Maryam Pezhouh MD MSc
@pezhouh.bsky.social
Pathologist, UCSD, mom, yogi, #UCSD, #GIPath #Pathology #Path
worst human ever!
March 5, 2025 at 5:37 AM
worst human ever!
Reposted by Maryam Pezhouh MD MSc
This is a microcystic/reticular schwannoma. They have NONO::TFE3 fusions. Karen Fritchie (CCF) wrote up a nice series. pubmed.ncbi.nlm.nih.gov/37468653/
Novel NONO::TFE3 fusion and ALK co-expression identified in a subset of cutaneous microcystic/reticular schwannoma - PubMed
Microcystic/reticular schwannoma (MRS) is a benign variant of schwannoma with a predilection for the gastrointestinal tract and skin. To date, genetic characterization of this tumor is limited. Prompt...
pubmed.ncbi.nlm.nih.gov
February 12, 2025 at 9:01 PM
This is a microcystic/reticular schwannoma. They have NONO::TFE3 fusions. Karen Fritchie (CCF) wrote up a nice series. pubmed.ncbi.nlm.nih.gov/37468653/
Reposted by Maryam Pezhouh MD MSc
Why “not quite right”? It’s got thick, hyalinized vessels and some compact area with palisading. The cells have gorgeous processes, creating a strikingly “reticular” appearance. And it is TFE3-positive.
February 12, 2025 at 8:59 PM
Why “not quite right”? It’s got thick, hyalinized vessels and some compact area with palisading. The cells have gorgeous processes, creating a strikingly “reticular” appearance. And it is TFE3-positive.
Reposted by Maryam Pezhouh MD MSc
By IHC it is diffusely CD34-pos, shows strong nuclear WT1, and contains scattered desmin-pos cells. This is a superficial CD34-positive fibroblastic tumor. Very low grade tumor, often with PRDM10 fusions. Jody Carter, now in Edmonton, wrote this paper. pubmed.ncbi.nlm.nih.gov/23887307/
February 5, 2025 at 7:12 PM
By IHC it is diffusely CD34-pos, shows strong nuclear WT1, and contains scattered desmin-pos cells. This is a superficial CD34-positive fibroblastic tumor. Very low grade tumor, often with PRDM10 fusions. Jody Carter, now in Edmonton, wrote this paper. pubmed.ncbi.nlm.nih.gov/23887307/