SMT
pp0196.bsky.social
SMT
@pp0196.bsky.social
Sequences and consequences.



Credit Pic : Cellular landscape cross-section through a eukaryotic cell, by Evan Ingersoll
CSS only ? which other JS libraries ?
November 12, 2025 at 8:26 PM
The goal is to, similar to basilik, have a uniform way to declare rix environment dependencies in a package. This is to use rix for more general external dependencies management in packages (not projects) e.g say my package requires bcftools 1.21 that I will acquire through nix
November 9, 2025 at 1:38 PM
it can be installed from conda or pip, so need to just make sure on of them is installed reliably with rix. My question would be, what would be the recommended pattern for declaring rix environments in packages, should one put the nix derivations in inst/rix or stick to code ?
November 8, 2025 at 12:56 PM
@josiahparry.com why not build it in this framework github.com/luminal-ai/l... and expose it to R and add an oxidized backend to the R transpiling options in r-xla github.com/r-xla/anvil/...
November 7, 2025 at 11:09 PM
@brodriguesco.bsky.social i guess rix/rixpress already have implicitly something like this, but let it make it more explicit: using rix for package external dependencies declaration along the lines of basilisk in Bioconductor github.com/bioconductor.... I would be very happy to get rid of pixi/pip
November 7, 2025 at 10:29 PM
rixpress is a R based proposition for so called multilingual pipelines (in reality most of the time why not just wrap what is needed via reticulate or similar for other languages) brodrigues.co/posts/2025-1...
Orchestrating Polyglot, Reproducible Data Science with Nix and {rixpress} – Econometrics and Free Software
brodrigues.co
November 6, 2025 at 6:23 PM
Sometimes one need more control than just letting lexical scoping rule, one reason would be to avoid size effects in caller environment (using `source` with an environment parameter). Other than the more general questions around environment and Namespaces henrikbengtsson.github.io/environments...
How objects are found by package functions
henrikbengtsson.github.io
November 5, 2025 at 2:31 PM
If you add to this the terrible docs you can understand the nihilist and p(y)edantic (pun intended) type annotations drive
November 3, 2025 at 3:50 PM
Reposted by SMT
A significant OpenZL theme is genomic data compression. Users are eager for benchmarks against CRAM, FASTA, FASTQ, SAM, and VCF. It shows promise for tackling large datasets, especially challenging nanopore data. #Genomics 2/5
October 7, 2025 at 7:00 PM
i ve try it out using uv , it appears that the free threaded python is a significant ABI change github.com/rstudio/reti...
find libpython for uv threaded python venvs by sounkou-bioinfo · Pull Request #1857 · rstudio/reticulate
github.com
October 26, 2025 at 12:30 AM
is there some container setup to test reticulate against specific CPython builds (i can see that the libpython is linked against in src) ? Disclosure i am not a (direct) reticulate even though i should become one pretty soon :D
October 25, 2025 at 8:57 PM