Perle Guarino-Vignon
perlegv.bsky.social
Perle Guarino-Vignon
@perlegv.bsky.social
just a pos-doc gal running some code in a corner of Paris
Bioinformatics, microbiome in human, ancient DNA
she/her
Reposted by Perle Guarino-Vignon
🌎👩‍🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵

Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.

doi.org/10.1101/2024...
September 3, 2025 at 8:39 AM
Reposted by Perle Guarino-Vignon
The Mutation That Traveled Through Time
www.anthropology.net/p/the-mutati...
The Mutation That Traveled Through Time
How an ancient gene variant helped humans survive past pandemics—and shields some today from HIV
www.anthropology.net
May 10, 2025 at 8:17 AM
With all the sun we had in Paris, I want to share pics I took of two birds I strongly associate with spring and summer.
.
Read the Alt text to know more about them (in French and English)
April 14, 2025 at 6:46 PM
Reposted by Perle Guarino-Vignon
Still relevant today... Counter the weaponization of genetics research by extremists.
Geneticists must rethink how they conduct their research and how they communicate results. www.nature.com/articles/d41... @sramach.bsky.social @cschlebu.bsky.social @haam-community.bsky.social #genetics #research
Counter the weaponization of genetics research by extremists
Geneticists must rethink how they conduct their research and how they communicate results.
www.nature.com
March 25, 2025 at 9:52 AM
Reposted by Perle Guarino-Vignon
"I study animals from the past, and they should stay in the past," as I said in this interview, and "the idea that they can fix that [the extinction crisis] with gene editing is missing the big picture.”
www.scientificamerican.com/article/comp...
Company Seeking to Resurrect the Woolly Mammoth Creates a 'Woolly Mouse'
On their quest to bring back the extinct woolly mammoth, Colossal Biosciences has developed the woolly mouse
www.scientificamerican.com
March 4, 2025 at 9:27 PM
Reposted by Perle Guarino-Vignon
The International Day of Women and Girls in Science is always a bittersweet one: it is time for awareness of the benefits of gender equality to advance science, but when we are promoting scientific careers... what careers are those?
February 12, 2025 at 10:42 AM
Reposted by Perle Guarino-Vignon
A l'occasion de la Journée des femmes et des filles en science, le CRSA tient à mettre à l'honneur ses ingénieures, techniciennes, doctorantes, post-doctorantes, enseignantes -chercheuses, chercheuses et gestionnaires 👩🏼‍🔬👩🏻👩🏽‍🎓
February 11, 2025 at 3:56 PM
Reposted by Perle Guarino-Vignon
Between 2019 and 2023, researchers paid $8.968 billion to make papers open access. Imagine what else could be done with this money if it wasnt paid to for profit publishing companies...
👉 arxiv.org/abs/2407.16551
January 27, 2025 at 12:33 AM
Reposted by Perle Guarino-Vignon
If anyone happens to need it this week for...reasons...this is the best graphic on the complexity of human sex determination I've ever seen. I use it in an undergrad course on gene regulatory mechanisms. Shoutout to @unamandita.bsky.social!

www.scientificamerican.com/article/beyo...
Beyond XX and XY: The Extraordinary Complexity of Sex Determination
A host of factors figure into whether someone is female, male or somewhere in between
www.scientificamerican.com
January 21, 2025 at 8:58 PM
I don't understand researcher using IA art to promote their work, when the discussion in academia about plagiarism, citation, giving credits to people works and idea is so important
January 22, 2025 at 10:00 AM
"Genetic data are not produced in a political vacuum, can be used and abused in political agenda, and have serious implications in the treatment in marginalized communities [...] whole lives are condensed to a few data points, an inherently dehumanizing process"
The ancestral genome’s tale
Narratives that invoke ancient DNA must be crafted with care, argues an archaeologist
www.science.org
January 22, 2025 at 9:51 AM
Reading this paper, I felt like sharing my veggie journey here. So here it is, my first Bluesky thread ! 1/X
Sustainability of animal-sourced foods and plant-based alternatives | PNAS
Sustainability of animal-sourced foods and plant-based alternatives
www.pnas.org
December 6, 2024 at 10:48 AM
A fascinating read
"the factors predicting high ages in regions around the world consist of a lack of birth certificates, high poverty levels, and fewer 90-year-olds. [...] shoddy paperwork and pension fraud [...] are better explanations for blue zones than anything else."
The Longevity Hot Spots That Weren’t
Our culture has become obsessed with “blue zones,” where people purportedly live longer. But does the underlying research stand up to scrutiny?
newrepublic.com
December 3, 2024 at 4:07 PM
Reposted by Perle Guarino-Vignon
I am happy to share my latest article published on
@uk.theconversation.com, written for a broad audience, where I summarise our review about the Denisovans! 🧬✨ Discover their fascinating genetics and how they shaped human history.

theconversation.com/their-dna-su...
Their DNA survives in diverse populations across the world – but who were the Denisovans?
The discovery of a finger bone in a cave in Siberia some 15 years ago kicked off a race to unravel the mysteries of an entirely new group of humanoids.
theconversation.com
November 27, 2024 at 11:41 AM
Reposted by Perle Guarino-Vignon
www.nature.com/articles/s41...
My friend @chrischirp.bsky.social pointed out I can't just lazily paste links to a paper of interest without any explanation! We all buy into gut microbiota shaping immune populations and programmes, but this study adds huge granularity, by anatomical region and subset
November 27, 2024 at 8:13 AM