Ottilie Le Doeuff
ottilield.bsky.social
Ottilie Le Doeuff
@ottilield.bsky.social
PhD candidate in oncogenic virology and DNA damage repair.
Lab Amélie Fradet-Turcotte - Québec
Reposted by Ottilie Le Doeuff
I am very excited to share the newest paper of the lab, a huge amount of work led by our talented PhD student Maxime Galloy, in close collaboration with Andréanne Blondeau, our dedicated research assistant for 10 years! 🙌

www.cell.com/molecular-ce...
Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress
Using biochemical assays and a mutant disrupting RNF168-dependent ubiquitination of the histone variant macroH2A1.2, Galloy et al. identified an unexpected role for histone mH2A1.2 ubiquitination in p...
www.cell.com
August 13, 2025 at 3:20 PM