Per Svensson
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persvensson.bsky.social
Per Svensson
@persvensson.bsky.social
MD, FESC, Senior lecturer, Karolinska Institutet
Agree. We found similar for incident cvd in twins - higher crea good/ but higher cyst c bad. But time for a redo with more events

www.ahajournals.org/doi/full/10....
Cystatin C Predicts Incident Cardiovascular Disease in Twins | Journal of the American Heart Association
BackgroundCystatin C is associated with both renal function and atherosclerotic cardiovascular disease (ASCVD). We have previously shown a genetic correlation between cystatin C and prevalent ASCVD. T...
www.ahajournals.org
April 3, 2025 at 4:05 PM
It was always on my mind🎵
April 1, 2025 at 8:38 AM
Wow ! Amazing!
With Steve Nieve ?
Wonder if the rest of the attractions still standing?

open.spotify.com/track/5PtUxC...
Spotify
open.spotify.com
March 9, 2025 at 3:56 PM
Yes but still kind of reassuring (if you for some reason want to wait with tx) that you needed to randomize 1600 pts with these BP levels and follow them for 24 months to see an effect. Although looking at the p-values in retrospect it probably should have been stopped earlier….
February 17, 2025 at 2:30 PM
Please see DM for tip

Yes and the BP levels at which they randomized quite staggering with todays perspective, SBP 180-230…., 175 was nt worthwhile I guess😉. The era of 100 plus age is normal😉
February 17, 2025 at 5:44 AM
In Sweden, that is...
So maybe we should have kept to supine
February 16, 2025 at 2:04 PM
Not like you did that I’m aware of.
But if you look on older RCTs they used supine BP. Like this one

www.thelancet.com/journals/lan...
Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension)
Although the benefits of antihypertensive treatment in
www.thelancet.com
February 16, 2025 at 12:45 PM
Interesting !
Used to be the Swedish standard until we adopted international standards (sitting) 10-15 years ago 😉
February 16, 2025 at 5:53 AM