It wasn’t a full replacement, but a “bridge organ” to support the patient’s own liver. With global donor shortages, this could be a glimpse into the future of transplants.

Call it Xenotransplantation 2.0—and yes, pigs might save lives.

#Biotech #LiverTransplant

🧪 The pig liver:

Secreted bile
Produced albumin
Showed no major rejection
Had 6 gene edits for compatibility

"This opens the door to new therapeutic targets focused on early brain changes, before cognition declines." —Dr. Lea Grinberg, UCSF

This could explain why non-cognitive symptoms like sleep issues, anxiety, and depression show up decades before memory loss.
🧪 Study published March 26 in Alzheimer’s & Dementia.

Researchers analyzed brain tissue from the Substantia Nigra (resistant to AD) and Locus Coeruleus (highly vulnerable) and found a major clue: LC neurons are cholesterol-hungry and express more LDLR—possibly making them easier targets for toxic amyloid-beta.

Japan sees 5,000+ spinal injury cases annually. This study marks the first human trial of iPS stem cells for spinal injury treatment.

A hopeful moment in biotech and regenerative healthcare.

Lead researcher Prof. Hideyuki Okano says the team hopes to move toward broader clinical trials.

This may open a new path for treating paralysis.

One elderly patient can now stand without support and has begun walking practice — a major recovery milestone, per NHK.

🧬 In a small trial: • 4 patients received 2M+ neural stem cells
• 2 regained motor function
• 0 serious side effects after one year