Patrick Aouad
@patrickaouad.bsky.social
Postdoc @Genentech 🇺🇸 - PhD/Postdoc @EPFL🇨🇭- M.S @AUB_Lebanon 🇱🇧 The right pre-clinical models for the right clinical questions. #BreastCancer #Metastasis
EMT and cancer: what clinicians should know doi.org/10.1038/s415...
EMT and cancer: what clinicians should know - Nature Reviews Clinical Oncology
Despite several decades of research that has revealed roles in the development and progression of many solid tumours, clinical translation of research targeting epithelial–mesenchymal transition (EMT)...
doi.org
July 23, 2025 at 6:03 PM
EMT and cancer: what clinicians should know doi.org/10.1038/s415...
ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer doi.org/10.1038/s430...
ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer - Nature Cancer
Liang et al. study the impact of ERα antagonist/degraders against different Esr1 mutations in murine models and find that inhibition of mutant ERα induces lineage plasticity, which is also observed in...
doi.org
April 28, 2025 at 8:31 PM
ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer doi.org/10.1038/s430...
The milk-producing structures, called Terminal Ductal Lobular Units (TDLUs), serve as the functional units of the human milk factory. Shown here is a section of #breast tissue stained with carmine alum, highlighting the epithelial structures of the mammary gland. Truly #fascinating! #Science
April 25, 2025 at 6:45 PM
The milk-producing structures, called Terminal Ductal Lobular Units (TDLUs), serve as the functional units of the human milk factory. Shown here is a section of #breast tissue stained with carmine alum, highlighting the epithelial structures of the mammary gland. Truly #fascinating! #Science
This week’s 3D reconstruction of the human #breast highlights the #myoepithelial cells- the contractile cells that help squeeze the milk-producing luminal cells to release milk and nourish offspring. Truly fascinating! #Science #Art
April 21, 2025 at 6:30 PM
This week’s 3D reconstruction of the human #breast highlights the #myoepithelial cells- the contractile cells that help squeeze the milk-producing luminal cells to release milk and nourish offspring. Truly fascinating! #Science #Art
Turning my Bluesky profile into a merge of #science 🔬 and #art 🎨: an exhibition featuring the beauty of the #breast through #microscopy. Starting with one of my favorites: 3D reconstruction of the human breast; Staining: Smooth muscle actin; Cells: Myoepithelial cells.
April 17, 2025 at 9:10 PM
Turning my Bluesky profile into a merge of #science 🔬 and #art 🎨: an exhibition featuring the beauty of the #breast through #microscopy. Starting with one of my favorites: 3D reconstruction of the human breast; Staining: Smooth muscle actin; Cells: Myoepithelial cells.
Our review on Dormancy and EMT received enough views to be a Top Viewed and Cited Article. Read about it here: onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle @wiley.com
Tumor dormancy: EMT beyond invasion and metastasis
More than two-thirds of cancer-related deaths are attributable to metastases. In some tumor types metastasis can occur up to 20 years after diagnosis and successful treatment of the primary tumor, a ...
onlinelibrary.wiley.com
April 16, 2025 at 4:58 PM
Our review on Dormancy and EMT received enough views to be a Top Viewed and Cited Article. Read about it here: onlinelibrary.wiley.com/doi/full/10.... #TopViewedArticle @wiley.com
Excited to attend this year’s GRS/C on mammary gland biology! Looking forward to connecting with experts in this inspiring field.
April 15, 2025 at 8:28 PM
Excited to attend this year’s GRS/C on mammary gland biology! Looking forward to connecting with experts in this inspiring field.