@nvargesson.bsky.social
Developmental biologist studying how our limbs form and how and why they are the same length. And how Thalidomide caused limb differences and how its actions on the blood vessels result in the range of limb differences induced by Thalidomide. Views my own.
ZPA experiment…. Carried out In chick limb buds where graft the ZPA from a donor limb into the anterior of a host limb bud which induces a mirror image handplate! 6-8 digits instead of 3-4. Amazing! 50th anniversary of this amazing discovery/observation is in 2026…..
August 2, 2025 at 11:03 PM
ZPA experiment…. Carried out In chick limb buds where graft the ZPA from a donor limb into the anterior of a host limb bud which induces a mirror image handplate! 6-8 digits instead of 3-4. Amazing! 50th anniversary of this amazing discovery/observation is in 2026…..
Thank you @kevinthiessen.bsky.social i will miss ZR! You have been brilliant for the community. Thank you.
June 26, 2025 at 9:44 PM
Thank you @kevinthiessen.bsky.social i will miss ZR! You have been brilliant for the community. Thank you.
However Thalidomide alters yolk sac vasculature despite the absence of detectable Cereblon complex gene expression. Suggesting thalidomides antiangiogenic action may be independent of Cereblon.
March 29, 2025 at 12:36 AM
However Thalidomide alters yolk sac vasculature despite the absence of detectable Cereblon complex gene expression. Suggesting thalidomides antiangiogenic action may be independent of Cereblon.