Paul Howard
@paulhoward.bsky.social
Consultant in Palliative Medicine (Isle of Wight, UK); Palliative Care Formulary Editor (neuropharmacology sections)
Apixaban is often the DOAC of choice for cancer-related VTE because its safer than rivaroxaban (quoted thread)
Its also cheaper in UK.
Further, this systematic review found reducing apixaban to 2.5mg BD after 6 months reduced bleeding risk without increasing VTE recurrence
doi.org/10.1016/j.th...
Its also cheaper in UK.
Further, this systematic review found reducing apixaban to 2.5mg BD after 6 months reduced bleeding risk without increasing VTE recurrence
doi.org/10.1016/j.th...
October 25, 2025 at 7:53 AM
Apixaban is often the DOAC of choice for cancer-related VTE because its safer than rivaroxaban (quoted thread)
Its also cheaper in UK.
Further, this systematic review found reducing apixaban to 2.5mg BD after 6 months reduced bleeding risk without increasing VTE recurrence
doi.org/10.1016/j.th...
Its also cheaper in UK.
Further, this systematic review found reducing apixaban to 2.5mg BD after 6 months reduced bleeding risk without increasing VTE recurrence
doi.org/10.1016/j.th...
I thought two things were particularly interesting. Firstly, the subset who responded to one and not the other - most of these responded to lidocaine and not oxcarb. This might reflect lidocaine having other actions of possible analgesic relevance (e.g. anti-inflammatory and glycinergic effects)
January 9, 2025 at 7:56 AM
I thought two things were particularly interesting. Firstly, the subset who responded to one and not the other - most of these responded to lidocaine and not oxcarb. This might reflect lidocaine having other actions of possible analgesic relevance (e.g. anti-inflammatory and glycinergic effects)
Community access to Palliative Medications;
My colleagues have just returned from an acute severe pain crisis not responding to opioids
They're now comfortable because we took 2nd line drugs straight out from our community stock cupboard.
Easy yet essential.
Why isn't this routine everywhere?
My colleagues have just returned from an acute severe pain crisis not responding to opioids
They're now comfortable because we took 2nd line drugs straight out from our community stock cupboard.
Easy yet essential.
Why isn't this routine everywhere?
August 28, 2024 at 8:45 PM
Community access to Palliative Medications;
My colleagues have just returned from an acute severe pain crisis not responding to opioids
They're now comfortable because we took 2nd line drugs straight out from our community stock cupboard.
Easy yet essential.
Why isn't this routine everywhere?
My colleagues have just returned from an acute severe pain crisis not responding to opioids
They're now comfortable because we took 2nd line drugs straight out from our community stock cupboard.
Easy yet essential.
Why isn't this routine everywhere?