Paul Rainey
@paulbrainey.bsky.social
Evolutionary geneticist working with microbes. Absorbed by Major Evolutionary Transitions. Fighting the decline to grumpiness. MPI for Evolutionary Biology, Plön, Germany & ESPCI, Paris, France.
I agree, but then there is reality. It would be super if there were more academic positions, but the current system seems fully expanded. I'm behind your wish to fight, but without major societal shifts, I can't see progres. It comes down to money and priorities. Politics 😥
October 31, 2025 at 6:17 PM
I agree, but then there is reality. It would be super if there were more academic positions, but the current system seems fully expanded. I'm behind your wish to fight, but without major societal shifts, I can't see progres. It comes down to money and priorities. Politics 😥
Agree. But at a golbal level, training too many PhD students -- many of whom desire an academic position -- is problematic if academic positions are in short supply.
October 31, 2025 at 5:33 PM
Agree. But at a golbal level, training too many PhD students -- many of whom desire an academic position -- is problematic if academic positions are in short supply.
Totally agreement: we do state that people acheiving doctorate-level training have a multiplicity of career paths that extend well beyond those offered by the standard academic route. And these options are in no way lesser paths. 🙏 for engagement.
October 31, 2025 at 5:29 PM
Totally agreement: we do state that people acheiving doctorate-level training have a multiplicity of career paths that extend well beyond those offered by the standard academic route. And these options are in no way lesser paths. 🙏 for engagement.
thank you. all credit to yansong who just kept on keeping on. we knew that something in the compost juice was transfering the GIs, but the jumbo phage, being much less numerous cf other lytic phages also present in the juice, was a real challenge to find. But we played a few tricks and we go it!
October 29, 2025 at 7:21 AM
thank you. all credit to yansong who just kept on keeping on. we knew that something in the compost juice was transfering the GIs, but the jumbo phage, being much less numerous cf other lytic phages also present in the juice, was a real challenge to find. But we played a few tricks and we go it!
Unlikely to me too. Assuming the diffs are real (need side-by-side batch-matched samples and larger n), then the most parsimonious explanation would be an ancestry-associated mutational hotspot at APOL1. Evidence of "fitness aligned mutagenesis"? Didn't see it. Mechanistic basis? Absent.
September 13, 2025 at 2:39 AM
Unlikely to me too. Assuming the diffs are real (need side-by-side batch-matched samples and larger n), then the most parsimonious explanation would be an ancestry-associated mutational hotspot at APOL1. Evidence of "fitness aligned mutagenesis"? Didn't see it. Mechanistic basis? Absent.