@pkeukeleire.bsky.social
Reposted
Capture C identifies promoter interacting sequences. MPRA tests sequences for regulatory activity. Here, we combined them both to test sequences with their target promoter. Amazing work by @colinearnould.bsky.social, Pia Keukeleire, Martin Kircher and many others.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Capture-C MPRA: A high-throughput method to simultaneously characterize promoter interactions and regulatory activity
Cis regulatory elements (CREs) interact with their target promoters over long genomic distances and can be identified using chromatin conformation capture (3C) assays. Their regulatory activity can be...
www.biorxiv.org
June 15, 2025 at 6:29 PM
Capture C identifies promoter interacting sequences. MPRA tests sequences for regulatory activity. Here, we combined them both to test sequences with their target promoter. Amazing work by @colinearnould.bsky.social, Pia Keukeleire, Martin Kircher and many others.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...