Amanda Randles 🧪⚛️ 👩‍🔬
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profamandarandles.bsky.social
Amanda Randles 🧪⚛️ 👩‍🔬
@profamandarandles.bsky.social
Director of the Duke University Center for Computational and Digital Health Innovation. Alfred Winborne Mordecai and Victoria Stover Mordecai Associate Professor of Biomedical Engineering. Research in HPC and digital twins for health.
Excited to share a new Communications of the ACM article highlighting our work on vascular digital twins—using millions of simulated heartbeats and wearable data to help predict heart issues long before symptoms appear. 🔗https://duke.is/cacm25
November 13, 2025 at 9:30 PM
Join us tomorrow for Dr. Michael Rubinstein’s virtual talk, “The Loops of Life.” Explore how molecular size, topology, and interactions shape polymers.

Register: duke.qualtrics.com/jfe/form/SV_...

@dukeengineering.bsky.social @dukeubme.bsky.social
November 6, 2025 at 3:16 AM
At the Center for Computational and Digital Health Innovation, we’re advancing technology with purpose.
Proud to spotlight Cameron Kim, who’s shaping the future of ethical digital health innovation and preparing the next generation of leaders.
comphealth.duke.edu/featured-res...
October 15, 2025 at 4:02 PM
So proud of the Randles Lab team for their fantastic presentations at #BMES2025—from cardiovascular digital twins and wearable-driven modeling to cellular biomechanics. Exciting to see their work pushing the boundaries of computational and digital health. #DukeBME #ProudPI
October 15, 2025 at 1:52 PM
🧪I didn’t get to post about this earlier, but I recently had the honor of giving the opening keynote at IWOMP 2025. I had a great time talking with the MPI and OpenMP community about opportunities to bring HPC advances to health and scale vascular digital twins. #HPC #OpenMP #MPI #DigitalTwins
October 13, 2025 at 5:24 PM
Great to join the 2nd Annual Duke Summit on AI for Health Innovation, hosted by @dukeaihealth.bsky.social, the Center for Computational and Digital Health Innovation, and DCRI.

Exciting discussions on AI, digital twins, and the future of healthcare. #AIforHealth #DigitalHealth #HPC #Innovation
October 13, 2025 at 4:50 PM
It’s #BMES2025! The Randles Lab is sharing new work on digital twins for heart failure, HRV-based model reduction, cellular heterogeneity, and APR modeling of RBC–cancer interactions. Stop by the Duke booth to learn about our Center for Computational and Digital Health Innovation! #DigitalHealth
October 8, 2025 at 4:01 AM
Join us Wed, Oct 2 @ 3 PM ET for the Center for Computational and Digital Health Innovation + Duke Quantitative Biodesign Virtual Seminar! Fabian Theis (Helmholtz Munich/TUM) will speak on “Decoding cellular systems.” All welcome. Register: duke.qualtrics.com/jfe/form/SV_...
October 2, 2025 at 3:06 AM
Full circle. From my first HLF as a student in 2013 ➡️ to giving a talk on stage as a laureate this year. Grateful for the journey and the community that made it possible. #HLF2025
September 18, 2025 at 9:52 PM
Yesterday our Center hosted the first Espresso Chat ☕ with Jeff Hammond! He shared his path from quantum chemistry to #HPC and reminded students to lean into strengths, keep learning, and stay ahead of the curve. Favorite moment: a Valentine that read “Jeff the Scientist.” #CareerJourney
September 12, 2025 at 8:35 PM
We’re excited to welcome Leah Howell to the Randles Lab as a new graduate student in Biomedical Engineering!

Looking forward to all the discoveries ahead—welcome to the team, Leah!

#RandlesLab #bme #dukebme #dukeuniversity
September 10, 2025 at 4:15 PM
🧪👩‍🔬Congrats to Wendy Wu on advancing to PhD Candidacy in Biomedical Engineering! Her work on computational models of cellular mechanics is pushing forward digital health innovation. Proud PI moment (yes, I was the one taking pics mid-exam). #WomenInSTEM #PhDCandidate
September 8, 2025 at 3:09 PM
Excited to be speaking at the @WichitaState BME Seminar this Friday (Sept 5)!

📢 Talk: Developing and Applying Vascular Digital Twins
🕑 2:00–3:15 PM CT

Exploring HPC + wearables for real-time cardiovascular health. #DigitalTwins #HPC #BME
September 5, 2025 at 2:48 AM
🧪 #CompHealth Corner: High-channel neural interfaces are here—but routing dense pad grids is a major hurdle. This new paper from #CCDHI member Jonathan Viventi introduces an efficient, automated algorithm to optimize trace paths and layer count in thin-film devices. #Neuroengineering #HCI
August 29, 2025 at 11:47 AM
Launching Fall 2025: Duke’s Computational & Digital Health Certificate 🎓 Training future leaders at the intersection of AI, modeling, wearables & ethics. Learn more: duke.is/certificate #DigitalHealth #AI @dukeengineering.bsky.social
August 28, 2025 at 1:49 PM
New in npj Digital Medicine: Our proof-of-concept digital twins predict pulmonary pressures noninvasively, offering a path to earlier detection & better care for right heart failure. duke.is/hf
August 27, 2025 at 7:34 PM
CompHealth Corner: What Are We Reading?
📘 Paper from Center researcher Jonathan Viventi in the Journal of Neural Engineering: a deepest-exit-first algorithm for routing dense pad grids in thin-film neural interfaces—solving a key bottleneck in scaling next-gen implants.
#Neurotech #AI 🧪
August 22, 2025 at 9:32 PM
Fun new wall art from LLNL :) still figuring out where to put it but it’s pretty cool. (And yes those are part of my #SC jacket collection below. We all have SC clothes in our offices right?) #hpc #scivis #artofhpc
August 21, 2025 at 6:27 PM
🧪 When doctors track heart disease, they need scans over time—but aligning them is tough, tedious, and subjective. We built an algorithm that automates alignment, saving time and effort.

Read more 👉 duke.is/align24

@dukeengineering.bsky.social #research #comphealth #CCDHI #cardiovascular
August 19, 2025 at 1:11 PM
CompHealthCorner: HPC powers today’s AI, science, and innovation—but U.S. leadership is at risk. This Science article urges a bold, whole-nation roadmap to secure the future of high-performance computing. A must-read for anyone in tech policy. #CompHealthCorner #HPC #AI #SciencePolicy
August 15, 2025 at 11:51 AM
Dr. John Hickey, our co-Associate Director of AI, is pioneering AI-empowered systems biology to advance spatial cell therapies. His award-winning work marries engineering, immunology & computation to shape the future of personalized medicine.
Read more: comphealth.duke.edu/featured-res...
August 14, 2025 at 7:26 PM
Added some new personal touches to the office to kick off the new year :) as part of my sabbatical this year, we took the kids to Australia (yes I questioned the long flight too :)) and I thought I would add some pics to my office. Do you have family artwork or custom mousepads in your office?
August 14, 2025 at 4:49 PM
How can AI in healthcare reduce bias instead of reinforcing it? This week’s #CompHealthCorner spotlights a new Nursing Outlook article by Ben Goldstein and colleagues on HUMAINE—a team‑developed curriculum to equip nurse scientists in AI, bias mitigation, and equity.
August 11, 2025 at 1:05 PM
🧪Oops—July’s #CompHealthCorner is a few days late (I was traveling)! Catch up on key papers in ML-driven MD, RAG in medicine, open-source ANS tools, and award-winning cancer simulations. Don’t miss these breakthroughs! 👉 comphealth.duke.edu/comphealth-c... #DigitalHealth #AI #Bioengineering
August 8, 2025 at 8:16 PM
🧪As the nursing shortage grows, robotics powered by physical AI may help extend care. This #CCDHI article shows how nurses can lead in designing ethical, human-centered robotic systems to support—not replace—care. A must-read for future-ready healthcare. #CompHealthCorner #AIinNursing
August 8, 2025 at 3:19 PM