Owen Dunkley
@odunkley.bsky.social
Molecular biologist currently pursuing a PhD in Bioengineering at Stanford, Greenleaf Lab.
Formerly @ McGill & Princeton. 🇨🇦 & 🇬🇧
Veeeery new to Bsky
Formerly @ McGill & Princeton. 🇨🇦 & 🇬🇧
Veeeery new to Bsky
Reposted by Owen Dunkley
I am so excited to share our project with you! We find prokaryotic proteases activate toxic enzymes and pores as a modular strategy in phage defense. We studied four fascinating protease-toxin pairs that are abundant across bacterial genomes:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Proteolytic activation of diverse antiviral defense modules in prokaryotes
Linked protease–effector modules are widespread in prokaryotic antiviral defense, yet the mechanisms of most remain poorly understood. Here we show that four of the most prevalent modules—metallo-β-la...
www.biorxiv.org
November 15, 2025 at 11:49 PM
I am so excited to share our project with you! We find prokaryotic proteases activate toxic enzymes and pores as a modular strategy in phage defense. We studied four fascinating protease-toxin pairs that are abundant across bacterial genomes:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...