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ParasitesRule
@parasitesrule.org
Profile picture: Toxoplasma image taken by Omar Harb
Banner picture: Plasmodium from Volker Heussler
Reposted by ParasitesRule
Why do we care? Because very little information is available for proteins found in #parasites, despite parasites causing a third of the total global burden of human #disease (!!!) #MPM2025 @parasitesrule.org
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More about this problem is explained nicely here: www.sciencedirect.com/science/arti...
Exploiting structural biology in the fight against parasitic diseases
Despite spectacular advances in structural biology over the past half-century, only approximately 2% of the structures in the Protein Data Bank are fr…
www.sciencedirect.com
September 27, 2025 at 1:37 AM
Reposted by ParasitesRule
You can explore the full scRNAseq data on the same gene page: cryptodb.org/cryptodb/app...
September 23, 2025 at 5:34 PM
Reposted by ParasitesRule
How? By inhibiting the uptake of metabolically essential amino acids and disrupting the parasite's lifecycle.

You can learn more about some of their work here: pmc.ncbi.nlm.nih.gov/articles/PMC...

#Parasitology #MPMXXXVI #MPM2025
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Computational approaches for drug discovery against trypanosomatid-caused diseases
During three decades, only about 20 new drugs have been developed for malaria, tuberculosis and all neglected tropical diseases (NTDs). This critical situation was reached because NTDs represent only ...
pmc.ncbi.nlm.nih.gov
September 23, 2025 at 3:28 PM
Reposted by ParasitesRule
Learn more about some of their work here: pmc.ncbi.nlm.nih.gov/articles/PMC...

(Although ginger extract is used in this paper^. If anyone can point me towards publications of their studies using thyme extract please do!)

@parasitesrule.org #MPM2025 #Parasitology #MPM2025 #botany
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Efficacy of green synthesized silver nanoparticles via ginger rhizome extract against Leishmania major in vitro
Leishmaniasis is a major public health problem that causes by parasite of the genus Leishmania. The pentavalent antimonial compounds that used for treatment are not safe or effective enough. The aim o...
pmc.ncbi.nlm.nih.gov
September 23, 2025 at 3:57 PM