Penn Neurodegeneration Genomics Center
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pngc.bsky.social
Penn Neurodegeneration Genomics Center
@pngc.bsky.social
110 followers 100 following 10 posts
We study the genetics of Alzheimer’s Disease through genotyping and sequencing technologies

Check out our most recent publications and blog ⬇️
https://www.penn-ngc.org/
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pngc.bsky.social
(5/5) In October, a preprint was released reintroducing NIAGADS, the National Institute on Aging’s data repository for Alzheimer's Disease research, hosting extensive genetic data and supporting global collaborations to advance research and treatment

www.medrxiv.org/content/10.1...
NIAGADS: A Comprehensive National Data Repository for Alzheimer’s Disease and Related Dementia Genetics and Genomics Research
NIAGADS is the National Institute on Aging (NIA) designated national data repository for human genetics research on Alzheimer’s Disease and related dementia (ADRD). NIAGADS maintains a high-quality…
www.medrxiv.org
April 17, 2025 at 4:20 PM
pngc.bsky.social
(4/5) Dr. Kaylyn Clark graduated with a degree in Genomics and Computational Biology from @upenngcb.bsky.social
April 17, 2025 at 4:20 PM
pngc.bsky.social
(3/5) Back in July, our own Dr. Lee , presented his plenary session, "Neuropathology in a Multidisciplinary Age” #AAIC24
April 17, 2025 at 4:20 PM
pngc.bsky.social
(2/5) PNGC researchers presented a bioinformatics strategy for joint-calling 20,504 whole-exome sequencing samples across multiple studies and sequencing centers, successfully accounting for batch effects and generating high-quality variant data

www.nature.com/articles/s41...
Human whole-exome genotype data for Alzheimer’s disease - Nature Communications
The heterogeneity of whole-exome sequencing (WES) data generation methods presents a challenge to joint analysis. Here, the authors present a bioinformatics strategy to generate high-quality data…
www.nature.com
April 17, 2025 at 4:20 PM