Lisa Smith
@plantylisasmith.bsky.social
Plant geneticist/molecular biologist/developmental biologist. Senior lecturer at Uni of Sheffield. She/her. 🇦🇺🇳🇿🇬🇧🌱🌿🌾🍄
Fully funded for home students for 4 years. International students can apply, but please be aware the Doctoral Training Programme only covers a stipend and student fees - it doesn't cover your visa, NHS surcharge, travel insurance or travel.
November 17, 2025 at 6:21 AM
Fully funded for home students for 4 years. International students can apply, but please be aware the Doctoral Training Programme only covers a stipend and student fees - it doesn't cover your visa, NHS surcharge, travel insurance or travel.
Jodie's sculpture is amazing! So great to have Sheffield plant scientists' work on display in London. Well done, Jess and Jodie!
July 26, 2025 at 7:28 AM
Jodie's sculpture is amazing! So great to have Sheffield plant scientists' work on display in London. Well done, Jess and Jodie!
In 2024, the main paper from our collaboration with Frank's group appeared on BioRxiv:
www.biorxiv.org/content/10.1...
With this week's BioRxiv submission, that's four exciting papers from what was, in some respects, a failed experiment.
www.biorxiv.org/content/10.1...
With this week's BioRxiv submission, that's four exciting papers from what was, in some respects, a failed experiment.
Multi-generational biotic stress increases the rate of spontaneous epimutations in a ROS1-dependent manner
Mistakes in the maintenance of CG methylation are a source of spontaneous epimutations in plants that can be inherited across generations. The extent to which these stochastic events are affected by p...
www.biorxiv.org
June 6, 2025 at 3:45 PM
In 2024, the main paper from our collaboration with Frank's group appeared on BioRxiv:
www.biorxiv.org/content/10.1...
With this week's BioRxiv submission, that's four exciting papers from what was, in some respects, a failed experiment.
www.biorxiv.org/content/10.1...
With this week's BioRxiv submission, that's four exciting papers from what was, in some respects, a failed experiment.
A second paper followed in 2023 using epigenetic rather than genomic data from some of our lines, this time from our collaboration with Frank Johannes and his lab:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
An evolutionary epigenetic clock in plants
A fast-ticking evolutionary epigenetic clock in plants facilitates phylogenetic insights into the recent past.
www.science.org
June 6, 2025 at 3:45 PM
A second paper followed in 2023 using epigenetic rather than genomic data from some of our lines, this time from our collaboration with Frank Johannes and his lab:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
In 2021, the first paper using some of our data was published thanks to @labschneeberger.bsky.social sharing genome sequencing data from our wild-type plants with @hendersi.bsky.social.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
The genetic and epigenetic landscape of the Arabidopsis centromeres
Long-read sequencing and assembly of Arabidopsis centromeres reveals their genetic and epigenetic topography.
www.science.org
June 6, 2025 at 3:45 PM
In 2021, the first paper using some of our data was published thanks to @labschneeberger.bsky.social sharing genome sequencing data from our wild-type plants with @hendersi.bsky.social.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
However, in 2016/7 we had started collaborating with @labschneeberger.bsky.social and Frank Johannes. Our failure to induce priming fortunately didn't affect what they wanted to look at in the data.
June 6, 2025 at 3:45 PM
However, in 2016/7 we had started collaborating with @labschneeberger.bsky.social and Frank Johannes. Our failure to induce priming fortunately didn't affect what they wanted to look at in the data.
10 generations turned into 15 as we grew the plants from 2014 to 2018. We checked priming in 2014 after one generation and were satisfied our protocol worked.
Then in 2018, we checked the priming after ten generations and there was no transgenerational priming. Four years of work and no priming...
Then in 2018, we checked the priming after ten generations and there was no transgenerational priming. Four years of work and no priming...
June 6, 2025 at 3:45 PM
10 generations turned into 15 as we grew the plants from 2014 to 2018. We checked priming in 2014 after one generation and were satisfied our protocol worked.
Then in 2018, we checked the priming after ten generations and there was no transgenerational priming. Four years of work and no priming...
Then in 2018, we checked the priming after ten generations and there was no transgenerational priming. Four years of work and no priming...
In 2013, I joined the Department of Animal and Plant Sciences at Sheffield, with @jurriaanton.bsky.social as a colleague. Jurr quickly persuaded me to join forces and start a multiple-generation stress experiment to see how long transgenerational priming would last after 10 generations of stress.
June 6, 2025 at 3:45 PM
In 2013, I joined the Department of Animal and Plant Sciences at Sheffield, with @jurriaanton.bsky.social as a colleague. Jurr quickly persuaded me to join forces and start a multiple-generation stress experiment to see how long transgenerational priming would last after 10 generations of stress.