Babis Pappas
@pappasgroup.bsky.social
Thank you very much @gomobel.bsky.social for highliting our work on @chemistryworld.com. Chiral acyl phosphates meet self-assembly..! Thanks also @claudiabonfio.bsky.social and @jeannecrassousiscr.bsky.social for the very nice comments about our work!!
Really cool stuff by @pappasgroup.bsky.social in @angewandtechemie.bsky.social – chiral chemical fuels drive molecules to self-assemble into different structures, depending on handedness 🧬 My latest for @chemistryworld.com 👉🏼 www.chemistryworld.com/news/chiral-... #ChemSky #RealTimeChem #Chemistry
Chiral chemical fuels trigger two very different supramolecular self-assemblies
Handedness of self-assembling peptides might explain the origins of homochirality in biological systems
www.chemistryworld.com
October 16, 2025 at 6:50 PM
Thank you very much @gomobel.bsky.social for highliting our work on @chemistryworld.com. Chiral acyl phosphates meet self-assembly..! Thanks also @claudiabonfio.bsky.social and @jeannecrassousiscr.bsky.social for the very nice comments about our work!!
Just out in @ChemRxiv
More than a leaving group!! We show how phosphate leaving groups can regulate reaction pathways and drive orthogonal amide bond formation. Well done Arti!
chemrxiv.org/engage/chemr...
More than a leaving group!! We show how phosphate leaving groups can regulate reaction pathways and drive orthogonal amide bond formation. Well done Arti!
chemrxiv.org/engage/chemr...
October 13, 2025 at 7:53 AM
Just out in @ChemRxiv
More than a leaving group!! We show how phosphate leaving groups can regulate reaction pathways and drive orthogonal amide bond formation. Well done Arti!
chemrxiv.org/engage/chemr...
More than a leaving group!! We show how phosphate leaving groups can regulate reaction pathways and drive orthogonal amide bond formation. Well done Arti!
chemrxiv.org/engage/chemr...
Thank you @ella-maru.bsky.social for the great design.
#SundayCover: Chemical system control itself with a simple handshake! 🤝
The @pappasgroup.bsky.social at @uni-freiburg.de developed a new feedback mechanism for controlling non-equilibrium systems based on chirality.
The @pappasgroup.bsky.social at @uni-freiburg.de developed a new feedback mechanism for controlling non-equilibrium systems based on chirality.
October 12, 2025 at 3:23 PM
Thank you @ella-maru.bsky.social for the great design.
Just out in @chemrxiv.org
Click or Acyl transfer? We show how amino acyl phosphates and peptide nucleophiles direct acyl transfer vs click chemistry, enabling temporal control in abiotic networks. Well done
@debjyoti8419.bsky.social
chemrxiv.org/engage/chemr...
Click or Acyl transfer? We show how amino acyl phosphates and peptide nucleophiles direct acyl transfer vs click chemistry, enabling temporal control in abiotic networks. Well done
@debjyoti8419.bsky.social
chemrxiv.org/engage/chemr...
September 18, 2025 at 5:09 AM
Just out in @chemrxiv.org
Click or Acyl transfer? We show how amino acyl phosphates and peptide nucleophiles direct acyl transfer vs click chemistry, enabling temporal control in abiotic networks. Well done
@debjyoti8419.bsky.social
chemrxiv.org/engage/chemr...
Click or Acyl transfer? We show how amino acyl phosphates and peptide nucleophiles direct acyl transfer vs click chemistry, enabling temporal control in abiotic networks. Well done
@debjyoti8419.bsky.social
chemrxiv.org/engage/chemr...
Happy to see the work from @lenardsaile.bsky.social
and Kun Dai highlighted #onTheCover of @angew_chem
(inside back cover). Thanks @EllaMaru
for the great design. Chiral aminoacyl phosphates!!!
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/10.1002/...
and Kun Dai highlighted #onTheCover of @angew_chem
(inside back cover). Thanks @EllaMaru
for the great design. Chiral aminoacyl phosphates!!!
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/10.1002/...
Inside Back Cover: Chirality Makes or Breaks Chemically Driven Self‐Assembly
In their Research Article (e202508481), Lenard Saile and Kun Dai et al. describe a feedback mechanism that controls non-equilibrium systems. Enantiomeric aminoacyl phosphates, depicted as left and ri...
onlinelibrary.wiley.com
September 3, 2025 at 5:46 AM
Happy to see the work from @lenardsaile.bsky.social
and Kun Dai highlighted #onTheCover of @angew_chem
(inside back cover). Thanks @EllaMaru
for the great design. Chiral aminoacyl phosphates!!!
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/10.1002/...
and Kun Dai highlighted #onTheCover of @angew_chem
(inside back cover). Thanks @EllaMaru
for the great design. Chiral aminoacyl phosphates!!!
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/10.1002/...
We are happy to share that our article on chirality-driven non-equilibrium assembly is published in @angewandtechemie.bsky.social !Congrats to Lenard and Kun for showing how left and right handed aminoacyl phosphates enable control over kinetics and pathways onlinelibrary.wiley.com/doi/10.1002/an…
August 1, 2025 at 7:00 AM
We are happy to share that our article on chirality-driven non-equilibrium assembly is published in @angewandtechemie.bsky.social !Congrats to Lenard and Kun for showing how left and right handed aminoacyl phosphates enable control over kinetics and pathways onlinelibrary.wiley.com/doi/10.1002/an…
We are very happy to share our recent publication in
@cp-chem.bsky.social on abiotic aminoacylation and side chain recognition through compartmentalization!
Congrats to Kun and Lenard, and everyone else involved in the work!
www.cell.com/chem/fulltex...
@cp-chem.bsky.social on abiotic aminoacylation and side chain recognition through compartmentalization!
Congrats to Kun and Lenard, and everyone else involved in the work!
www.cell.com/chem/fulltex...
Phase behavior and pathway-selective oligomerization driven by amino acid side-chain recognition
What basic ingredients enable amino acid side-chain recognition and assembly without
complex biological machinery? We show that even simple molecular sorters can organize
amino acids in space and time...
www.cell.com
May 13, 2025 at 5:06 AM
We are very happy to share our recent publication in
@cp-chem.bsky.social on abiotic aminoacylation and side chain recognition through compartmentalization!
Congrats to Kun and Lenard, and everyone else involved in the work!
www.cell.com/chem/fulltex...
@cp-chem.bsky.social on abiotic aminoacylation and side chain recognition through compartmentalization!
Congrats to Kun and Lenard, and everyone else involved in the work!
www.cell.com/chem/fulltex...
We are looking for a postdoctoral researcher to work on a project funded by the Boehringer Ingelheim Foundation on dynamic peptide self-assembly.
📄 Full position ad:
bit.ly/4jAIrmg
📅 Application deadline: May 31, 2025
#Postdoc #ChemistryJobs #SystemsChemistry #AcademicJobs #Freiburg #livMatS
📄 Full position ad:
bit.ly/4jAIrmg
📅 Application deadline: May 31, 2025
#Postdoc #ChemistryJobs #SystemsChemistry #AcademicJobs #Freiburg #livMatS
bit.ly
April 17, 2025 at 5:19 AM
We are looking for a postdoctoral researcher to work on a project funded by the Boehringer Ingelheim Foundation on dynamic peptide self-assembly.
📄 Full position ad:
bit.ly/4jAIrmg
📅 Application deadline: May 31, 2025
#Postdoc #ChemistryJobs #SystemsChemistry #AcademicJobs #Freiburg #livMatS
📄 Full position ad:
bit.ly/4jAIrmg
📅 Application deadline: May 31, 2025
#Postdoc #ChemistryJobs #SystemsChemistry #AcademicJobs #Freiburg #livMatS
Congratulations Mahesh for successfully defending your thesis! The first PhD student from the group. An amazing research journey ends here and we wish you all the best for your future research adventures!!
February 7, 2025 at 11:01 AM
Congratulations Mahesh for successfully defending your thesis! The first PhD student from the group. An amazing research journey ends here and we wish you all the best for your future research adventures!!
Happy for our published article in @NatureComms
showing the departure from randomness in peptide bond formation through aminoacyl phosphate esters. Congratulations to Arti and everyone involved.@livMatS_UniFR
@UniFreiburg
@FreiburgChem
@FitFreiburg
nature.com/articles/s41...
showing the departure from randomness in peptide bond formation through aminoacyl phosphate esters. Congratulations to Arti and everyone involved.@livMatS_UniFR
@UniFreiburg
@FreiburgChem
@FitFreiburg
nature.com/articles/s41...
Selective peptide bond formation via side chain reactivity and self-assembly of abiotic phosphates - Nature Communications
In biological processes, peptide bonds are formed via reactive phosphate-containing intermediates, facilitated by compartmentalized environments. Here, the authors use aminoacyl phosphate esters that ...
nature.com
February 4, 2025 at 6:44 AM
Happy for our published article in @NatureComms
showing the departure from randomness in peptide bond formation through aminoacyl phosphate esters. Congratulations to Arti and everyone involved.@livMatS_UniFR
@UniFreiburg
@FreiburgChem
@FitFreiburg
nature.com/articles/s41...
showing the departure from randomness in peptide bond formation through aminoacyl phosphate esters. Congratulations to Arti and everyone involved.@livMatS_UniFR
@UniFreiburg
@FreiburgChem
@FitFreiburg
nature.com/articles/s41...
We have a PhD position on reaction networks driven by aminoacyl phosphate esters funded from @ercresearch.bsky.social at @uni-freiburg.de.
Deadline for application is 20/03/25. More information can be found here: static1.squarespace.com/static/5fc39...
Deadline for application is 20/03/25. More information can be found here: static1.squarespace.com/static/5fc39...
February 3, 2025 at 6:44 AM
We have a PhD position on reaction networks driven by aminoacyl phosphate esters funded from @ercresearch.bsky.social at @uni-freiburg.de.
Deadline for application is 20/03/25. More information can be found here: static1.squarespace.com/static/5fc39...
Deadline for application is 20/03/25. More information can be found here: static1.squarespace.com/static/5fc39...