edu.cn
Web: ldi2009.tsinghua.edu.cn
(1/4) Our newest discovery on B-cell memory, just published @cp-immunity.bsky.social : the development of memory B cells from germinal centers requires IL-9 derived from T cells, which instructs MBC development through the action of transcription factor ZBTB18. www.cell.com/immunity/ful...
An interleukin-9-ZBTB18 axis promotes germinal center development of memory B cells
Memory B cells (MBCs) emerging from germinal centers (GCs) are crucial for antibody-based
vaccines. Luo, Hou, et al. find that T cell-derived interleukin-9 promotes expression
of the transcriptional r...
www.cell.com
March 18, 2025 at 4:10 PM
(1/4) Our newest discovery on B-cell memory, just published @cp-immunity.bsky.social : the development of memory B cells from germinal centers requires IL-9 derived from T cells, which instructs MBC development through the action of transcription factor ZBTB18. www.cell.com/immunity/ful...
Day 1, good start with Mark Davis, the symposium "Deconstruction and reconstruction of lymphocytes for precision medicine" in Shenzhen, China
March 3, 2025 at 3:47 AM
Day 1, good start with Mark Davis, the symposium "Deconstruction and reconstruction of lymphocytes for precision medicine" in Shenzhen, China
Excited to share our new study nature.com/articles/s41... in which we functionally define a new memory CD8 subset, a novel CD8 T cell-driven complement activation pathway, and a new CD8 T cell-mediated pathogenic mechanism of allergy.
GZMK-expressing CD8+ T cells promote recurrent airway inflammatory diseases - Nature
Comparing T cells in nasal polyps from repeated surgeries shows that effector memory-like persistent clones colonize the mucosal tissue during disease recurrence and promote inflammation by producing ...
nature.com
January 15, 2025 at 4:19 PM
Excited to share our new study nature.com/articles/s41... in which we functionally define a new memory CD8 subset, a novel CD8 T cell-driven complement activation pathway, and a new CD8 T cell-mediated pathogenic mechanism of allergy.