PreOperative Performance
banner
preoperative.bsky.social
PreOperative Performance
@preoperative.bsky.social
Anisotropic diffusion phantom technology

Neuroimaging reference standards for DTI,
data harmonisation, & QC solutions for imaging biomarker studies 🧠

✉️ contact@preoperativeperformance.com
Sharing work presented at the @esmrmb.bsky.social meeting in Marseille earlier this month, demonstrating our anisotropic diffusion phantom’s utility with higher-order tensor diffusion data models.

#Neuroscience #neuro #diffusionMRI #mri #dki #ESMRMB2025
October 20, 2025 at 8:04 PM
PreOperative Performance is delighted to attend the International Society of Tractography meeting in Bordeaux this week!

Say hello, DM or email

✉️: contact@preoperativeperformance.com

@tractography.bsky.social
October 14, 2025 at 12:56 PM
Some last scenes from near Marseille’s Vieux Port. Marseille was founded ~ 600BCE by Phoenician sailors and despite modern infrastructure requirements has wonderfully preserved layers of history.
October 12, 2025 at 9:02 AM
Thank you @esmrmb.bsky.social and thank you Marseille!

This was a greatly enjoyable meeting and I was delighted to see sessions dedicated to the importance of medical imaging quality (control & assurance) and reference standards.

(1/2)
October 12, 2025 at 9:00 AM
October 10, 2025 at 11:35 AM
Day 3 of #ESMRMB2025 begins shortly. It’s poster day!

In poster PG353 PreOperative Performance’s technology is applied to higher order tensor models of diffusion MRI data which can resolve complex neural architecture such as areas with crossing fibers.

(1/3)
October 10, 2025 at 8:21 AM
Join us at the preclinical imaging workshop session on Wednesday 8th at #ESMRMB meeting in Marseille.

(4/4)
October 6, 2025 at 8:15 PM
Preclinical imaging, including studies of ex-vivo tissue and organoid models, play a critical role in advancing MR imaging research by providing the means to explore the biological underpinnings of disease, refine imaging techniques and uncover insights…

🧵1/n
October 6, 2025 at 8:15 PM
We’re looking forward to attending #ESMRMB 2025 from October 8-11th
🧠

We look forward to meeting old friends and new and engaging in discussions about our anisotropic diffusion phantom technology. We are delighted to share that our technology will feature in the scientific program.

1/2
September 29, 2025 at 3:54 PM
Through use of PreOperative Performance’s phantom technology, we can explain tractography performance and determine the resolvability of tracts that can be achieved given their sizes, specific to the MR system and protocol used.

8/8
August 25, 2025 at 1:47 PM
The 3T data quality and protocol resulted in well-defined tracts (all 6 with 3 varying diameters ) when seed-based probabilistic tractography was performed. Multiple seeds were only required for the thinner bundles.

6/8
August 25, 2025 at 1:47 PM
In this diagram we show a comparison of results for fitting the tensor model to data collected at 2 field strengths and the resulting tractography.

3/8
August 25, 2025 at 1:47 PM
Imaging at 1.5T is not without its advantages, there are less distortions at lower field and some patients with implanted medical devices (such as cochlear implants) may be conditionally scanned at 1.5T and not at higher field strengths.

2/8
August 25, 2025 at 1:47 PM
MR imaging at 1.5T vs 3T have different advantages. 🧠

Aside from cost considerations, imaging at 3T delivers higher signal to noise (SNR) enabling increased spatial resolution, critical for identification of smaller white matter tracts and changes that may result from injury or disease.

1/8
August 25, 2025 at 1:47 PM
August 17, 2025 at 7:19 PM
The scan was performed on a 3T
#MAGNUS system by GE Healthcare with high in-plane isotropic resolution (0.937 mm) and with 2.0mm slices, 3 non-diffusion weighted volumes and 50 gradient directions (b-value = 1000 s/mm2 ).

(4/4)
August 1, 2025 at 2:25 PM
We used FSL's bedpost and Fdt with spherical mask seed points (shown in yellow) and termination sphere masks shown in red. The 3D rendering shows the result as a mask.

(3/4)
August 1, 2025 at 2:23 PM
Note: the small bifurcating bundle into the S-I plane is 2.9 mm and the spatial resolution in S-I is 2.0 mm. The resulting tract density map is color-coded where the intensity of the blue corresponds to streamline density, providing a voxel-wise estimate of confidence.

(2/4)
August 1, 2025 at 2:23 PM
A post on visualizing white matter bifurcations using diffusion analysis:
🧠

We show that using the diffusion model and seed-based #tractography, we are able to delineate the full bifurcating module of a bifurcating module in our phantom POP-0005 with dimensions as given.

🧵(1/4)
August 1, 2025 at 2:22 PM
Image shows max projection seed-based #tractography results, color-coded by direction: Anterior-Posterior (AP) in green and Right-Left (RL) in red and overlayed on the mean_S0 samples image.

(2/3)
July 29, 2025 at 1:35 PM
This image shows 3 pairs of crossing white matter simulating modules with 3 different bundle diameters from our phantom POP-0005. Note that the bundles with smallest diameter are sub-voxel dimensions.

🧵(1/3)
July 29, 2025 at 1:34 PM
We show the 3-direction vector image (RGB) modulated and clipped by FA values between 0.15-1.0, overlayed on a b=0 image. As the resolution increases along a dimension, the partial volume effects decrease so the FA increases and more color-coded voxels appear in the fiber bundle.

3/3
July 22, 2025 at 3:16 PM
Three scans on 3 different 3T scanners were performed at varying resolutions
Scan A: 2.5 mm isotropic,
Scan B: 2.0 mm isotropic and
Scan C: 0.937 mm isotropic in-plane (axially) and 3.0 mm through-slice.

2/3
July 22, 2025 at 3:16 PM
A short thread on partial voxel effects in MR imaging:

This figure shows the effects of partial volume on FA on 2 white matter simulating modules with diameter 5.9 mm (along S-I, in green) and 4.3 mm (along R-L, in red).

1/3

#mri #dmri #neurorad
July 22, 2025 at 3:15 PM
🚨 Publication announcement!

We’re delighted to share the news that our anisotropic diffusion phantom features in the literature, in a study harmonising DTI metrics acquired across different #MRI systems, controlling for variables including repeat scan, vendor, and MPGs.

(1/n)
March 25, 2025 at 8:54 PM