#SingleCell preprints
@prepub-singlecell.bsky.social
feeds: biorxiv, medrxiv, arxiv.q-bio, arxiv.cs, arxiv.math, Research Square
regex: '(single(- )(cell|nuclei)|s[cn]RNA-seq)'
If you have suggestions, please get in contact with @willmacnair :)
regex: '(single(- )(cell|nuclei)|s[cn]RNA-seq)'
If you have suggestions, please get in contact with @willmacnair :)
Targeting STING-ATM axis overcomes radiotherapy-induced immune suppression and restores anti-tumor immunity in nasopharyngeal carcinoma #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.12.687945v1
https://www.biorxiv.org/content/10.1101/2025.11.12.687945v1
November 13, 2025 at 5:01 PM
Targeting STING-ATM axis overcomes radiotherapy-induced immune suppression and restores anti-tumor immunity in nasopharyngeal carcinoma #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.12.687945v1
https://www.biorxiv.org/content/10.1101/2025.11.12.687945v1
Epigenetic silencing of transposable elements by IRF2BP2 is a selective dependency of myeloid leukemia #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.12.688028v1
https://www.biorxiv.org/content/10.1101/2025.11.12.688028v1
November 13, 2025 at 5:01 PM
Epigenetic silencing of transposable elements by IRF2BP2 is a selective dependency of myeloid leukemia #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.12.688028v1
https://www.biorxiv.org/content/10.1101/2025.11.12.688028v1
Engagement of the T cell receptor against an oncolytic virus generates a population of hypereffector CAR T cells with potent antitumor activity #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7949545/latest
https://www.researchsquare.com/article/rs-7949545/latest
November 13, 2025 at 5:01 PM
Engagement of the T cell receptor against an oncolytic virus generates a population of hypereffector CAR T cells with potent antitumor activity #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7949545/latest
https://www.researchsquare.com/article/rs-7949545/latest
Embigin is involved in the regulation of early mouse kidney development #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7750633/latest
https://www.researchsquare.com/article/rs-7750633/latest
November 13, 2025 at 5:01 PM
Embigin is involved in the regulation of early mouse kidney development #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7750633/latest
https://www.researchsquare.com/article/rs-7750633/latest
Identified BIRC5 and HDAC1 as Novel Diagnostic Biomarkers Linked to Centrosome-Immune Crosstalk for Cutaneous Squamous Cell Carcinoma via Machine Learning-Based Multi-omics Analysis #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7496212/latest
https://www.researchsquare.com/article/rs-7496212/latest
November 13, 2025 at 5:01 PM
Identified BIRC5 and HDAC1 as Novel Diagnostic Biomarkers Linked to Centrosome-Immune Crosstalk for Cutaneous Squamous Cell Carcinoma via Machine Learning-Based Multi-omics Analysis #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7496212/latest
https://www.researchsquare.com/article/rs-7496212/latest
Single cell RNA sequencing reveals unexpected heterogeneity and identifies AP2XI-6 as an in vivo bradyzoite specific cell cycle regulator #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7973787/latest
https://www.researchsquare.com/article/rs-7973787/latest
November 13, 2025 at 5:01 PM
Single cell RNA sequencing reveals unexpected heterogeneity and identifies AP2XI-6 as an in vivo bradyzoite specific cell cycle regulator #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7973787/latest
https://www.researchsquare.com/article/rs-7973787/latest
SC-Framework: A robust and FAIR semi-interactive environment for single-cell resolution datasets #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.11.687874v1
https://www.biorxiv.org/content/10.1101/2025.11.11.687874v1
November 13, 2025 at 5:00 PM
SC-Framework: A robust and FAIR semi-interactive environment for single-cell resolution datasets #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.11.687874v1
https://www.biorxiv.org/content/10.1101/2025.11.11.687874v1
BarlowTrack: A Self-Supervised Framework for Zero-Shot Multi-Object Cell Tracking #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687595v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687595v1
November 13, 2025 at 8:00 AM
BarlowTrack: A Self-Supervised Framework for Zero-Shot Multi-Object Cell Tracking #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687595v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687595v1
Deep Learning links TP53 genotype to expression-defined transcriptional program in Acute Myeloid Leukemia #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687690v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687690v1
November 13, 2025 at 8:00 AM
Deep Learning links TP53 genotype to expression-defined transcriptional program in Acute Myeloid Leukemia #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687690v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687690v1
Single-cell Transcriptomic Profiling of Pancreatic Ductal Adenocarcinoma: Epithelial Reprogramming and Systemic Immune Exhaustion #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687730v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687730v1
November 13, 2025 at 8:00 AM
Single-cell Transcriptomic Profiling of Pancreatic Ductal Adenocarcinoma: Epithelial Reprogramming and Systemic Immune Exhaustion #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687730v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687730v1
Improved marker detection for rare population in single-cell transcriptomics through text mining-inspired scoring approach #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687759v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687759v1
November 13, 2025 at 8:00 AM
Improved marker detection for rare population in single-cell transcriptomics through text mining-inspired scoring approach #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687759v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687759v1
Cell Type Specific Inference of Perturbations in Synaptic Communication with MultiNeuronChat #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.11.687822v1
https://www.biorxiv.org/content/10.1101/2025.11.11.687822v1
November 13, 2025 at 8:00 AM
Cell Type Specific Inference of Perturbations in Synaptic Communication with MultiNeuronChat #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.11.687822v1
https://www.biorxiv.org/content/10.1101/2025.11.11.687822v1
Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.11.682326v1
https://www.biorxiv.org/content/10.1101/2025.11.11.682326v1
November 13, 2025 at 8:00 AM
Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.11.682326v1
https://www.biorxiv.org/content/10.1101/2025.11.11.682326v1
A self-organizing single-cell morphology circuit optimizes Podophrya collini predatory trap structure #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.12.688106v1
https://www.biorxiv.org/content/10.1101/2025.11.12.688106v1
November 13, 2025 at 8:00 AM
A self-organizing single-cell morphology circuit optimizes Podophrya collini predatory trap structure #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.12.688106v1
https://www.biorxiv.org/content/10.1101/2025.11.12.688106v1
Hybrid restricted master problem for Boolean matrix factorisation #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2509.06192
https://arxiv.org/abs/2509.06192
November 13, 2025 at 8:00 AM
Hybrid restricted master problem for Boolean matrix factorisation #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2509.06192
https://arxiv.org/abs/2509.06192
Multi-Scale Hybrid Modeling to Predict Cell Culture Process with Metabolic Phase Transitions #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2412.03883
https://arxiv.org/abs/2412.03883
November 13, 2025 at 8:00 AM
Multi-Scale Hybrid Modeling to Predict Cell Culture Process with Metabolic Phase Transitions #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2412.03883
https://arxiv.org/abs/2412.03883
Partial domain adaptation enables cross domain cell type annotation between scRNA-seq and snRNA-seq #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2511.08996
https://arxiv.org/abs/2511.08996
November 13, 2025 at 8:00 AM
Partial domain adaptation enables cross domain cell type annotation between scRNA-seq and snRNA-seq #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2511.08996
https://arxiv.org/abs/2511.08996
Powerful read processing with matchbox #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.09.685711v1
https://www.biorxiv.org/content/10.1101/2025.11.09.685711v1
November 12, 2025 at 5:01 PM
Powerful read processing with matchbox #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.09.685711v1
https://www.biorxiv.org/content/10.1101/2025.11.09.685711v1
The long-standing relationship between replication timing, gene expression, and chromatin accessibility is maintained in early mouse embryogenesis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687227v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687227v1
November 12, 2025 at 5:01 PM
The long-standing relationship between replication timing, gene expression, and chromatin accessibility is maintained in early mouse embryogenesis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687227v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687227v1
Quantum Generative Modeling of Single-Cell Transcriptomics: Capturing Gene-Gene and Cell-Cell Interactions #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2510.12776
https://arxiv.org/abs/2510.12776
November 12, 2025 at 5:00 PM
Quantum Generative Modeling of Single-Cell Transcriptomics: Capturing Gene-Gene and Cell-Cell Interactions #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2510.12776
https://arxiv.org/abs/2510.12776
Spinal cord regeneration deploys cell-type specific developmental and non-developmental strategies to restore neuron diversity #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687703v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687703v1
November 12, 2025 at 5:00 PM
Spinal cord regeneration deploys cell-type specific developmental and non-developmental strategies to restore neuron diversity #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687703v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687703v1
WNT inhibition primes the transcriptional landscape of mesoderm to initiate a phased ventricular cardiomyocyte specification programme #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.11.687613v1
https://www.biorxiv.org/content/10.1101/2025.11.11.687613v1
November 12, 2025 at 5:00 PM
WNT inhibition primes the transcriptional landscape of mesoderm to initiate a phased ventricular cardiomyocyte specification programme #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.11.687613v1
https://www.biorxiv.org/content/10.1101/2025.11.11.687613v1
The long-standing relationship between replication timing, gene expression, and chromatin accessibility is maintained in early mouse embryogenesis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687227v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687227v1
November 12, 2025 at 8:01 AM
The long-standing relationship between replication timing, gene expression, and chromatin accessibility is maintained in early mouse embryogenesis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.1101/2025.11.10.687227v1
https://www.biorxiv.org/content/10.1101/2025.11.10.687227v1
Clifti-GPT: Privacy-preserving federated fine-tuning and transferable inference of foundation models on clinical single-cell data #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7917089/latest
https://www.researchsquare.com/article/rs-7917089/latest
November 12, 2025 at 8:00 AM
Clifti-GPT: Privacy-preserving federated fine-tuning and transferable inference of foundation models on clinical single-cell data #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7917089/latest
https://www.researchsquare.com/article/rs-7917089/latest
6-Mercaptopurine inhibits HIV expression and improves CD4+ T cell immune function by downregulating mTOR #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7927164/latest
https://www.researchsquare.com/article/rs-7927164/latest
November 12, 2025 at 8:00 AM
6-Mercaptopurine inhibits HIV expression and improves CD4+ T cell immune function by downregulating mTOR #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7927164/latest
https://www.researchsquare.com/article/rs-7927164/latest