OrianRousseauLab
@orianrousseaulab.bsky.social
Our Lab is studying tumor growth and metastasis. We focus on gastro-intestinal cancers but are also highly interested in various types of leukaemia. We make extensive use of organoids. Homepage: https://fms.ibcs.kit.edu/orian-rousseau.php
Thanks to Matt Hepworth for the kind invitation to give a talk as part of the Manchester Immunology Group Seminar Series!
Great to visit the Lydia Becker Institute of Immunology and Inflammation! Thanks to L. Roberts, J. Allen and all other PIs
#CD44 #Immunology #KIT#Manchester
Great to visit the Lydia Becker Institute of Immunology and Inflammation! Thanks to L. Roberts, J. Allen and all other PIs
#CD44 #Immunology #KIT#Manchester
October 10, 2025 at 9:46 AM
Thanks to Matt Hepworth for the kind invitation to give a talk as part of the Manchester Immunology Group Seminar Series!
Great to visit the Lydia Becker Institute of Immunology and Inflammation! Thanks to L. Roberts, J. Allen and all other PIs
#CD44 #Immunology #KIT#Manchester
Great to visit the Lydia Becker Institute of Immunology and Inflammation! Thanks to L. Roberts, J. Allen and all other PIs
#CD44 #Immunology #KIT#Manchester
CD44 in Group 1 Innate Lymphoid Cells Impacts the Development and Progression of Steatohepatitis - Bourinet - 2025 - Liver International - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
Congratulations to the groups of P. Gual and C. Luci. Thanks for involving us in this work
Congratulations to the groups of P. Gual and C. Luci. Thanks for involving us in this work
CD44 in Group 1 Innate Lymphoid Cells Impacts the Development and Progression of Steatohepatitis
Background and Aims Innate lymphoid cells (ILCs) play pivotal roles in inflammation and fibrosis, which are key features of chronic liver diseases. The contribution of group 1 ILCs, including natura...
onlinelibrary.wiley.com
September 1, 2025 at 8:47 AM
CD44 in Group 1 Innate Lymphoid Cells Impacts the Development and Progression of Steatohepatitis - Bourinet - 2025 - Liver International - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
Congratulations to the groups of P. Gual and C. Luci. Thanks for involving us in this work
Congratulations to the groups of P. Gual and C. Luci. Thanks for involving us in this work
Here is our new paper on pancreatic cancer metastasis. Using a mouse model, we show that removing Cd44/Cd44v6 in bone marrow–derived cells disrupts the metastatic niche and, as a result, reduces pancreatic cancer metastasis #CD44 #pancreatic cancer #metastatic niche
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reprogramming Immunosuppressive Bone Marrow Derived Cells via CD44 Targeting Impacts Pancreatic Cancer Metastasis
Pancreatic ductal adenocarcinoma (PDAC) is characterized by early dissemination and an aggressive metastatic course. In order to establish in the liver, metastatic cells require a metastatic niche pro...
www.biorxiv.org
August 18, 2025 at 1:31 PM
Here is our new paper on pancreatic cancer metastasis. Using a mouse model, we show that removing Cd44/Cd44v6 in bone marrow–derived cells disrupts the metastatic niche and, as a result, reduces pancreatic cancer metastasis #CD44 #pancreatic cancer #metastatic niche
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Congratulations to my student Lisa-Marie Mehner who obtained "summa cum laude" (with highest honor) for her PhD on the role of CD44+ bone marrow derived cells in the pancreatic cancer metastatic niche". Well deserved Frau Dr Mehner!Karlsruhe Institute of Technology (KIT) #pancreatic cancer #CD44
July 19, 2025 at 7:46 AM
Congratulations to my student Lisa-Marie Mehner who obtained "summa cum laude" (with highest honor) for her PhD on the role of CD44+ bone marrow derived cells in the pancreatic cancer metastatic niche". Well deserved Frau Dr Mehner!Karlsruhe Institute of Technology (KIT) #pancreatic cancer #CD44
G. Laverny and V. Orian-Rousseau share with you their project funded by the canceropole EST. This is the first step of the growing collaboration between the GenomEast platform (IGBMC) and the Organoid Research Centre (KIT, IBCS-FMS) hashtag#KIT hashtag#UNISTRA hashtag#igbmc hashtag#organoids
June 23, 2025 at 2:57 PM
G. Laverny and V. Orian-Rousseau share with you their project funded by the canceropole EST. This is the first step of the growing collaboration between the GenomEast platform (IGBMC) and the Organoid Research Centre (KIT, IBCS-FMS) hashtag#KIT hashtag#UNISTRA hashtag#igbmc hashtag#organoids
Fruitful meeting at Mont St Odile, France: PIs from UNISTRA, KIT, Uni Freiburg, Uni-clinic Freiburg and Basel University forming an immunology- oncology network in the EUCOR region. @kit.edu @unistra.fr @eucor-uni.org @uni-freiburg.de
@unibas.ch
@unibas.ch
June 4, 2025 at 7:59 PM
Fruitful meeting at Mont St Odile, France: PIs from UNISTRA, KIT, Uni Freiburg, Uni-clinic Freiburg and Basel University forming an immunology- oncology network in the EUCOR region. @kit.edu @unistra.fr @eucor-uni.org @uni-freiburg.de
@unibas.ch
@unibas.ch
Karlsruhe Institute of Technology (KIT): Scientific Review of the Helmholtz Research Field Information: Group Schepers, Le Noble and Orian-Rousseau at the inauguration of our new self-driving Bio.Mat lab where we will standardize organoid engineering @kit.edu #organoids
May 28, 2025 at 8:44 AM
Karlsruhe Institute of Technology (KIT): Scientific Review of the Helmholtz Research Field Information: Group Schepers, Le Noble and Orian-Rousseau at the inauguration of our new self-driving Bio.Mat lab where we will standardize organoid engineering @kit.edu #organoids
Very grateful to Dr Julie Martin, Dr Sven Treffert and Nagwa Ibrahim for representing our group at Campus Day (KIT) and for presenting our work on pancreatic and colorectal cancer!
Such a great team!
Such a great team!
May 17, 2025 at 3:16 PM
Very grateful to Dr Julie Martin, Dr Sven Treffert and Nagwa Ibrahim for representing our group at Campus Day (KIT) and for presenting our work on pancreatic and colorectal cancer!
Such a great team!
Such a great team!
So proud to see my daughter Claire Rousseau giving a talk on her work on the Herpes Virus at the 9th European Congress of Virology 2025, Cavtat, Croatia
May 1, 2025 at 3:25 PM
So proud to see my daughter Claire Rousseau giving a talk on her work on the Herpes Virus at the 9th European Congress of Virology 2025, Cavtat, Croatia
Check out this paper from the group of Philippe Gual, INSERM U1065, Nice, France. Our Cd44 floxed mice were used in this study on alcohol-related liver diseases (ALD). Many thanks to Philippe Gual for a very successful collaboration
January 17, 2025 at 4:10 PM
Check out this paper from the group of Philippe Gual, INSERM U1065, Nice, France. Our Cd44 floxed mice were used in this study on alcohol-related liver diseases (ALD). Many thanks to Philippe Gual for a very successful collaboration
Congratulations to Dr Sven Treffert for his excellent PhD defence on CD44 as a key player in Radiotherapy resistance, fibrosis and immune escape in pancreatic cancer. We think the Wilhelm Sander-Stiftung for the support @sander stiftung
December 12, 2024 at 7:14 PM
Congratulations to Dr Sven Treffert for his excellent PhD defence on CD44 as a key player in Radiotherapy resistance, fibrosis and immune escape in pancreatic cancer. We think the Wilhelm Sander-Stiftung for the support @sander stiftung
