Plot twist: Your data probably violates metric axioms.
Your tools don't check. They just compute nonsense.

Topolow bridges non-metric data to valid analysis
-Handles up to 95% sparsity
-Higher accuracy than MDS

install.packages("topolow")
Euclidify(dissimilarities)
doi.org/10.48550/arX...
#RStats

The way we name our #manuscript revisions on @overleaf.com

We tested Topolow on the classic H3N2 influenza data. Our map is similar to the lab-validated map AND our antigenic velocity vectors automatically identify cluster transitions previously found with reverse-genetics.
See analyses in our Bioinformatics paper academic.oup.com/bioinformati...
#IDSky 🧪

Thrilled to announce our new paper in Bioinformatics. We present Topolow, a physics-inspired algorithm to create more accurate & stable antigenic maps, even from sparse data; also "antigenic velocity" showing the direction and magnitude of phenotypic changes.
🔗Paper: academic.oup.com/bioinformati...

#Tehran metro is 863 sq miles, all densly populated. It's twice the size of the entire Rocky Mt park.
All 5 boroughs of NYC are 303 sq mi.