#NeuroDegeneration preprints
@prepub-neurodegen.bsky.social
feeds: biorxiv, medrxiv, arxiv.q-bio, arxiv.cs, arxiv.math, Research Square
regex: "(neurodegeneration|Alzheimer|Parkinson's|Huntington|amyloid lateral sclerosis|multiple sclerosis|Apoe4)"
All contacts to @willmacnair :)
regex: "(neurodegeneration|Alzheimer|Parkinson's|Huntington|amyloid lateral sclerosis|multiple sclerosis|Apoe4)"
All contacts to @willmacnair :)
A Multi-omic Atlas of Human Choroid Plexus in Alzheimer's Disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.23.690014v1
https://www.biorxiv.org/content/10.1101/2025.11.23.690014v1
November 25, 2025 at 5:02 PM
A Multi-omic Atlas of Human Choroid Plexus in Alzheimer's Disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.23.690014v1
https://www.biorxiv.org/content/10.1101/2025.11.23.690014v1
Fluid-Structure Interaction Dynamics of Cervical Lymphatic Vessel Pumping and Valvular Function #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689846v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689846v1
November 25, 2025 at 5:02 PM
Fluid-Structure Interaction Dynamics of Cervical Lymphatic Vessel Pumping and Valvular Function #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689846v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689846v1
Molecular mechanism decipher of Alzheimer's disease based on single-cell RNA-seq information #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.22.689872v1
https://www.biorxiv.org/content/10.1101/2025.11.22.689872v1
November 25, 2025 at 5:02 PM
Molecular mechanism decipher of Alzheimer's disease based on single-cell RNA-seq information #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.22.689872v1
https://www.biorxiv.org/content/10.1101/2025.11.22.689872v1
ApoE4 accelerates the condensate to amyloid transition of tau #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.22.689889v1
https://www.biorxiv.org/content/10.1101/2025.11.22.689889v1
November 25, 2025 at 5:02 PM
ApoE4 accelerates the condensate to amyloid transition of tau #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.22.689889v1
https://www.biorxiv.org/content/10.1101/2025.11.22.689889v1
Linking Cortical Morphology and Neurophysiological Dynamics in Parkinson's Disease #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7992155/latest
https://www.researchsquare.com/article/rs-7992155/latest
November 25, 2025 at 5:02 PM
Linking Cortical Morphology and Neurophysiological Dynamics in Parkinson's Disease #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7992155/latest
https://www.researchsquare.com/article/rs-7992155/latest
Potentially Avoidable Visits to the Emergency Department by Patients With Dementia at the End of Life – a Longitudinal Retrospective Study #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8184276/latest
https://www.researchsquare.com/article/rs-8184276/latest
November 25, 2025 at 5:02 PM
Potentially Avoidable Visits to the Emergency Department by Patients With Dementia at the End of Life – a Longitudinal Retrospective Study #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8184276/latest
https://www.researchsquare.com/article/rs-8184276/latest
3D Structural Hijacking of Pathological α-Synuclein Fibrillar Architectures by Carbon Dot Nanoeraser Prevents Neurodegeneration #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7997315/latest
https://www.researchsquare.com/article/rs-7997315/latest
November 25, 2025 at 5:02 PM
3D Structural Hijacking of Pathological α-Synuclein Fibrillar Architectures by Carbon Dot Nanoeraser Prevents Neurodegeneration #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7997315/latest
https://www.researchsquare.com/article/rs-7997315/latest
Detecting Discontinuities in the Topology of Alzheimers gene Co-expression #NeuroDegeneration 🧪🧠
https://arxiv.org/abs/2511.18238
https://arxiv.org/abs/2511.18238
November 25, 2025 at 8:02 AM
Detecting Discontinuities in the Topology of Alzheimers gene Co-expression #NeuroDegeneration 🧪🧠
https://arxiv.org/abs/2511.18238
https://arxiv.org/abs/2511.18238
Plasma Biomarkers of Neurodegeneration and Neuroinflammation among Middle- Aged Adults in Western India: Implications of Racial and Geographical Variability #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7788186/latest
https://www.researchsquare.com/article/rs-7788186/latest
November 25, 2025 at 8:02 AM
Plasma Biomarkers of Neurodegeneration and Neuroinflammation among Middle- Aged Adults in Western India: Implications of Racial and Geographical Variability #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7788186/latest
https://www.researchsquare.com/article/rs-7788186/latest
Molecular imaging of butyrylcholinesterase associated with amyloid-β plaques distinguishes 5XFAD from wild-type mice #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7491155/latest
https://www.researchsquare.com/article/rs-7491155/latest
November 25, 2025 at 8:02 AM
Molecular imaging of butyrylcholinesterase associated with amyloid-β plaques distinguishes 5XFAD from wild-type mice #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-7491155/latest
https://www.researchsquare.com/article/rs-7491155/latest
Blood-based biomarkers for Alzheimer’s disease: influence of kidney function #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8007954/latest
https://www.researchsquare.com/article/rs-8007954/latest
November 25, 2025 at 8:02 AM
Blood-based biomarkers for Alzheimer’s disease: influence of kidney function #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8007954/latest
https://www.researchsquare.com/article/rs-8007954/latest
DeNPRU-QM Responsive project: Prevalence of memory complaints in the absence of objective symptoms in clinical populations: systematic review update #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8165369/latest
https://www.researchsquare.com/article/rs-8165369/latest
November 25, 2025 at 8:02 AM
DeNPRU-QM Responsive project: Prevalence of memory complaints in the absence of objective symptoms in clinical populations: systematic review update #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-8165369/latest
https://www.researchsquare.com/article/rs-8165369/latest
TDP-43 suppression of ATP8A2 cryptic splicing implicates phosphatidylserine-driven neuroinflammation in ALS/FTD #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689833v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689833v1
November 25, 2025 at 8:02 AM
TDP-43 suppression of ATP8A2 cryptic splicing implicates phosphatidylserine-driven neuroinflammation in ALS/FTD #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689833v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689833v1
Blood-based Transcriptomics Reveal Sex- and Amyloid-Modulated Biology of Plasma pTau217 in Preclinical Alzheimer's Disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689770v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689770v1
November 25, 2025 at 8:02 AM
Blood-based Transcriptomics Reveal Sex- and Amyloid-Modulated Biology of Plasma pTau217 in Preclinical Alzheimer's Disease #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689770v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689770v1
Dynamic methylation changes in Alzheimers disease-related genes during mindfulness practice - a proof-of-concept study #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.17.688316v1
https://www.biorxiv.org/content/10.1101/2025.11.17.688316v1
November 24, 2025 at 5:01 PM
Dynamic methylation changes in Alzheimers disease-related genes during mindfulness practice - a proof-of-concept study #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.17.688316v1
https://www.biorxiv.org/content/10.1101/2025.11.17.688316v1
WWOX deficiency uncovers a cell-autonomous mechanism impairing myelin repair #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.22.689900v1
https://www.biorxiv.org/content/10.1101/2025.11.22.689900v1
November 24, 2025 at 5:01 PM
WWOX deficiency uncovers a cell-autonomous mechanism impairing myelin repair #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.22.689900v1
https://www.biorxiv.org/content/10.1101/2025.11.22.689900v1
Direct Measure of DNA Damage in Huntington Disease Reveals Elevated Oxidative Genotoxic Stress and Dysfunctional DNA Repair #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689804v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689804v1
November 24, 2025 at 8:02 AM
Direct Measure of DNA Damage in Huntington Disease Reveals Elevated Oxidative Genotoxic Stress and Dysfunctional DNA Repair #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689804v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689804v1
Sensitivity to TDP-43 loss and degradation resistance determine cryptic exon biomarker potential #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.23.689722v1
https://www.biorxiv.org/content/10.1101/2025.11.23.689722v1
November 24, 2025 at 8:01 AM
Sensitivity to TDP-43 loss and degradation resistance determine cryptic exon biomarker potential #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.23.689722v1
https://www.biorxiv.org/content/10.1101/2025.11.23.689722v1
Forecasting Future Anatomies: Longitudinal Brain Mri-to-Mri Prediction #NeuroDegeneration 🧪🧠
https://arxiv.org/abs/2511.02558
https://arxiv.org/abs/2511.02558
November 24, 2025 at 8:01 AM
Forecasting Future Anatomies: Longitudinal Brain Mri-to-Mri Prediction #NeuroDegeneration 🧪🧠
https://arxiv.org/abs/2511.02558
https://arxiv.org/abs/2511.02558
Title: A Randomized Hybrid Type I Effectiveness-Implementation Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer (eREACH2): study protocol #NeuroDegeneration 🧪🧠
http://medrxiv.org/cgi/content/short/2025.11.19.25340515v1
http://medrxiv.org/cgi/content/short/2025.11.19.25340515v1
November 23, 2025 at 8:01 AM
Title: A Randomized Hybrid Type I Effectiveness-Implementation Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer (eREACH2): study protocol #NeuroDegeneration 🧪🧠
http://medrxiv.org/cgi/content/short/2025.11.19.25340515v1
http://medrxiv.org/cgi/content/short/2025.11.19.25340515v1
Diffusion tensor imaging analysis along the perivascular space suggests impaired glymphatic clearance in Lewy body dementia subtypes #NeuroDegeneration 🧪🧠
http://medrxiv.org/cgi/content/short/2025.11.21.25340741v1
http://medrxiv.org/cgi/content/short/2025.11.21.25340741v1
November 22, 2025 at 5:01 PM
Diffusion tensor imaging analysis along the perivascular space suggests impaired glymphatic clearance in Lewy body dementia subtypes #NeuroDegeneration 🧪🧠
http://medrxiv.org/cgi/content/short/2025.11.21.25340741v1
http://medrxiv.org/cgi/content/short/2025.11.21.25340741v1
Monopolar network mapping predicts tremor outcomes of deep brain stimulation in Parkinson's disease #NeuroDegeneration 🧪🧠
http://medrxiv.org/cgi/content/short/2025.11.18.25340336v1
http://medrxiv.org/cgi/content/short/2025.11.18.25340336v1
November 22, 2025 at 5:01 PM
Monopolar network mapping predicts tremor outcomes of deep brain stimulation in Parkinson's disease #NeuroDegeneration 🧪🧠
http://medrxiv.org/cgi/content/short/2025.11.18.25340336v1
http://medrxiv.org/cgi/content/short/2025.11.18.25340336v1
The unexpected dual role of S100A9 amyloid protein on neurodegeneration in progressive multiple sclerosis motor cortex #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689707v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689707v1
November 22, 2025 at 5:01 PM
The unexpected dual role of S100A9 amyloid protein on neurodegeneration in progressive multiple sclerosis motor cortex #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.21.689707v1
https://www.biorxiv.org/content/10.1101/2025.11.21.689707v1
Serum Exosomes from a Uniquely Defined Early-Adult Cohort Reprogram Endothelial Transcriptomes Linked to Alzheimer's Pathogenesis. #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.20.689131v1
https://www.biorxiv.org/content/10.1101/2025.11.20.689131v1
November 22, 2025 at 8:01 AM
Serum Exosomes from a Uniquely Defined Early-Adult Cohort Reprogram Endothelial Transcriptomes Linked to Alzheimer's Pathogenesis. #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.20.689131v1
https://www.biorxiv.org/content/10.1101/2025.11.20.689131v1
Lipid droplets promote the aberrant liquid-liquid phase separation of alpha-synuclein leading to impaired energy homeostasis #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.20.689615v1
https://www.biorxiv.org/content/10.1101/2025.11.20.689615v1
November 22, 2025 at 8:01 AM
Lipid droplets promote the aberrant liquid-liquid phase separation of alpha-synuclein leading to impaired energy homeostasis #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.11.20.689615v1
https://www.biorxiv.org/content/10.1101/2025.11.20.689615v1