@pietrobiobassani.bsky.social
5/
Turns out, PA-FGRS was associated with higher exposure to emotional neglect and abuse, especially in those without a depression diagnosis.
PGS showed no such pattern.
Turns out, PA-FGRS was associated with higher exposure to emotional neglect and abuse, especially in those without a depression diagnosis.
PGS showed no such pattern.
June 22, 2025 at 1:40 PM
5/
Turns out, PA-FGRS was associated with higher exposure to emotional neglect and abuse, especially in those without a depression diagnosis.
PGS showed no such pattern.
Turns out, PA-FGRS was associated with higher exposure to emotional neglect and abuse, especially in those without a depression diagnosis.
PGS showed no such pattern.
4/
We looked at two ways of measuring genetic risk:
🔹 Polygenic scores (PGS)—based on DNA markers
🔹 Family-based scores (PA-FGRS)—based on diagnoses in parents and siblings
Both predict depression—but only one predicted trauma exposure.
We looked at two ways of measuring genetic risk:
🔹 Polygenic scores (PGS)—based on DNA markers
🔹 Family-based scores (PA-FGRS)—based on diagnoses in parents and siblings
Both predict depression—but only one predicted trauma exposure.
June 22, 2025 at 1:40 PM
4/
We looked at two ways of measuring genetic risk:
🔹 Polygenic scores (PGS)—based on DNA markers
🔹 Family-based scores (PA-FGRS)—based on diagnoses in parents and siblings
Both predict depression—but only one predicted trauma exposure.
We looked at two ways of measuring genetic risk:
🔹 Polygenic scores (PGS)—based on DNA markers
🔹 Family-based scores (PA-FGRS)—based on diagnoses in parents and siblings
Both predict depression—but only one predicted trauma exposure.
