Paul Young
@paulgyoung.bsky.social
MD-PhD student at Tri-I. PhD candidate in Jue Chen’s lab @Rockefeller. I like to appreciate the little things (membrane protein biophysics and structural bio).
Reposted by Paul Young
How does spontaneous memory reinstatement at rest relate to episodic memory during development? And how do early experiences influence neural mechanisms of episodic memory encoding and reinstatement? New preprint! www.biorxiv.org/content/10.1...
Spontaneous reinstatement of episodic memories in the developing human brain
The hippocampus supports episodic memories in development, and yet how the brain stabilizes these memories determines their long-term accessibility. This study examined how episodic memories formed in...
www.biorxiv.org
September 16, 2025 at 12:19 PM
How does spontaneous memory reinstatement at rest relate to episodic memory during development? And how do early experiences influence neural mechanisms of episodic memory encoding and reinstatement? New preprint! www.biorxiv.org/content/10.1...
Happy to have this work out! Using cryo-EM and electrophysiology, we clarify the mechanism of a small molecule inhibitor of CFTR that could have some important clinical applications.
rdcu.be/eyVyq
rdcu.be/eyVyq
Structure of CFTR bound to (R)-BPO-27 unveils a pore-blockage mechanism
Nature Communications - Hyperactivation of the cystic fibrosis transmembrane conductance regulator (CFTR) is central to the pathogenesis of secretory diarrheas and autosomal dominant polycystic...
rdcu.be
August 2, 2025 at 4:31 PM
Happy to have this work out! Using cryo-EM and electrophysiology, we clarify the mechanism of a small molecule inhibitor of CFTR that could have some important clinical applications.
rdcu.be/eyVyq
rdcu.be/eyVyq
Reposted by Paul Young
I have noticed that many cool people are starting labs at Ohio State right now. I've decided to follow their lead.
Soon, my lab will be moving to Ohio State as well.
You can learn more about our recent and upcoming work here: www.cogdevlab.org
Soon, my lab will be moving to Ohio State as well.
You can learn more about our recent and upcoming work here: www.cogdevlab.org
June 25, 2025 at 1:44 PM
I have noticed that many cool people are starting labs at Ohio State right now. I've decided to follow their lead.
Soon, my lab will be moving to Ohio State as well.
You can learn more about our recent and upcoming work here: www.cogdevlab.org
Soon, my lab will be moving to Ohio State as well.
You can learn more about our recent and upcoming work here: www.cogdevlab.org
Reposted by Paul Young
Incredibly excited and grateful to share that I’ll be starting a lab at The Ohio State University this(!) fall! My lab will study human learning and memory, with related interests in sleep, stress, and time perception. More info soon, but do get in touch if you’re interested in joining!
June 24, 2025 at 3:03 PM
Incredibly excited and grateful to share that I’ll be starting a lab at The Ohio State University this(!) fall! My lab will study human learning and memory, with related interests in sleep, stress, and time perception. More info soon, but do get in touch if you’re interested in joining!
Reposted by Paul Young
Why do we not remember being a baby? One idea is that the hippocampus, which is essential for episodic memory in adults, is too immature to form individual memories in infancy. We tested this using awake infant fMRI, new in @science.org #ScienceResearch www.science.org/doi/10.1126/...
Hippocampal encoding of memories in human infants
Humans lack memories for specific events from the first few years of life. We investigated the mechanistic basis of this infantile amnesia by scanning the brains of awake infants with functional magne...
www.science.org
March 20, 2025 at 6:37 PM
Why do we not remember being a baby? One idea is that the hippocampus, which is essential for episodic memory in adults, is too immature to form individual memories in infancy. We tested this using awake infant fMRI, new in @science.org #ScienceResearch www.science.org/doi/10.1126/...
Reposted by Paul Young
We will keep fighting and standing up for science.
March 11, 2025 at 3:17 PM
We will keep fighting and standing up for science.
Reposted by Paul Young
I am grateful that right now I am part of a very supportive community — though at the same time, it is painful to know that I’m not alone.
March 11, 2025 at 3:17 PM
I am grateful that right now I am part of a very supportive community — though at the same time, it is painful to know that I’m not alone.
Reposted by Paul Young
Last year, I was overjoyed to receive an NIH NRSA fellowship to study toddler brains and caregiving effects on memory at Columbia. Last night, my grant was terminated.
March 11, 2025 at 3:17 PM
Last year, I was overjoyed to receive an NIH NRSA fellowship to study toddler brains and caregiving effects on memory at Columbia. Last night, my grant was terminated.