Parasite Lab
@parasitelab.bsky.social
Located on unceded Wurundjeri land at La Trobe University.
The Hedtke lab studies nematode parasites, their insect hosts, and bacterial endosymbionts to improve public health.
The Hedtke lab studies nematode parasites, their insect hosts, and bacterial endosymbionts to improve public health.
Mayfield, Sartorius, et al. 2025
When you find someone that has LF larvae in their blood ("microfilariaemia") then their household members are more likely to test positive for disease exposure.
Targeting households may enhance efficacy of annual treatments.
www.sciencedirect.com/science/arti...
When you find someone that has LF larvae in their blood ("microfilariaemia") then their household members are more likely to test positive for disease exposure.
Targeting households may enhance efficacy of annual treatments.
www.sciencedirect.com/science/arti...
Progression of lymphatic filariasis antigenaemia and microfilaraemia over 4.5 years in antigen-positive individuals, Samoa 2019-2023
The first round of triple-drug mass drug administration (MDA) for lymphatic filariasis (LF) in Samoa was in 2018. This study aims to i) examine progre…
www.sciencedirect.com
April 10, 2025 at 10:55 AM
Mayfield, Sartorius, et al. 2025
When you find someone that has LF larvae in their blood ("microfilariaemia") then their household members are more likely to test positive for disease exposure.
Targeting households may enhance efficacy of annual treatments.
www.sciencedirect.com/science/arti...
When you find someone that has LF larvae in their blood ("microfilariaemia") then their household members are more likely to test positive for disease exposure.
Targeting households may enhance efficacy of annual treatments.
www.sciencedirect.com/science/arti...
Reposted by Parasite Lab
Mayfield et al. 2025
Lymphatic filariasis causes chronic physical disability and social ostracization.
The disease persists despite drug distribution. Ongoing infections are a likely cause: we report 2 doses of 3 drugs isn't sufficient for some in Samoa.
www.sciencedirect.com/science/arti...
Lymphatic filariasis causes chronic physical disability and social ostracization.
The disease persists despite drug distribution. Ongoing infections are a likely cause: we report 2 doses of 3 drugs isn't sufficient for some in Samoa.
www.sciencedirect.com/science/arti...
Recurrence of microfilaraemia after triple-drug therapy for lymphatic filariasis in Samoa: Recrudescence or reinfection?
Contrasting evidence is emerging on the long-term effectiveness of triple-drug therapy for elimination of lymphatic filariasis (LF) in the Pacific reg…
www.sciencedirect.com
March 4, 2025 at 1:07 AM
Mayfield et al. 2025
Lymphatic filariasis causes chronic physical disability and social ostracization.
The disease persists despite drug distribution. Ongoing infections are a likely cause: we report 2 doses of 3 drugs isn't sufficient for some in Samoa.
www.sciencedirect.com/science/arti...
Lymphatic filariasis causes chronic physical disability and social ostracization.
The disease persists despite drug distribution. Ongoing infections are a likely cause: we report 2 doses of 3 drugs isn't sufficient for some in Samoa.
www.sciencedirect.com/science/arti...
Mayfield et al. 2025
Lymphatic filariasis causes chronic physical disability and social ostracization.
The disease persists despite drug distribution. Ongoing infections are a likely cause: we report 2 doses of 3 drugs isn't sufficient for some in Samoa.
www.sciencedirect.com/science/arti...
Lymphatic filariasis causes chronic physical disability and social ostracization.
The disease persists despite drug distribution. Ongoing infections are a likely cause: we report 2 doses of 3 drugs isn't sufficient for some in Samoa.
www.sciencedirect.com/science/arti...
Recurrence of microfilaraemia after triple-drug therapy for lymphatic filariasis in Samoa: Recrudescence or reinfection?
Contrasting evidence is emerging on the long-term effectiveness of triple-drug therapy for elimination of lymphatic filariasis (LF) in the Pacific reg…
www.sciencedirect.com
March 4, 2025 at 1:07 AM
Mayfield et al. 2025
Lymphatic filariasis causes chronic physical disability and social ostracization.
The disease persists despite drug distribution. Ongoing infections are a likely cause: we report 2 doses of 3 drugs isn't sufficient for some in Samoa.
www.sciencedirect.com/science/arti...
Lymphatic filariasis causes chronic physical disability and social ostracization.
The disease persists despite drug distribution. Ongoing infections are a likely cause: we report 2 doses of 3 drugs isn't sufficient for some in Samoa.
www.sciencedirect.com/science/arti...
Reposted by Parasite Lab
Thanks! In the meantime, you can see the preprint that's 98% identical to the eventual final copy:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Phylogenomic Insights into the Evolution and Origin of Nematoda
The phylum Nematoda represents one of the most cosmopolitan and abundant metazoan groups on Earth. In this study, we reconstructed the phylogenomic tree for phylum Nematoda. A total of 60 genomes, bel...
www.biorxiv.org
January 3, 2025 at 1:08 AM
Thanks! In the meantime, you can see the preprint that's 98% identical to the eventual final copy:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
It's really cool work!
January 3, 2025 at 1:02 AM
It's really cool work!
I just think of what could be done with all that money...
January 2, 2025 at 11:57 PM
I just think of what could be done with all that money...
Mayfield et al. 2024
Lymphatic filariasis is a parasite disease that is challenging the islands of the South Pacific. This is a baseline for future studies, combining evidence from different methods for testing disease after people received triple-drug therapy.
doi.org/10.3390/tropicalmed9120311
Lymphatic filariasis is a parasite disease that is challenging the islands of the South Pacific. This is a baseline for future studies, combining evidence from different methods for testing disease after people received triple-drug therapy.
doi.org/10.3390/tropicalmed9120311
December 26, 2024 at 12:23 AM
Mayfield et al. 2024
Lymphatic filariasis is a parasite disease that is challenging the islands of the South Pacific. This is a baseline for future studies, combining evidence from different methods for testing disease after people received triple-drug therapy.
doi.org/10.3390/tropicalmed9120311
Lymphatic filariasis is a parasite disease that is challenging the islands of the South Pacific. This is a baseline for future studies, combining evidence from different methods for testing disease after people received triple-drug therapy.
doi.org/10.3390/tropicalmed9120311
