Ousmane H. Cisse
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ousmanecis.bsky.social
Ousmane H. Cisse
@ousmanecis.bsky.social
130 followers 180 following 8 posts
Microbiology | fungal pathogens focus pneumocystis | posts don’t represent employer

https://scholar.google.com/citations?user=sjUY-OYAAAAJ&hl=en
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ousmanecis.bsky.social
Ousmane H. Cisse @ousmanecis.bsky.social · Apr 23
journals.asm.org/doi/abs/10.1...
Retracing the evolution of Pneumocystis species, with a focus on the human pathogen Pneumocystis jirovecii | Microbiology and Molecular Biology Reviews
SUMMARYEvery human being is presumed to be infected by the fungus Pneumocystis jirovecii at least once in his or her lifetime. This fungus belongs to a large group of species that appear to exclusivel...
journals.asm.org
Reposted by Ousmane H. Cisse
lancetmicrobe.bsky.social
Our September issue is now online:

www.thelancet.com/journals/lan...

Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #SARS-CoV-2 #HIV #Pneumocystis #tuberculosis #TB #gonorrhoea #Citrobacter #AMR #Salmonella

#IDSky #ClinMicro #OA
Cover of The Lancet Microbe's September issue with a "Light micrograph of a lung sample from an AIDS patient showing cysts of Pneumocystis [jirovecii]".
September 9, 2025 at 8:35 AM
Reposted by Ousmane H. Cisse
biorxivpreprint.bsky.social
Homology-mediated transformation of frog-killing fungus Batrachochytrium dendrobatidis illuminates chytrid development and pathogenesis https://www.biorxiv.org/content/10.1101/2025.08.29.673073v1
August 31, 2025 at 8:30 PM
ousmanecis.bsky.social
Interesting perspective - few more to add from fungal pathogens perspective. Also pathogens and hosts often operate on different molecular clocks. journals.plos.org/plosbiology/...
Why are there so few pathogens? Ecology and evolution in pathogen emergence
Why are there so few pathogens, and what determines their emergence? This Perspective argues that ecological and evolutionary forces (host availability, geographic exposure and microbial innovation) w...
journals.plos.org
August 31, 2025 at 9:33 PM
Reposted by Ousmane H. Cisse
femsjournals.bsky.social
In this review, @liangma20854 et al. discuss #Pneumocystis epidemiology, coinfection, cross-infection, and coevolution aspects. #pneumonia
buff.ly/3X0yKSR
#FEMSMicrobiolRev
June 28, 2025 at 8:00 AM
ousmanecis.bsky.social
www.biorxiv.org/content/10.1... - really cool study from U. Cincinnati
Extracellular Vesicle-Mediated Delivery of Genetic Material for Transformation and CRISPR/Cas9-based Gene Editing in Pneumocystis murina
Pneumocystis species are obligate fungal pathogens that cause severe pneumonia, particularly in immunocompromised individuals. The absence of robust genetic manipulation tools has impeded our mechanis...
www.biorxiv.org
July 2, 2025 at 1:44 AM
Reposted by Ousmane H. Cisse
hyphaltip.bsky.social
share.transistor.fm/s/ee922716 - nice interview with Joe Heitman on Fungi
Cosmic Radio Interview with Dr. Joseph Heitman: Professor and Chair of Molecular Genetics and Professor in Medicine at Duke University and CIFAR's Co-Director for the Fungal Kingdom: Threats & Opportu...
Join me on Cosmic Radio as we speak with Dr. Joseph Heitman. Dr. Heitman is a professor and Chair of Molecular Biology and Professor in Medicine at Duke University and CIFAR's Co-Director for the "Fun...
share.transistor.fm
May 10, 2025 at 7:30 PM
ousmanecis.bsky.social
journals.asm.org/doi/abs/10.1...
Retracing the evolution of Pneumocystis species, with a focus on the human pathogen Pneumocystis jirovecii | Microbiology and Molecular Biology Reviews
SUMMARYEvery human being is presumed to be infected by the fungus Pneumocystis jirovecii at least once in his or her lifetime. This fungus belongs to a large group of species that appear to exclusivel...
journals.asm.org
April 23, 2025 at 10:40 AM
ousmanecis.bsky.social
www.biorxiv.org/content/10.1...
Single-Cell RNA Sequencing Defines Developmental Progression and Reproductive Transitions of Pneumocystis carinii
Pneumocystis species are host-obligate fungal pathogens that cause severe pneumonia in immunocompromised individuals. Despite their clinical importance, their life cycle remains poorly understood, in ...
www.biorxiv.org
April 23, 2025 at 10:06 AM
ousmanecis.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...
CRISPR-mediated detection of Pneumocystis transcripts in bronchoalveolar, oropharyngeal, and serum specimens for Pneumocystis pneumonia diagnosis
Pneumocystis jirovecii pneumonia (PCP) is a leading cause of fungal pneumonia, but its diagnosis primarily relies on invasive bronchoalveolar lavage (BAL) specimens that are difficult to obtain. Oroph...
pmc.ncbi.nlm.nih.gov
April 19, 2025 at 1:08 PM
ousmanecis.bsky.social
Interesting hypothesis worth exploring further www.nature.com/articles/s42...
Pneumocystis jirovecii is a potential pivotal ecological driver contributing to shifts in microbial equilibrium during the early-life lower airway microbiome assembly - Communications Biology
Early-life lung microbiota is dynamic, with major shifts at 3–4 months. Transient microbes dominate, but some persist, influencing lung health. Pneumocystis jirovecii may be a key driver of microbial ...
www.nature.com
April 19, 2025 at 1:08 PM
ousmanecis.bsky.social
journals.asm.org/doi/10.1128/...
Selective expression of Pneumocystis antigens in different patients during a suspected outbreak of Pneumocystis pneumonia | mBio
The fungus Pneumocystis causes severe pneumonia in patients with weakened immune systems. It possesses a genetic system to vary the antigens at the surface of its cells that are presented to the immun...
journals.asm.org
April 19, 2025 at 1:03 PM
Reposted by Ousmane H. Cisse
therad-lab.bsky.social
Nice article in The Telegraph today about importance of fungal infections and the need for more research. Lots of quotes from UK researchers!
www.telegraph.co.uk/global-healt...
Fungal infections are ‘taking over the world’. Can they be stopped?
As a landmark WHO report warns of a lack of treatments and diagnosis, we investigate a threat that now kills twice as many people as TB
www.telegraph.co.uk
April 7, 2025 at 10:04 AM
Reposted by Ousmane H. Cisse
germhuntermd.bsky.social
Comparative efficacy and safety of treatment regimens for Pneumocystis jirovecii pneumonia in people living with HIV – A systematic review and network meta-analysis of randomized controlled trials

Hatzl et al

TLDR: “no clear best choice”

www.clinicalmicrobiologyandinfection.com/article/S119...
Visual abstract
December 27, 2024 at 1:16 PM