Ozanne Lab
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ozannelab.bsky.social
Ozanne Lab
@ozannelab.bsky.social
290 followers 96 following 4 posts
We are Sue Ozanne's lab in the IMS at the University of Cambridge. We study how the early life environment impacts on offspring cardio-metabolic health.
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Reposted by Ozanne Lab
mrcepid.bsky.social
There are many reasons pregnant women can develop gestational diabetes &
researchers from @ims-mrl.bsky.social are investigating interventions that can be used to mitigate the condition.

Dr @dftwinn.bsky.social
Dr Adriana Paz Cordona Casanova
Dr Lais Vales Mennetti

Listen - buff.ly/7Kymdzy
November 12, 2025 at 11:30 AM
Reposted by Ozanne Lab
ims-mrl.bsky.social
An excellent podcast from the @ozannelab.bsky.social at @ims-mrl.bsky.social in the lead up to #WorldDiabetesDay 2025
mrcepid.bsky.social MRC Epidemiology Unit @mrcepid.bsky.social · 15d
There are many reasons pregnant women can develop gestational diabetes &
researchers from @ims-mrl.bsky.social are investigating interventions that can be used to mitigate the condition.

Dr @dftwinn.bsky.social
Dr Adriana Paz Cordona Casanova
Dr Lais Vales Mennetti

Listen - buff.ly/7Kymdzy
November 12, 2025 at 11:38 AM
Reposted by Ozanne Lab
diabetologiajnl.bsky.social
Up front & free to read in our Nov issue #editorspicks: The utility of early gestational OGTT and biomarkers for the development of gestational diabetes mellitus: an international prospective multicentre cohort study link.springer.com/article/10.1...
The utility of early gestational OGTT and biomarkers for the development of gestational diabetes mellitus: an international prospective multicentre cohort study - Diabetologia
Aims/hypothesis There is no clear consensus regarding accurate risk stratification in early pregnancy for later developing gestational diabetes mellitus (GDM). Therefore, this study aims to evaluate t...
link.springer.com
November 5, 2025 at 8:26 AM
Reposted by Ozanne Lab
fabiolasuano.bsky.social
www.bmj.com/content/389/...
@ozannelab.bsky.social @ims-mrl.bsky.social
Challenges with developing nutritional recommendations to improve pregnancy outcomes
Susan Ozanne and colleagues argue that strategies are urgently needed to translate knowledge about how maternal nutrition affects children’s long term health into improved population health outcomes ...
www.bmj.com
September 28, 2025 at 10:43 AM
Reposted by Ozanne Lab
rebeccadumbell.bsky.social
This week @helferlab.bsky.social and I had a great and productive day visiting @mrcharwell.bsky.social to help get set up for my @acmedsci.bsky.social funded animal study. Really excited to be moving forward! 🐭🧠🍔🔬
Gisela Maria Rebecca and Tania in a selfie in front of the signage for the Mary Lyon Centre at MRC Harwell
September 17, 2025 at 12:48 PM
Reposted by Ozanne Lab
gilesyeo.bsky.social
I’ve been hosting the 7th International Melanocortin Meeting here in Cambridge with my co-organisers Roger Cone, Kate Ellacott @neuroendo.bsky.social and Anne White. Spectacular science! Here we are at the conference dinner! #obesityisnotachoice
September 17, 2025 at 3:39 PM
Reposted by Ozanne Lab
neuroendo.bsky.social
The 7th International Melanocortin meeting was full of energy, science & connections old & new. I will miss the excuse to regularly catch up with my fellow organisers Giles @gilesyeo.bsky.social, Anne @annewhite-uom.bsky.social, & Roger Cone. Thanks to Bioscientifica @socendocrinology.bsky.social
Organisers of 7th International Melanocortin Meeting Kate Ellacott, Giles Yeo, Anne White and Roger Cone
September 17, 2025 at 4:24 PM
Reposted by Ozanne Lab
diabetologiajnl.bsky.social
In our new special issue: Prevention of type 2 diabetes in migrant populations from low- and middle-income countries living in high-income countries link.springer.com/article/10.1.... See the full collection here diabetologia-journal.org/collections/...
Prevention of type 2 diabetes in migrant populations from low- and middle-income countries living in high-income countries - Diabetologia
The rising prevalence of type 2 diabetes among migrant populations from low- and middle-income countries (LMICs) living in high-income countries (HICs) presents a significant public health challenge. ...
link.springer.com
September 18, 2025 at 8:15 AM
Reposted by Ozanne Lab
jimjohnsonsci.bsky.social
Hey friends and colleagues ! Vancouver Coastal Health Research Institute - VCHRI is now on Bluesky, give them a follow @vchresearch.bsky.social
Vancouver Coastal Health Research Institute (@vchresearch.bsky.social)
Vancouver Coastal Health Research Institute — Leading innovative research with health impact in Canada. vchri.ca
vchresearch.bsky.social
September 14, 2025 at 9:49 AM
Reposted by Ozanne Lab
charlyguardia.bsky.social
Here are the curated lists of pubs in the #PlacentalCellBio
@biomednews.bsky.social report from the last two weeks!

biomed.news/bims-placeb/...
biomed.news/bims-placeb/...

My personal choice: this resource from the Zernicka-Goetz's lab! pubmed.ncbi.nlm.nih.gov/40882624/

Enjoy!
Efficient stem cell-derived mouse embryo models for environmental studies - PubMed
Blastoids are stem cell-derived structures that mimic natural blastocysts by incorporating all three lineages: trophectoderm, epiblast, and primitive endoderm. However, current methods often yield inc...
pubmed.ncbi.nlm.nih.gov
September 14, 2025 at 3:23 PM
Reposted by Ozanne Lab
ims-mrl.bsky.social
Sharing for our colleagues at @edinburgh-uni.bsky.social who are carrying out a survey on weight loss drugs and pregnancy.
Please help us learn more.
Take the survey
👇👇👇👇 app.onlinesurveys.jisc.ac.uk/s/edinburgh/...
August 19, 2025 at 9:42 AM
Reposted by Ozanne Lab
isandovici.bsky.social
Very cool paper connecting nutrition, epigenetics and developmental biology. rdcu.be/eptl7
Maternal iron deficiency causes male-to-female sex reversal in mouse embryos
Nature - Iron-deficient conditions in pregnant mice can cause XY mouse embryos to develop female rather than male genitalia, revealing that iron metabolism has a role in determining male sex in mice.
rdcu.be
June 4, 2025 at 5:57 PM
Reposted by Ozanne Lab
bradleyjamieson.bsky.social
🎉 Thrilled to share my postdoc work, with our preprint out now on BiorXiv here: www.biorxiv.org/content/10.1...

We investigated how the juvenile brain develops the ability to carry out care behaviours towards neonates by an exciting and surprising switch in neural activity and behaviour
www.biorxiv.org
June 16, 2025 at 8:17 AM
Reposted by Ozanne Lab
bsneuroendo.bsky.social
🏆 CONGRATULATIONS to Jo Lewis, 2025 winner of the Michael Harbuz Prize!

Jo will speak at #BSNBradford2025 on Glucose-dependent insulinotropic polypeptide regulates food intake and body weight via the area postrema in mice.

Register: bsnbradford2025.oa-e...
July 21, 2025 at 12:07 PM
Reposted by Ozanne Lab
cam-repro.bsky.social
“Our children’s lifelong health starts in the first 1,000 days - from conception to age two"

@acmedsci.bsky.social report, co-chaired by our very own co-chair Susan Ozanne @ozannelab.bsky.social underscores that habits and environments established early are hard to change later

Read more 👇
acmedsci.bsky.social Academy of Medical Sciences @acmedsci.bsky.social · Jul 2
🚨 Childhood obesity is rising at alarming rates around the world

Our latest report, with Italy’s Accademia Nazionale dei Lincei, calls for early intervention to ensure healthier futures for all children 🌱

Read the report: bit.ly/46qy7tN

And see our key takeaways 🧵
Child’s weight for life shaped by first 1,000 days, report health experts
bit.ly
July 3, 2025 at 1:05 PM
Reposted by Ozanne Lab
neuroendolille.bsky.social
Huge congratulations to Serge Luquet on receiving the Silver Medal from @CNRS! So well deserved 👏🏻
www.insb.cnrs.fr/fr/personne/...
Serge Luquet
www.insb.cnrs.fr
July 2, 2025 at 11:52 AM
Reposted by Ozanne Lab
mrcepid.bsky.social
The BioRepository's Cambridge-based Nordic ULT Freezer System offers:

100% backup for sample security
24/7 monitoring & telemetry
Energy savings & reduced carbon footprint

Contact us to find out how we can support your research - BioRepManager@mrc-epid.cam.ac.uk
July 2, 2025 at 3:53 PM
Reposted by Ozanne Lab
acmedsci.bsky.social
Co-published with Italy’s Accademia Nazionale dei Lincei, this report shows that success comes from addressing the systems and environments shaping children’s health, not just individual behaviours.

🔗 Read the report: bit.ly/46qy7tN
Professor Paolo Vineis next to a quote that reads: "This collaboration between the UK and Italy has revealed that childhood obesity transcends borders – it is a shared challenge requiring coordinated action. The evidence demonstrates that success comes from addressing the systems and environments shaping children’s health, not just individual behaviours."
July 2, 2025 at 8:45 AM
Reposted by Ozanne Lab
acmedsci.bsky.social
This analysis comes ahead of the NHS 10-Year Health Plan to address health inequalities and echoes the Council for Science and Technology’s letter - co-chaired by our President Prof Andrew Morris CBE FRSE PMedSci - for bold leadership and cross-govt action to prioritise prevention.
July 2, 2025 at 8:45 AM
Reposted by Ozanne Lab
acmedsci.bsky.social
Key evidence includes:

👶 The first 1,000 days of life shape lifelong health
📉 Obesity rates are 2x higher in deprived areas
🏘️ Public health interventions beat individual fixes

Our Vice President (Clinical), Prof @rosalindsmyth.bsky.social CBE FMedSci, shares the importance of early action 👇
Professor Rosalind Smyth CBE FMedSci next to a quote that reads: "When we address health inequalities in the earliest years, we’re not just improving individual outcomes – we're building the foundations for a healthier, more productive society. The evidence reinforces that prevention, which requires a cross-sectoral approach, must be coordinated across all government departments."
July 2, 2025 at 8:45 AM
Reposted by Ozanne Lab
acmedsci.bsky.social
🚨 Childhood obesity is rising at alarming rates around the world

Our latest report, with Italy’s Accademia Nazionale dei Lincei, calls for early intervention to ensure healthier futures for all children 🌱

Read the report: bit.ly/46qy7tN

And see our key takeaways 🧵
Child’s weight for life shaped by first 1,000 days, report health experts
bit.ly
July 2, 2025 at 8:45 AM
Reposted by Ozanne Lab
acmedsci.bsky.social
The report calls for urgent action to:

🤰 Prioritise support during pregnancy
🍴 Ensure robust regulation of the food industry
🤝 Coordinate across govt departments i.e. food, education, urban planning and transport
Professor Susan Ozanne FMedSci next to a quote that reads: "The first 1,000 days, including time in the womb, represent an important window of opportunity to set children on a healthy trajectory for life. This isn’t about individual willpower or blaming and shaming – it's about creating an environment for parents, carers and their children that supports healthy development from the very beginning."
July 2, 2025 at 8:45 AM
Reposted by Ozanne Lab
jmschoonejans.bsky.social
This highlights the need for long-term cardiovascular follow up in offspring (of both sexes!) from human metformin-treated pregnancies to inform decisions about its use in pregnancy - a tricky question that requires balancing mum and baby's health 👩‍🍼
June 23, 2025 at 3:14 PM
Reposted by Ozanne Lab
jmschoonejans.bsky.social
Offspring of obese mice had hypertension and diastolic dysfunction by 12mo. Maternal #metformin worsened the phenotype and introduced sex-dependent CV alterations in both male (cardiac stiffening, vascular dysfunction) & female (obesity-induced hypertension) offspring.
June 23, 2025 at 3:14 PM
Reposted by Ozanne Lab
jmschoonejans.bsky.social
Our new paper showing sex-specific adverse #cardiovascular outcomes of prenatal #metformin exposure in a mouse model of diet-induced glucose intolerance is out now in @jphysiol.bsky.social ! 🐁❤️ ♂️♀ Find it here shorturl.at/VKqjD (in collab with @ozannelab.bsky.social & Giussani labs) #DOHaD
June 23, 2025 at 3:14 PM