Papalopulu Lab
papalopululab.bsky.social
Papalopulu Lab
@papalopululab.bsky.social
Interested in how changes in gene expression dynamics underlie cell state transitions in development and cancer. Our team is led by Prof Nancy Papalopulu and we are based at the University of Manchester.
With the deadline fast approaching don't miss these opportunities to study at Manchester!
Are you enthusiastic about stem cell biology and developmental biology and looking to start a PhD in 2026? Funded opportunites now available. Contact for more infomation. Links below! @lovegrovelab.bsky.social @veronicabiga.bsky.social @manchester.ac.uk @ukri.org
November 4, 2025 at 11:05 AM
Two exciting PhD opportunities at the University of Manchester! Apply before Nov 8th!
Are you enthusiastic about stem cell biology and developmental biology and looking to start a PhD in 2026? Funded opportunites now available. Contact for more infomation. Links below! @lovegrovelab.bsky.social @veronicabiga.bsky.social @manchester.ac.uk @ukri.org
October 21, 2025 at 8:15 AM
Reposted by Papalopulu Lab
ICYMI, the recordings of our #DevPres webinar on gene regulation are now available.
Check out the talks from @dev-journal.bsky.social PI fellows Anzy Miller @anzymiller.bsky.social and Marlies Oomen @marliesoomen.bsky.social.
thenode.biologists.com/catch-up-on-...
#devbio 🎥
Catch up on Development presents… webinar on gene regulation - the Node
Catch up on the Development presents... gene regulation webinar, featuring talks from two of Development's PI fellows.
thenode.biologists.com
September 12, 2025 at 10:49 AM
Check out the Perspective piece by our colleague @anzymiller.bsky.social and other fellows on the Pathway to Independence programme!
September 30, 2025 at 4:26 PM
This exciting study led by @anzymiller.bsky.social is now published! NGN3 oscillations control the timing of differentiation during pancreas development through a fold-change sensitive gene regulatory motif. Congratulations to all authors!
I’m really pleased to share that our paper is out in Developmental Cell! NGN3 oscillates in the developing pancreas and controls the timing of cell differentiation via an incoherent feed-forward motif. For more details check out the comments below and DOI: 10.1016/j.devcel.2025.06.004
July 4, 2025 at 4:00 PM
A must read!
Our latest "Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data"

A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making

Applied to ventral neural tube development

www.biorxiv.org/content/10.1...
Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data
Building a mechanistic understanding of cell fate decisions remains a fundamental goal of developmental biology, with implications for stem cell therapies, regenerative medicine and understanding dise...
www.biorxiv.org
May 30, 2025 at 10:38 AM
In our latest study by @veronicabiga.bsky.social, we explore how the “Oscillatory Co-expression of HES1 and HES5 Enables a Hybrid State in a Bistable Transcription Factor Regulatory Motif”:
www.biorxiv.org/content/10.1...
Oscillatory Co-expression of HES1 and HES5 Enables a Hybrid State in a Bistable Transcription Factor Regulatory Motif
Many cell fate decisions in the developing neural tube are directed by cross-repressive transcription factor (TF) motifs that generate bistability, enforcing expression of one dominant TF. However, ev...
www.biorxiv.org
May 29, 2025 at 3:52 PM
We're very excited to announce that our colleague @anzymiller.bsky.social is about to begin her @dev-journal.bsky.social Pathway to Independence journey! This will provide mentoring and support to emerging researchers in developmental biology and stem cells . journals.biologists.com/dev/pages/pi...
PI programme | Development | The Company of Biologists
PI programme | Development | The Company of Biologists Development's Pathway to Independence programme Development is excited to announce our call for our Pathway to Independence program...
journals.biologists.com
May 7, 2025 at 9:33 AM
Reposted by Papalopulu Lab
We are also highlighting John Gurdon, 2012 Nobel laureate in Physiology or Medicine and former Chair of the Board of Directors at @biologists.bsky.social, as an extraordinary biologist. #100biologists
April 10, 2025 at 12:13 PM
Reposted by Papalopulu Lab
We're excited to host two fantastic speakers at our next online @physicsoflifeuk.bsky.social ECR Seminar on Tuesday 15 April, 2–3 PM BST:
Tisma Milos and Thomas McLean
chaired by @veronicabiga.bsky.social

Please register below for the Zoom link:
lnkd.in/dSynrAe8
April 10, 2025 at 10:44 AM
Reposted by Papalopulu Lab
We are highlighting Kate Storey, who served as a Director at @biologists.bsky.social from 2007 to 2022 and co-founded the Company’s Workshop programme, as an extraordinary biologist. #100biologists
April 8, 2025 at 12:08 PM
We just joined Bluesky and we're hoping to connect with fellow scientists interested in quantitative and developmental biology! Follow us for future updates! Logo credit goes to @golgigraphics.bsky.social
April 8, 2025 at 12:11 PM